Monday, January 09, 2023


Health Care Workers Cry Foul on FDA Claiming It Didn’t Prohibit Ivermectin for COVID-19

Dr. Yusuf Saleeby has practiced medicine for more than 30 years. He serves patients in South Carolina and until recently had never faced an investigation from his state medical board.

But after Saleeby started prescribing ivermectin to his patients, he was reported to the board, which opened an investigation, despite the state’s attorney general’s promise that his office wouldn’t prosecute doctors who prescribed off-label medications.

Jennifer Wright, a nurse practitioner and clinical director who practices in Florida, but can prescribe across state lines, told The Epoch Times she received a letter from the Office of the Attorney General of New York ordering her not to prescribe ivermectin.

“You know, basically threatened me. If I don’t stop prescribing, then they’re going to fine me,” Wright said about the letter, which threatened legal action with fines of up to $5,000 per violation.

The letter stated that the Food and Drug Administration only authorized ivermectin for use in humans when treating “parasitic worms and head lice and skin conditions like rosacea.”

The citation in the letter appears to be from an FDA advisory issued in March 2021 titled “Why You Should Not Use Ivermectin to Treat or Prevent COVID-19.”

That advisory and other anti-ivermectin messaging from the FDA are now the subject of a lawsuit brought by three doctors against the agency. The doctors argue that the FDA illegally interfered with their ability to treat patients. The suit was dismissed but an appeal has been filed by the plaintiffs.

During a hearing in 2022, attorneys defending the government argued that the agency’s missives were just a recommendation.

“They did not say it’s prohibited or it’s unlawful. They also did not say that doctors may not prescribe ivermectin,” Isaac Belfer, one of the lawyers for the government, said during a Nov. 1, 2022, hearing in federal court in Texas.

The government’s arguments differ greatly from the reality many doctors faced for prescribing ivermectin. Some lost their jobs, others were investigated by state medical boards, and many received threats from the New York attorney general because they were prescribing across state lines.

Matthew Dark, a spokesperson for Roots Medical and Colorado Healthcare Providers for Freedom, which has more than 275 physicians in the group, stated that several doctors in Colorado are facing investigations by the state medical board.

When asked about the FDA’s new claim, Dark stated: “They knew it was safe for humans, and they made that very accusatory thing if you were a doctor prescribing this, you were an idiot. You were practicing like a hillbilly. So that message was loud and clear.”

Dark referred to Twitter posts from the FDA, one of which said: “You are not a horse. You are not a cow. Seriously, y’all. Stop it.”

“Pharmacies were responding to the practice and providers trying to write [ivermectin] the same way the FDA was behaving,” Dark said.

Wright concurred, and pointing to her letter from the New York attorney general, said, “It clearly states in this letter that according to the FDA, you must cease and desist in prescribing ivermectin to New York State residents.”

Dr. Miguel Antonatos, a board-certified internal medicine physician who practices out of Illinois, but can prescribe to other states, told The Epoch Times via email that he, too, received a letter from the New York attorney general.

Nicole Sirotek is a registered nurse and founder of American Frontline Nurses, a patient advocacy network that boasts 22,000 nurses. She told The Epoch Times that her nurses often work with doctors in hospital settings.

At the height of the pandemic, Sirotek said patients would reach out to her advocacy network and beg for ivermectin, either for themselves or their loved ones dying in the hospital.

She stated that in five separate instances, doctors were fired or forced to resign for prescribing ivermectin as a home medication for nurses to administer in hospitals.

“That happened five times, and each physician was fired. That’s five physicians in five different states and five different hospital systems.”

Julie McCabe, a registered nurse and director of advocacy services for American Frontline Nurses, told The Epoch Times that the above doctors include Dr. Edith Behr in Pennsylvania, Dr. John Witcher in Mississippi, Dr. Mary Bowden in Texas, Dr. Robert Karas in Arkansas, and Dr. Paul Marik in Virginia. Bowden and Marik are two of the three doctors suing the FDA over its stance on ivermectin.

Bowden told The Epoch Times that Houston Methodist Hospital suspended her for merely writing on Twitter about ivermectin, and she had to overcome “numerous obstacles” when prescribing it to patients.

“The FDA was the key creator of these hurdles when it launched a social media campaign stating that ivermectin is dangerous and only for horses. When faced with a lawsuit, the FDA now claims it was merely making suggestions—suggestions that have threatened my ability to practice medicine and more importantly, interfered with life-saving early treatment of COVID patients,” Bowden said.

Sirotek said members of the group Team Halo targeted her because of her stance on ivermectin. The group describes itself as “volunteer scientists and healthcare professionals from around the world, working to end this pandemic by contributing our time to address concerns and public health misinformation.”

Members of the group filed several complaints to Nevada’s state medical board, which Sirotek said costs her $5,000 per complaint to fight.

With tears streaming from her eyes, Sirotek said she’d also received death threats, pictures of her house, and threats to murder her children. Sirotek provided copies of these threats to The Epoch Times. Team Halo didn’t respond to a request by The Epoch Times for comment.

In the spring of 2020, with COVID-19 spreading like wildfire through the population, finding a viable treatment was paramount in many doctors’ minds. And as no drug was approved to treat the novel virus, they turned to off-label use, a standard medical practice even in non-pandemic times.

In March 2020, a group of leading critical care specialists joined forces and formed the Front Line COVID-19 Critical Care Alliance (FLCCC). Their mission was to examine different therapies and drugs and recommend possible COVID-19 treatments based on best medical practices and emerging data.

Almost immediately, ivermectin was put forward as a possible treatment. First approved for human use in 1987 and dispensed billions of times since then, ivermectin is traditionally prescribed to treat parasites. But it’s safe and was already known to have an effect on viruses.

“This is a medication that is safer than Tylenol, safer than stuff we sell over the counter,” Wright said.

Saleeby agreed.

“[Ivermectin is] probably one of the most prescribed drugs. It’s given out like candy in Sub-Saharan Africa and Amazon basin or anywhere around water. … It’s doled out to children and pregnant women. … As far as safety, it’s probably safer than baby aspirin. It’s probably the safest drug on the planet, to be honest.

“I was using [ivermectin] sporadically in some of my Lyme patients. It’s effective against Lyme. We knew it had effectivity against viruses and other pathogens like Borrelia and Babesia.”

Sirotek told The Epoch Times that, especially as the Delta strain increased hospitalizations and deaths in the United States, she and several nurses questioned why some countries seemingly remained unaffected. The answer, she believes, was widespread ivermectin use.

At first, prescribing ivermectin and obtaining it from a regular pharmacy wasn’t an issue, Wright said. More importantly, it worked.

“We started using it very early on, and I could prescribe it to the pharmacy. I would prescribe it according to the FLCCC recommendations because they were the ones doing the research. I was just validating that, you know, this has some real stuff behind it.”

When the pandemic began, ivermectin as an effective treatment was primarily a theory. But as health care workers reported that it worked, more and more studies were conducted to back up those early successes.

There have been 189 ivermectin COVID-19 studies, according to the aggregate site C19ivm.org. Of those studies, 139 have been peer-reviewed, and 93 compare treatment and control groups.

In the 93 studies, which had more than 133,838 patients in 27 countries, there were “statistically significant improvements are seen for mortality, ventilation, ICU admission, hospitalization, recovery, cases, and viral clearance,” a real-time meta-analysis states.

Simply put, as health care workers saw firsthand that ivermectin worked in their practices, studies were simultaneously confirming the medicine’s effectiveness.

Dr. Peter Raisanen, a naturopathic medical doctor in Arizona, said that once he started his patients on ivermectin, they typically started feeling better within a few days.

“It seemed like it was within three to four days, like they [started feeling] better,” Raisanen told The Epoch Times.

Raisanen said he treated about 200 patients with ivermectin, and none died. Almost all stayed out of the hospital. That’s an experience several doctors attested to witnessing.

“We’ve probably collectively [at Roots Medical], treated 1,000 people with early COVID,” Dark said.

He said that when a patient was treated early on in their illness, there was a clear improvement—often within hours.

“It’s within two hours of that first dose that people start feeling noticeably better. And within two days, most symptoms are gone. Again, this is with starting early treatment, say days one to three, one to four, of infection or symptoms,” Dark said.

Sirotek said the nurses in her network partnered with My Free Doctor’s Dr. Ben Marble and his network of physicians. Altogether, the group treated more than 300,000 patients with early ivermectin intervention. She said of those 300,000, only three died.

Saleeby didn’t specify the exact number of patients treated.

“I’ve seen some miraculous things in the patients that I prescribed ivermectin to, who follow our instructions, and get on it right away at the appropriate dose and do the nutraceutical bundles,” he noted. “[They] are not going into the hospital and they’re not dying.”

Saleeby said that he treated himself with ivermectin when he caught COVID-19. He credits its use with keeping him out of the hospital.

Pharmacies Impede Treatment

While ivermectin was obtainable from traditional pharmacies at the start of the pandemic, health care providers soon started to get pushback. “As I started prescribing [ivermectin] to more and more people, I started getting calls from pharmacists,” Wright said.

Susan Julian, a nurse practitioner and certified functional medicine practitioner with a practice in Indiana, said the first time she realized something was amiss was when one of her patients contacted her after she prescribed him ivermectin.

Julian said that when her patient tried to have his prescription filled, the pharmacists asked him if it was for parasites. When the patient said it was for COVID-19, the pharmacists “hassled him right there in the store,” she told The Epoch Times. “Pharmacists are not supposed to ask people, ‘Why are you taking this medication?’ It’s not their business unless you make it their business,” Julian said.

Shortly after, the pharmacies started calling Julian and stating they wouldn’t fill her prescriptions for patients.

Dark, whose Colorado Healthcare Providers for Freedom network includes 275 doctors in Colorado, added that the pushback from pharmacies on ivermectin fulfillment was without precedent.

“There has never been a drug, like ivermectin, so singular at being picked out and said that ‘we will not fill under any circumstances.’ That has never happened before,” Dark said.

The refusals to fulfill prescriptions soon turned to threats.

“I had pharmacists tell me that they’re recording me for misinformation. For doing harm to my patients,” Wright said.

Circling back to the FDA and opposing ivermectin, Saleeby said: “[The FDA] really did go way out of the way to make it difficult for doctors to feel comfortable using it. By threatening their licenses, by kind of bullying them, if you will, into not prescribing it. To just go along with the narrative.”

Answering the ‘Why’

The FDA’s website states that if a viable treatment exists for an illness during a health emergency, neither medications nor vaccines may be approved using an emergency use authorization.

While there isn’t concrete proof for their position, some doctors and nurses interviewed by The Epoch Times theorized that the FDA’s pushback against ivermectin was motivated by the need to secure an emergency use authorization for the COVID-19 vaccines.

“They had an agenda. And the agenda was to push this new form of vaccine, this mRNA vaccine, because it was going to make the industry billions of dollars. And in order for them to promote this because they didn’t have the time to do randomized control trials for efficacy and safety, they had to use Emergency Use Authorization [EAU],” Saleeby said.

“It completely destroys the vaccine position,” Dark concurred. “One thing that’s written very clearly is that you cannot have a known acceptable form of treatment out there available to the public and still be operating under emergency use.”

“If there was a possible treatment for COVID-19, the vaccine would not be able to obtain emergency authorization use,” Wright said. “If there’s any possible treatment, then the vaccines would have to go through rigorous testing.”

The Epoch Times sought comment from the FDA, Dr. Anthony Fauci, the state medical boards in Colorado and South Carolina, CVS, Walgreens, King Soopers, and the New York Attorney General’s office.

The Colorado Department of Regulatory Agencies stated, “Any complaint that may have been received by the Colorado Medical Board as part of an investigation is confidential and unavailable for public inspection pursuant.”

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Sunday, January 08, 2023



More Than 270 Deaths in US Athletes After Vaccination

Over 270 athletes and former athletes in the United States have died from cardiac arrests or other serious issues after taking COVID-19 vaccines, according to data from a recent peer-reviewed letter to the editor.

Authored by structural biologist Panagis Polykretis, and board-certified internist and cardiologist Dr. Peter McCullough, the letter’s cited data found that from 2021 to 2022, at least 1,616 cardiac arrests or other major medical issues have been globally documented in vaccinated athletes, with 1,114 of those being fatal.

The global data also showed that between 2021 to 2022, former and current American athletes made up 279 of the mortalities.

Athletes have a lower chance of cardiac arrest and sudden cardiac death as compared to nonathletes. A 2016 U.S. study calculated that nonathletes, compared to athletes, have a 29 times higher chance of sudden cardiac death.

One of the reasons is because “athletes are screened out for the common causes of sudden death on the playing field,” McCullough told The Epoch Times.

Players are screened for hypertrophic cardiomyopathy, which makes up almost 50 percent of sudden cardiac deaths in athletes, as well as other less common heart abnormalities.

The intensive screening is what makes competitive-level sports safer than everyday sporting activities, McCullough argued.

Sudden Cardiac Deaths in Athletes Increased After Vaccination

McCullough pointed to a European study that tracked sudden cardiac deaths in European athletes over 38 years from 1966 to 2004. The study reported 1,101 sudden cardiac deaths over the interval, which Polykretis estimated would be around 29 deaths per year.

In the United States, it is estimated that 100 to 150 athletes die every year from sudden death.

The data cited in the letter, however, showed that in 2022 alone, over 190 deaths from cardiac arrests or other factors have been reported in current and former athletes.

This does not include the deaths of athletes with unknown vaccine statuses and those whose names did not make it into the media.

McCullough said looking at the data, “there’s no doubt,” that sudden cardiac deaths have increased following vaccinations.

However, since most of the sudden cardiac deaths in the media are of professional competitive players, McCullough added that collecting data from athletes in colleges, high schools, and other international leagues would give a more comprehensive picture.

He pointed to studies that have shown high myocarditis increases following COVID-19 vaccinations.

Prior to the pandemic, a 2017 study in Finland found that myocarditis rates were 19.5 per million for children 15 years of age and younger. Another 2012 Japanese study on pediatric admissions reported even lower rates of 2.6 cases per million in children aged 1 month to 17.

In the data released by the Centers for Disease Control (CDC) and Prevention in June 2021 (pdf), researchers expected myocarditis rates in vaccinated 12- to 17-year-old males to be 63 cases per million. By the following year, researchers at the CDC noted that myocarditis numbers in young males were exceeding the background rates (pdf).

A study by researchers from Kaiser Permanente (pdf), published in August 2022, estimated myocarditis would be 186 cases out of a million, after a second dose of vaccine in 12- to 17-year-old children. In males, this number was raised to 377 cases out of a million.

However, in prospective studies, one Thai study found that 2.3 percent of children who received two shots of mRNA doses had a heart injury. Another study evaluated 777 health care workers who were boosted and 2.8 percent reported a heart injury.

This means that if the results are extrapolated, around 25,000 people per million could suffer from heart injuries after two or three doses of COVID-19 vaccinations, according to McCullough.

“I’m very concerned,” said McCullough, “This is a public health problem. I think it is incumbent upon individuals to disclose the vaccine status.”

“We see the report of public figures or athletes one after another, dying suddenly, with no explanation. It’s incumbent upon the families, the medical staff, the doctors, and the reporters to disclose the vaccine status. They are investigational vaccines, and they are linked to death in peer-reviewed studies.”

A German autopsy study evaluated 25 people who died unexpectedly within 20 days of being vaccinated. Four of the individuals were found with myocarditis without any other disease signal that may have caused the unexpected death.

The authors concluded that their autopsy studies indicated that deaths were due to cardiac failure, and that myocarditis could be “a potentially lethal complication following mRNA-based anti-SARS-CoV-2 vaccination.”

It should also be noted that myocarditis events have also been reported in unvaccinated COVID-19 patients in 2020, and studies have shown that the virus can cause heart damage. But it is debatable if the heart injuries patients experience are caused by myocarditis or some other reasons.

A study published in April 2022 found that increases in myocarditis and pericarditis are statistically insignificant among unvaccinated individuals after COVID infection. The researchers evaluated around 197,000 unvaccinated patients, and there were 9 and 11 cases of myocarditis and pericarditis, respectively.

A French study that tracked cardiac arrests in athletes pre-pandemic from 2005 to 2018 also found that the rate of cardiac arrests in sports has remained constant, while survivability of these events has increased due to help from bystanders.

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Twitter Suppressed Early COVID-19 Treatment Information and Vaccine Safety Concerns: Cardiologist

Thanks to Elon Musk, the public is now aware that Twitter suppressed early treatment options for COVID-19, and vaccine safety concerns, Dr. Peter McCullough alleged in an interview that aired on Newsmakers by NTD and The Epoch Times on Dec. 14.

Further, thanks to the Twitter Files—a collection of internal emails and communications made public by Musk—the cardiologist said there’s proof that government agencies were working against him (McCullough) personally.

“I didn’t violate any of Twitter’s rules,” McCullough stated. “And what we’re learning is that secret emails between government agencies and Twitter were working to, in a sense, shadow-ban me, censor me, and inhibit my ability to exercise my rights to free speech and disseminate scientific information.”

McCullough said Musk’s takeover of Twitter is a “welcome change,” especially for healthcare professionals like himself.

“Twitter had become an incredibly biased and censored platform, where the public knew they weren’t getting a fair, balanced set of information on a whole variety of developments—including the early treatment of SARS-COV2 infection and a balanced view of safety and efficacy of the vaccines,” McCullough claimed.

The cardiologist further claimed that he was censored and finally suspended for sharing scientific “abstracts and manuscripts,” which didn’t fit the accepted political view. Plus, McCullough remarked, he wasn’t the only doctor targeted.

Musk lifted the suspensions of McCullough and mRNA vaccine technology contributor Dr. Robert Malone—suspended from Twitter in 2021 after criticizing the effectiveness of the mRNA vaccines—after completing his Twitter purchase.

Social Media and Censorship

According to McCullough, when a social media company has a COVID-19 warning or labels a post “misinformation,” that’s a sign of government censorship and control.

“Facebook, Instagram, and the other platforms. … Anytime a message is posted, and it says, ‘See the COVID information center,’ or it labels it ‘COVID misinformation,’ that actually indicates that there’s government interference. There’s government censorship going on,” McCullough asserted.

He added that when a user witnesses the above, they need to call out that platform. Moreover, McCullough believes there needs to be a “complete overhaul” of social media leadership and a “cleansing” of all forms of censorship on social media sites.

He said explicitly regarding healthcare that a past U.S. Supreme Court ruling guaranteed physicians free speech and medical authority, and social media platforms are violating that ruling.

“Physicians, including myself, our rights to free speech were guaranteed in a Supreme Court ruling. We have medical authority, and the public is looking to our analyses and our guidance through the rest of this pandemic.”

Drug and Vaccine Lies

Regarding the safety of vaccines and the pushback he received when he voiced his concerns, McCullough stated, “There is no drug or vaccine that is free of side effects. There’s no drug or vaccine that’s perfectly effective.

“So, when Americans were seeing advertisements that said ‘safe and effective,’ of course, immediately, we were jumping and making the case based on the peer-reviewed literature that that’s not correct.”

McCullough further noted that he and author John Leake have released a book called “The Courage to Face COVID-19″—detailing the true story of the “intentional suppression of early treatment [of COVID-19] by what we call the biopharmaceutical complex.”

McCullough explained that what he meant by “biopharmaceutical complex” is the amalgamation of Big Pharma, government interests, and foundations, including everything up to the World Economic Forum.

He further alleged that this complex had one mission—mass vaccination—so they purposefully buried early treatment “to favor the vaccine strategy.” McCullough acknowledged that his allegation was “complex and mind-blowing” but said Americans know it’s reality and not a conspiracy.

McCullough also stated that creating a Public Health Integrity Committee by Florida’s Republican governor Ron DeSantis (ostensibly to make sure politics don’t suppress public health information in the future) is a validation of doctors like himself.

The Twitter Files

Since taking over Twitter, Musk has become increasingly vocal about transparency and the need for people to see what happened behind the scenes at the tech company. To that end, he released secret emails and discussions about shadow-banning or removing accounts that didn’t toe the party line.

As part of its reporting, The Epoch Times sought comment from the DOJ and FBI on the Twitter Files revelations and their involvement with social media companies.

The FBI National Press Office replied, “The FBI regularly engages with private sector entities to provide information specific to identified foreign malign influence actors’ subversive, undeclared, covert, or criminal activities.

It is not based on the content of any particular message or narrative. Private sector entities independently make decisions about what, if any, action they take on their platforms and for their customers after the FBI has notified them.”

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Friday, January 06, 2023



Breathing Trouble

New research shows the risks from prolonged use of face masks

There’s an old story about a guy who jumped into a thorn bush: He wanted to collect berries, but he failed to consider the adverse effects of the plan. Something similar happened with face masks during the COVID-19 pandemic: Masks were promoted, and often mandated, as necessary safeguards for reducing the chance of infection, while their possible adverse effects were brushed aside. While the science on the benefits of masking is still inconclusive, the latest research now shows that the prolonged use of face masks—especially those with tighter fits like the N95s—could harm wearers by exposing them to dangerously high levels of carbon dioxide.

The risks appear to be especially pronounced for young people. As part of a team of scientists, one of the authors of this article conducted a randomized study of the effects of masking on healthy school aged children in Germany. The results of this research, published in September 2022 in the peer reviewed journal Environmental Research, concluded that wearing masks raised the carbon dioxide (CO₂) “content in inhaled air quickly to a very high level in healthy children in a seated resting position that might be hazardous to children’s health.”

These results should not have come as a surprise. It has long been suspected that mask-wearing poses risks. In Germany, for instance, workers required to wear an N95/FFP2 respirator must get a certificate verifying their ability to do so, and even with said certificate, those workers are mandated to take a 30-minute break every 90 minutes.

Only in the 19th century, with the development of germ theory, did masks begin being used as health devices. Then in the early 20th century, masks gained a foothold in hospitals, usually worn by doctors and nurses. The “Spanish flu” pandemic of 1918-20 was perhaps the first case of masks being worn by the general public, but we only have scattered photographic pictures of masked people and don’t know how frequently they were worn.

During the 20th century, most scientists believed that masks could be useful only in hospitals for the prevention of surgical wound infections in high-risk cases. Still in 2010, a study overseen by Dr. Ben Cowling, a professor of public health at the University of Hong Kong, found weak evidence, if any, that masks could be a useful tool for stopping airborne infections.

There’s thus every reason to believe that, in March 2020, when Dr. Anthony Fauci discouraged Americans from wearing masks, he was simply stating a widely accepted medical orthodoxy. Population-level mandatory face masking had never been attempted before, and there was no reliable data proving its effectiveness, nor data detailing its adverse effects. It was reasonable to be cautious before recommending such a drastic and untested solution.

Yet this attitude rapidly changed, most likely because of political factors. It is not that politicians were directly meddling with medicine; more likely, they simply wanted to be seen as “doing something.” Masks offered visible evidence that the leaders were acting against the pandemic, and so masks appeared to be a good idea. The medical authorities rapidly sensed what was expected of them—back up the politicos—and they complied, even in the absence of data supporting the decision.

After more than two years of widespread masking, which remained mandatory for young school children long after it was abandoned by the politicians who imposed such measures, we are starting to see more data. But many studies are of poor quality, performed on small populations, based on questionable assumptions, using debatable statistical methods, and often using air that is unnaturally saturated with viral particles.

Some studies do indicate that, at least in some conditions, masks can slow down the diffusion of the SARS-CoV-2 virus. Masks are not, however, a miracle device that can fully stop the virus. As doctors were saying in early 2020 before the public health establishment reversed its position on the issue, aerosol particles carrying the coronavirus are simply too small to be completely stopped by the filtering tissue of standard masks, and even less so because of how often masks are worn incorrectly.

It is our view, then, after considering the available scholarship, that we cannot establish any clear and conclusive benefits to widespread masking.

Can we establish the presence of any harmful effects? Here, we enter a complicated field of study, as it is difficult to determine the adverse effect of masks on wearers. Such a gap in knowledge is part of a pattern: In the history of medicine, there have been some glaring failures in detecting adverse effects. You may remember, for instance, the story of thalidomide, a drug marketed in the 1950s as a sedative, that was later found to cause birth defects. It had not been properly tested on pregnant women.

One problem with determining adverse effects is that you can’t knowingly expose people to something that you suspect causes serious harm, not even in the name of science. The Nuremberg Code, a set of international ethical principles created after the Doctors Trial for Nazi medical war crimes, prohibits experimentation on human subjects without their explicit consent. Another problem is that adverse effects are often delayed in time. Think of the health effects of cigarettes. Nobody ever died because they smoked one cigarette. After several decades of studies, however, it was possible to determine that if you are a smoker your life expectancy is reduced by a significant number of years.

Just like smoking a single cigarette never killed anyone, wearing a face mask for a few hours or a few days does not cause irreversible damage either. But the immediate short-term physiological effects are detectable: A recent study led by Pritam Sukul, senior medical scientist at the University Medicine Rostock in Germany, found masks to cause hypercarbia (high concentration of CO₂ in the blood), arterial oxygen decline, blood pressure fluctuations, and concomitant physiological and metabolic effects.

On a time scale of weeks or months, these effects appear to be reversible. But how can we know what can happen to people who wear masks for several hours a day for several years? Will we have to wait for decades before concluding that masks are bad for people’s health, as was the case with cigarettes?
Not necessarily, for we are able to assess face masks in terms of the air quality breathed by the wearers. One important parameter for air quality is CO₂ concentration. Over the years, a lot of data has been accumulated in this field from miners, astronauts, submariners, and other people exposed to high concentrations of CO₂.

Measurable negative effects on mental alertness already occur at CO₂ concentrations over 600 parts per million (ppm), which is only slightly higher than the average concentration in open air (a little more than 400 ppm). Values higher than 1,000-2,000 ppm are not recommended for living spaces, especially for children and pregnant women. 5,000 ppm is the commonly accepted limit in working environments or in submarines and spaceships. Concentrations in the range of 10,000-20,000 ppm are not immediately life-threatening but can only be withstood for short periods. Even higher concentrations may lead to loss of consciousness and death.

So what kind of CO₂ concentration are people exposed to when they wear a face mask? Measuring the concentration of CO₂ inside the small volume of a face mask while it is being used poses practical problems, and there are no standardised methods and procedures to evaluate this. Nevertheless, during the past few years, several papers dealing with this subject were published.

Some of these papers were criticised, but often baselessly. For instance, some fact checkers claimed that the same amount of CO₂ could be found without face masks in exhaled breath. This is true, but trivial. The studies mentioned above measured the amount of CO₂ in the inhaled air under face masks; the fact checkers measured the air exhaled. Other fact checkers provided a priori statements by “experts,” including a sports reporter.

Meanwhile, studies that rely on robust capnographic methods that calculate inhaled CO₂ levels from the end-tidal volume of CO₂ under strictly controlled conditions have corroborated our findings about elevated CO₂ levels in masks. In short, there is strong evidence that people wearing face masks, especially the FFP2/N95 type, breathe a concentration of carbon dioxide several times higher than the recommended concentration limits, in the range of over 5,000 ppm and often over 10,000 ppm. In other words, masks may multiply the external CO₂ concentration by a factor of 10, if not more.

Individuals wearing a tight, N95-style face mask are thus breathing air of comparable quality to the air in spacecrafts and submarines. Astronauts and submariners, though, are well trained and in peak physical condition; masks, meanwhile, are often worn by the elderly, the young, and people affected by chronic pathologies. A recent study of more than 20,000 German children who wore masks for an average of more than four hours per day showed that 68% of them reported these kinds of problems.

There are additional risks associated with face masks that should be considered, such as psychological effects and infections from pathogens accumulated in the mask tissue, but we believe that the increased concentrations of CO₂ breathed by mask-wearers is a clear and demonstrated adverse effect that should be known and considered when deciding policies. In short, face masks are not harmless.

Wearing a face mask is not a purely symbolic gesture like wearing a lapel pin or waving a flag, as some people have come to believe. It is not simply an expression of social solidarity, belief in science, or support for health care workers. It can have important adverse effects on health—especially in the case of N95s—and, at the very minimum, citizens should be alerted to the downsides of masking before they make up their minds on the issue. Face masks should be mandated only in special circumstances, and ordinary citizens should wear them only when there is a real and evident risk of infection.

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Australian woman opens up about her devastating vaccine injury

The wife of high-profile doctor Kerryn Phelps has detailed the horrific side effects in her first interview about her battle with a debilitating Covid vaccine injury.

Jackie Stricker-Phelps told Daily Mail Australia her life as she once knew it is gone and there is no prospect of recovery from her vaccine injury.

The former schoolteacher's symptoms started minutes after her first Pfizer jab in May 2021 and she is still unable to walk without pain.

She is one of thousands of Australians who suffer devastating long-term side effects, but feel like the government and medical regulators deny it's happening.

'I have had debilitating neurological and rheumatological effects since the initial Pfizer vaccine,' she said.

'I had a surge of heat in my head, my face went bright red, my gums and sinuses started to throb, I felt my hands and feet go numb and I developed pins and needles all over my torso, arms and legs. 'I could hardly walk, and so begin the next 19 months of hell.'

Ms Stricker-Phelps said she saw a neurologist the next day, who closely monitored her symptoms, and later also visited a rheumatologist.

'I have had visual disturbance, nerve pains, burning gums, flushed face, hair loss, musculoskeletal inflammation, and night sweats,' she said. 'I tried multiple prescribed medications, steroid injections into my spine and hips for pain.

'Two of my specialists have confirmed it is a vaccine injury and say they see other people with the same adverse events.'

Both she and Dr Phelps, who also suffered a serious vaccine injury from her second Pfizer jab, investigated the possible risks before getting vaccinated.

'We were told the most common symptoms were a sore arm with maybe a temperature for a few days and a rare possibility of anaphylaxis. We were both told it was far safer to get the vaccine than the illness,' she said.

To manage the risk of anaphylaxis, Ms Stricker-Phelps had her shot in a hospital and was observed afterwards by Dr Phelps, another doctor, and a registered nurse.

When her symptoms began, she claimed the nurse told her 'this is not anaphylaxis so you can go home' despite her barely being able to walk.

Ms Stricker-Phelps said her symptoms had not shown any significant improvement and frequent flare-ups made her unable to perform many basic tasks.

In the midst of a recent flare-up, she found it extremely painful to walk, communicating was difficult, and she struggled to leave the house.

'Flareups are even harder to deal with as there are no protocols in place for treatment,' she said.

To deal with the latest one, her specialist sent her for 'yet another spinal injection' to try to reduce inflammation across her body.

Even when the flare-ups subside, exercise is difficult because of the pain she suffers throughout her body.

But she said the hardest thing was having to live an isolated life to avoid catching Covid.

'I cannot receive any more of the current vaccines so am not protected from Covid,' she said. 'I have to isolate from family and friends, and avoid group activities such as parties or the theatre as the virus is transmissible even from vaccinated people.'

Ms Stricker-Phelps said she had no idea if and when her condition would improve, let alone recover, because so little was known about it. 'The best chance of recovery is for more effort and funding into research to find the underlying mechanism of the injury and for specific treatments to be developed,' she said.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

**************************************************

Thursday, January 05, 2023



‘Twitter Files’ Reveal How the Left Uses Big Tech to Create an Illusion of Scientific Consensus and Stifle Debate, Especially on COVID-19

The Left has long used the notion of scientific consensus as a tool to silence debate on controversial issues, but the Twitter Files revealed just how far some Big Tech companies have gone to suppress legitimate scientific dissent—particularly on COVID-19 pandemic policy.

Dr. Jay Bhattacharya, a Stanford professor of health policy who wound up on a Twitter Trends blacklist after he argued for focused protection of the vulnerable and an end to lockdowns, opened up in an article for The Free Press about the lesson he learned in 2022.

“I learned in a very concrete and painful way the effects of Washington and Silicon Valley working together to marginalize unpopular ideas and people to create an illusion of consensus,” Bhattacharya wrote.

The Stanford professor recalled that after he and his allies published the anti-lockdown Great Barrington Declaration, National Institutes of Health Director Francis Collins dismissed him and his allies as “fringe epidemiologists” and asked Anthony Fauci for “a quick and devastating published takedown” of the declaration. Collins and Fauci collaborated to delegitimize the declaration, even though it was based in scientific principles and even though it predicted much of the now-acknowledged fallout from the lockdowns.

Twitter’s COVID-19 censorship spread far beyond Bhattacharya, as the Free Press journalist David Zweig revealed in an installment of The Twitter Files.

Twitter cast aspersions on the medical opinion of Dr. Martin Kulldorff, an epidemiologist at Harvard Medical School, because he disagreed with Centers for Disease Control and Prevention guidelines on the COVID-19 vaccine.

“Thinking that everyone must be vaccinated is as scientifically flawed as thinking that nobody should,” Kulldorff wrote. “COVID vaccines are important for older high-risk people, and their care-takers. Those with prior natural infection do not need it. Nor children.”

Even though Kulldorff’s statement represented both an expert opinion and the rationale behind vaccine policies in other countries, Twitter deemed it “false information” because it differed from CDC guidelines.

In a particularly egregious example, Twitter took action against a tweet that corrected actual misinformation, using the CDC’s own data.

A user wrote that “since December of 2021 COVID has been the leading cause of death from disease in children.” Kelley Kga, a self-proclaimed public health fact-checker, responded with data from the CDC demonstrating that COVID-19 was not the largest disease-related cause of death among children.

Twitter flagged the tweet as “Misleading,” disabling replies and likes. The platform added a note about health officials supporting the COVID-19 vaccines, an issue the tweet in question did not address.

Rhode Island physician Dr. Andrew Bostom found himself permanently suspended from Twitter after receiving five strikes for misinformation. After Bostom’s attorney contacted Twitter, the company’s internal audit found that only 1 of his 5 violations had been valid.

Yet even that tweet contained legitimate data: Bostom had cited data showing that the flu is more lethal than COVID-19 for children, and that COVID-19 vaccination causes more serious morbidity than flu vaccination for kids.

In another egregious example, Twitter executives seem to have been tempted to censor former President Donald Trump merely for expressing optimism about the pandemic. On Oct. 5, 2020, Trump tweeted that he was leaving Walter Reed Medical Center and said he was “feeling really good! Don’t be afraid of Covid. Don’t let it dominate your life.”

Jim Baker, then Twitter’s deputy general counsel, asked Yoel Roth, then Twitter’s head of Trust and Safety, “Why isn’t this POTUS tweet a violation of our COVID-19 policy (especially the ‘Don’t be afraid of Covid’ statement)?”

While Roth has a history of advocating censorship, he stood with common sense on this case. He noted that “this tweet is a broad, optimistic statement. It doesn’t incite people to do something harmful, nor does it recommend against taking precautions or following mask directives (or other guidelines). It doesn’t fall within the published scope of our policies.”

Zweig noted that “Twitter made a decision, via the political leanings of senior staff, and govt pressure, that the public health authorities’ approach to the pandemic—prioritizing mitigation over other concerns— was ‘The Science'” and targeted information that challenged that view for moderation or suppression.

Yet Big Tech has taken action to suppress dissent from liberal narratives on science on far more topics than just COVID-19.

As I reported for Fox Business in 2021, Facebook has promoted false claims about a climate change consensus by adding fact-check-style “information” notes to various posts.

Facebook launched the “Climate Science Information Center” in February 2021 in the United Kingdom an expanded the effort to more than 100 countries ahead of the COP26 summit in Glasgow, Scotland.

Facebook put a note reading, “See how the average temperature in your area is changing” to certain climate-related posts. The note directs users to a climate center, which states that “the cause of climate change is widely agreed upon in the scientific community.”

“At least 97% of published climate experts agree that global warming is real and caused by humans,” the Facebook center claims. “The myth that scientists disagree on climate change sometimes comes from misleading petitions that don’t accurately represent the climate science community.” Facebook warns that such petitions “typically include non-scientists and scientists working in unrelated fields.”

Other graphics on the Facebook climate center argue that “no natural factors can explain how fast the planet is warming today.”

The 97% claim is not just unreliable, it’s patently false. Facebook’s claim traces back to a study led by John Cook entitled “Quantifying the consensus on anthropogenic global warming in the scientific literature” and published in the journal Environmental Research Letters in 2013.

The study analyzed all published peer-reviewed academic research papers from 1991 to 2011 that used the terms “global warming” or “global climate change.” The study organized these papers into seven categories, combining three categories to come up with 3,896 papers, comparing those with other categories, which made up 118 papers. Yet the study completely discounted the vast majority of the papers it analyzed (66.4%, 7,930 of the 11,944 papers). Only by excluding these papers did the authors come up with a 97% figure.

Many of the scientists who wrote the original papers Cook’s team analyzed complained that this study mischaracterized their research. The survey “included 10 of my 122 eligible papers. 5/10 were rated incorrectly. 4/5 were rated as endorse rather than neutral,” complained Richard Tol, professor of the economics of climate change at Vrije Universiteit.

Big Tech platforms have also promoted pro-abortion messages and speakers over pro-life ones.

A month after the Supreme Court overturned Roe v. Wade, YouTube announced that it would “remove content that provides instructions for unsafe abortion methods or promotes false claims about abortion safety under our medical misinformation policies.”

While it makes sense to suppress videos encouraging dangerous self-managed abortions, this statement also applies to YouTube’s policy against content that contradicts “expert consensus” on “chemical and surgical abortion methods deemed safe by health authorities.”

Google has used this policy to ban Live Action’s ads promoting the abortion pill reversal, a practice that has saved at least 2,500 children, according to Live Action President Lila Rose.

Google has agreed to delete location history for those visiting abortion clinics, and in 2018, a Slate writer bragged that her email to Google encouraged the company to change its YouTube search algorithm for “abortion,” promoting groups like Planned Parenthood over videos exposing the gruesome reality of abortion.

Big Tech has also targeted dissent from transgender orthodoxy. In October 2018, the platform expanded its “hateful conduct” policy to include “targeted misgendering or deadnaming of transgender individuals.” Many news outlets, including Focus on the Family’s Daily Citizen, The Christian Post, and PJ Media, along with the Christian satire site The Babylon Bee, have found their Twitter accounts suspended for the crime of referring to Dr. Rachel Levine, a Biden administration official and biological male who identifies as female, as a man.

YouTube has also moved against The Daily Signal and The Heritage Foundation, censoring the testimonies of a doctor and a man who previously identified as a woman. (The Daily Signal is the Heritage Foundation’s news outlet.)

Levine, the assistant secretary of health at the federal Department of Health and Human Services, has urged medical professionals to advocate for transgender identity and even urged them to pressure Big Tech to “create a healthier, cleaner information environment.” He said this right after lamenting the spread of “misinformation” on “gender-affirming care” and falsely claiming that “the positive value of gender-affirming care for youth and adults is not in scientific or medical dispute.”

While COVID-19 provides the most recent and arguably most egregious example, each of these cases shows how the Left and Big Tech use the illusion of scientific consensus to stifle public policy debates. On the pandemic, climate change, abortion, and transgenderism, the science is not settled in favor of the Left’s policy agenda, and Big Tech themselves are spreading misinformation when they claim that it is.

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Immunity from previous infection protects from new Covid strain

Only one in five people who reported an infection in December were known to have had COVID-19 previously, according to the ACT government.

While data is unavailable for most of the country, the numbers from the ACT suggest that past exposure to the disease provides some protection against the prevailing strains.

This contrasts with widely publicised fears that newer COVID-19 subvariants are highly effective at evading the body's immune defences.

The ACT is one of few jurisdictions that reports its reinfection rate, though its outbreaks largely mirrored those in New South Wales and Victoria last year.

About 46 per cent of Australians had already had COVID-19 by June last year, according to an analysis of antibodies in blood samples.

That proportion is almost certainly far higher today. This, combined with the ACT data, suggests a previous infection is strongly associated with avoiding infection during this latest surge.

Infectious diseases specialist Sanjaya Senanayake, an associate professor at the Australian National University, said the ACT data reflected what was happening overseas.

Singapore, for example, was also reporting that about 20 per cent of known new cases were reinfections.

Dr Senanayake said this relatively small number of reinfections showed that immunity — whether from vaccines or past exposure — was working for most people.

"It's hard to differentiate, in a place like Australia, between purely vaccine-induced immunity and infection-induced immunity, because many of us have both been COVID-19-infected and have had [several] vaccines," he said.

"This is hybrid immunity we're seeing.

"And what it tells us is that, even though in laboratory settings … these new subvariants have the potential to evade the immune system, this hybrid immunity is providing good protection."

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

**************************************************

Wednesday, January 04, 2023


Long COVID: 4 Contributors and the Possible Root Cause

It has been more than two years since long COVID manifested, and scientists are still far from settled on its cause.

However, based on common clinical manifestations and emerging research, clinicians have identified several contributors to long COVID symptoms.

Spike Protein Appears to Be the Leading Contributor

Spike protein can exist in the immune cells of long COVID patients for up to 15 months after infection.

The spike protein sits on the surface of the COVID-19 virus and is the key to breaking into cells and causing the virus to spread in organs and tissue.

An increasing number of studies are pointing to it (1, 2) as a contributing factor to long COVID.

Studies in mice and human cell cultures revealed that the spike protein could travel into the brain by bypassing the blood-brain barrier.

Autopsy reports on people who died from COVID-19 have found spike protein in the brain, heart, pancreas, liver, kidney, thyroid, reproductive organs, adrenal glands, lungs, nasal and oral cavities, blood, fat, bone, muscle, skin, and even the eyes.

However, the symptoms and laboratory test results vary depending on the patient. Clinicians have therefore developed various hypotheses on the reasons behind these symptoms.

1. Inflamed Immune Cells and Blood Vessels

The spike protein contributes to pathologies. The primary pathology is inflammation (1, 2, 3).

Inflammation is not harmful if controlled and short-term; it is essential to a person’s immune defense. But in the case of long COVID, inflammation is chronic, and this causes cells to become stressed and damaged.

A significant contributor to long COVID may be inflammation within and of the blood vessels.

When interviewed by The Epoch Times, Dr. Bruce Patterson, a viral pathologist and the CEO and founder of IncellDx, a diagnostic company, and internal medicine physician Dr. Jessica Peatross each pointed out the relationship between inflammation and long COVID.

Peatross voluntarily surrendered her medical license in November 2022 to the Medical Board of California due to facing disciplinary actions for approving two vaccine exemptions—one for a child with severe eczema and asthma, and one for a child who had previously experienced side effects to vaccines, according to Peatross’s own statement.

She pointed to studies on acute COVID as a systemic disease driven by inflammation of the lining of the blood vessel walls.

Patterson found spike protein in long COVID patients’ non-classical monocytes. Non-classical monocytes are immune cells. They can attach to blood vessel walls and cause inflammation.

Patterson’s other studies have found high levels of cytokines in long COVID patients’ blood, indicative of inflammation, particularly vascular inflammation.

Inflammation of blood vessels can reduce blood flow to tissues and organs, causing pain and impaired organ function. Low blood flow also means fewer nutrients are supplied to the cells, causing fatigue and weakness.

Unsurprisingly, significant symptoms of inflammation in blood vessels are fatigue, and joint and muscle pain, which overlap with long COVID symptoms.

Symptoms vary depending on where the inflammation occurs.

Vascular inflammation in the superficial layers of the skin may cause clusters of red dots, bruises, or hives.

Inflammation in blood vessels that supply the eyes may cause the eyes to become sensitive to light or even cause vision impairment.

2. Mitochondrial Dysfunction

California physician Dr. Jeffrey Nordella told The Epoch Times that mitochondrial dysfunction is another major contributor to long COVID symptoms.

It should be noted that all of the symptoms, from inflammation to mitochondrial dysfunction, can overlap. Mitochondria can become stressed from low oxygen due to blood vessel inflammation or nearby inflammation.

Mitochondria are present in practically all cells in the body. Mitochondria make energy for the cell by concurrently burning fuel—carbohydrates, proteins, and fats—and consuming oxygen. However, this process can also produce toxic oxygen species that are highly reactive and damaging to mitochondria.

These oxidants must be immediately neutralized, but in the case of many long COVID patients, this is often not resolved quickly enough.

Common long COVID symptoms, like fatigue and dyspnea, then appear. In laboratory studies, cells exposed to spike protein led the mitochondria to become dysfunctional and stressed (1, 2). This would impact mitochondrial energy output.

A recent study on long COVID patients suggested that mitochondrial dysfunction may cause fats to be poorly metabolized for energy needs. The authors found that many of the study’s participants had fatigue, brain fog, and dyspnea; all had high lipid levels, suggesting poor lipid breakdown and utilization.

Interestingly, these patients had both low protein and carbohydrate-related substances in their blood. This pattern is also seen in type 2 diabetes. At the same time, weight gain and an increased risk of developing metabolic diseases have been documented in post-COVID patients.

3. Inflammatory Allergic Response

Mast cells, which are involved in allergies, may contribute to long COVID symptoms.

Mast cells are highly reactive, like many immune cells. They carry ACE2 receptors, which allow entrance to the virus or spike protein. Once activated, mast cells can send vast amounts of histamine and inflammatory cytokines into circulation.

A 2021 study that surveyed 136 long COVID patients about their laboratory test results showed that over 30 percent had high biomarkers that may be indicative of mast cell problems. These patients had high histamine and prostaglandin levels, which are often elevated in people with mast cell problems.

Histamine can cause an increase of cytokines, which can contribute to the cytokine storm and endothelial inflammation present in acute COVID.

Histamine also causes many allergic symptoms, leading to swelling, redness, pain, and fever in the regions of its release.

High histamine levels can bring about itching, abdominal cramps, and even brain fog. If concentrated in the heart muscles, histamine may also contribute to rapid heart contractions, causing arrhythmias and tachycardia.

Many of these symptoms overlap with long COVID symptoms.

Mast cell disorders have also been associated with postural orthostatic tachycardia syndrome, commonly known as POTS. Research shows that 2 to 14 percent of long COVID patients report POTS symptoms of lightheadedness, fainting, and rapid heartbeat upon standing up.

Psychiatrist Dr. Adonis Sfera, who has led several studies on COVID-19, said that there might be shared pathways between long COVID and mast cell disorders.

Some studies have shown that COVID-19 patients on drugs that block mast cell activation did better than patients who were not on such drugs.

An example Sfera gave is the antihypertensive drug losartan. The drug works by blocking ACE2 receptors and lowering histamine activation. COVID patients who took this drug had a lower risk of death from COVID-19 early in the disease than patients who did not.

4. Gut Dysbiosis

Gut dysbiosis, an imbalance of the microbes in the gut, has been extensively documented with long COVID, sometimes occurring for several months (1, 2, 3).

Gastroenterologist and CEO of Progenabiome Dr. Sabine Hazan runs a research lab and conducts fecal tests for long COVID patients.

She found that these patients carried COVID-19 genetic material in their guts months after the initial infection. Their gut microflora would be in a state of imbalance called dysbiosis.

Dysbiotic guts can lead to gastrointestinal symptoms such as diarrhea, constipation, bloating, abdominal pain, and indigestion.

Gut dysbiosis is also associated with chronic diseases such as poor mental health, obesity, diabetes, cancer, and cardiovascular disease.

The gut plays a critical role in physical well-being. A consequence of gut dysbiosis is the breakdown of the gut barrier (a condition called “leaky gut”). Bacteria can leave the gut and enter the bloodstream, leading to an immune response.

Sfera said that many bacteria in the gut are similar in structure to the body’s own cells. So when the immune system attacks bacteria, it may also mistake healthy tissues for bacteria, triggering an “autoimmune inflammation, in which the body attacks itself.”

Autoimmune diseases associated with gut dysbiosis include Lupus, rheumatoid arthritis, ankylosing spondylitis (arthritis of the joints and ligaments of the spine), and inflammatory bowel disease, all of which have been reported after a COVID infection.

Some Reported Symptoms May Not Be From Long COVID

Patterson’s studies on cytokines suggest that many people who report “long COVID” symptoms may not be experiencing long COVID but rather a reactivation of latent viruses.

Studies have shown that infection with COVID-19 can cause dysregulation and suppression of the immune system (1, 2).

When the body’s immune system becomes dysregulated, viruses and infections—such as herpes and Lyme disease—that had been under control may suddenly develop as opportunistic infections.

A patient, Mary Lee, had been experiencing long COVID symptoms since December 2021.

Her cytokine test revealed elevated cytokine levels with results indicating long COVID. However, a subsequent blood test showed that she was also positive for Lyme disease.

Elevated cytokines have been observed with both long COVID and Lyme disease. The diseases have similar symptoms, including headache, fatigue, joint pain, and brain fog, amongst others.

Lee has been suffering from migraines and fatigue for many years. She suspects that her untreated Lyme disease contributed to developing long COVID.

The cause of long COVID is far from settled, and a great deal of the evidence clinicians use to support their hypotheses is anecdotal. Given its complicated clinical symptoms, research will likely continue for many years.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

**************************************************

Tuesday, January 03, 2023



Once-favored Covid drugs ineffective on Omicron may be putting millions at risk

The lack of specialized Covid-19 treatments for people with weak immune systems has left millions of Americans with limited options if they get sick as the pandemic heads into an uncertain winter.

Once heralded as game-changers for Covid patients considered at risk for getting seriously ill — one was used to treat then-President Donald Trump in 2020 — monoclonal antibodies are now largely ineffective against current Covid variants. Easier-to-administer antiviral drugs, such as Paxlovid, have largely taken their place but aren’t safe for all immune-compromised people because they interact with many other drugs.

But the federal government funding that drove drug development in the early days of the pandemic has dried up, and lawmakers have rebuffed the Biden administration’s pleas for more. Without that, there’s little incentive for drugmakers to work on new antibody treatments that could be more effective.

And without a government program like Operation Warp Speed to develop second-generation vaccines and treatments, at-risk patients could be in danger of developing severe cases of Covid and flooding hospitals when the U.S. health care system is already strained, thanks to an influx of patients with an array of respiratory illnesses, including flu and RSV.

“Just because we have exited the emergency phase of the pandemic does not mean that Covid is over or that it no longer poses a danger,” said Leana Wen, a public health professor at George Washington University and former Baltimore health commissioner. “There are millions of Americans who are vulnerable to severe illness.”

The FDA pulled authorizations for four antibody treatments in 2022 as Omicron and its myriad subvariants wiped out their effectiveness. The treatments were geared toward adult and pediatric patients with mild-to-moderate Covid who were considered at risk of developing severe disease and ending up hospitalized.

While antiviral pills are plentiful and remain an option for some with weak immune systems, they won’t work for everyone — Pfizer’s Paxlovid interacts with many widely prescribed drugs.

Monoclonal antibodies — which have been made by companies like Regeneron, Eli Lilly and Vir — are lab-created molecules designed to block a virus’ entry into human cells. But they must bind to the virus’ spike protein to neutralize it, and the coronavirus’ many mutations since its 2019 emergence have gradually rendered the available products ineffective.

“It’s a bit risky to develop this,” said Arturo Casadevall of the Johns Hopkins Bloomberg School of Public Health, pointing to how quickly some Covid variants have surfaced before quickly receding.

A massive spending bill that lawmakers passed before Christmas left out the administration’s $9 billion request for more money to fight the pandemic, meaning there are fewer dollars to be spread around to address emerging Covid needs.

“Due to congressional inaction and a lack of funding, HHS does not have the resources it needs to fund the development of new treatments, and we could find ourselves with a very limited medicine cabinet at a time when we need more tools to combat Covid-19,” a department spokesperson told POLITICO, adding that HHS is working with providers and other groups “to ensure that Americans are able to take advantage of all available treatment options.”

The Biden administration has strongly promoted oral antiviral regimens like Paxlovid, which debuted a year ago and marked a turning point in managing the virus for most Americans.

Immunocompromised individuals — who are either born with immune-suppressing conditions or acquire them after organ transplants or by taking certain drugs — also may not mount sufficient immune responses after vaccination, making treatment options like antibody therapies a critical tool for them.

A CDC alert issued Dec. 20 to clinicians and public health professionals warned of the lack of viable monoclonal antibody treatments — including the diminished efficacy of a prophylactic antibody, Evusheld — and the availability of the antiviral options that to date have seen lackluster uptake. The agency urged providers to consult the National Institutes of Health’s Covid treatment guidelines for ways to potentially manage drug interactions with Paxlovid, such as temporary pauses or reductions in dose.

Remdesivir, an antiviral administered intravenously, is another treatment option for the immunocompromised, but it requires infusions over three days in either hospital or outpatient settings. HHS is urging states to support its health departments and systems in setting up infusion clinics to expand access to remdesivir, especially on an outpatient basis, and is working with maker Gilead to broaden the types of providers eligible to buy the drug.

Covid convalescent plasma remains an option for immunocompromised people who contract the virus, but its availability is scattershot across the country, Casadevall said. The treatment has pros and cons, he said — it’s less likely to be defeated by any one variant and can adapt to different strains, but it’s difficult to administer and requires blood-typing to be done for the recipient.

Still, Casadevall said, the main issue is educational because its use has changed since the pandemic’s early days, when treatments were scarce. Some hospital systems, like Hopkins, use it routinely, while some doctors don’t know plasma is still an option, he said.

The FDA has authorized the emergency use of convalescent plasma containing high Covid antibody levels for immunocompromised patients. But NIH has remained neutral on the treatment in that population, which Janet Handal, president of the Transplant Recipients and Immunocompromised Patient Advocacy Group, says has led to some hospitals balking at administering it.

NIH spokesperson Renate Myles pointed to the agency’s treatment guidelines for Covid, which are developed by an expert panel.

The recommendations for Covid convalescent plasma, last updated on Dec. 1, say there’s “insufficient evidence” to recommend for or against the treatment’s use in immunocompromised patients, while noting some panel members would use plasma to treat an immunocompromised person “with significant symptoms attributable to COVID-19 and with signs of active [viral] replication and who is having an inadequate response to available therapies.”

“In these cases, clinicians should attempt to obtain high-titer [Covid convalescent plasma] from a vaccinated donor who recently recovered from Covid-19 likely caused by a … variant similar to the variant causing the patient’s illness,” the guidelines say.

Casadevall, who leads the Covid-19 Convalescent Plasma Project, says NIH’s stance on plasma is inconsistent with its previous recommendations of monoclonal antibodies, which were made without clinical efficacy data, since Covid antibodies are the active component in both therapies. He led a petition earlier this month — signed by several doctors, including past and current presidents of the Infectious Diseases Society of America — asking NIH to change its recommendations.

Handal’s group also has asked the NIH and the White House to convene a meeting with scientists on the issue.

“To just not be having a dialogue about it is infuriating to us,” Handal said. “People are dying while people are just going through this bureaucratic dance.”

The FDA and European Medicines Agency held a virtual workshop this month to bring doctors, industry and regulators together to discuss supporting novel monoclonal antibody treatments.

“The FDA is committed to working with industry sponsors to expedite the development of new drug products to meet unmet needs, such as the need for new preventive therapies for immune-suppressed patients who are unlikely to respond to vaccination,” an agency spokesperson said.

In the meantime, Regeneron spokesperson Tammy Allen said the company, whose antibody cocktail’s use was limited in January, is committed to evaluating antibody treatment options as the coronavirus evolves.

“We believe monoclonal antibodies have played an important role in the COVID-19 pandemic to date and may again in the future, particularly among people with immunocompromising conditions,” Allen said.

Vir, which partnered with GSK on sotrovimab, continues to study whether the treatment could work against emerging variants and is also evaluating next-generation antibodies and small-molecule therapies, said spokesperson Carly Scaduto.

Still, pharmaceutical companies may be more inclined — both financially and practically — to pursue developing better antiviral pills that pose fewer drug interactions and are easier to administer, said Jason Gallagher, a clinical pharmacy specialist in infectious diseases at Temple University Hospital. Antivirals also hold up better against an ever-changing virus, he added.

“There’s way more money in Paxlovid than there is in any monoclonal” antibody treatment, Gallagher said, and it may take incentives to drugmakers to encourage their development. “They’re not going to make anyone really rich.”

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Infection Fatality Rate of COVID-19 Was 0.0003 Percent At 0–19 Years: Study

A study that looked into the age-stratified infection fatality rate (IFR) of COVID-19 among the non-elderly population has found that the rate was extremely low among young people.

“The median IFR was 0.0003 percent at 0–19 years, 0.002 percent at 20–29 years, 0.011 percent at 30–39 years, 0.035 percent at 40–49 years, 0.123 percent at 50–59 years, and 0.506 percent at 60–69 years,” the study conducted across 29 countries stated. “At a global level, pre-vaccination IFR may have been as low as 0.03 percent and 0.07 percent for 0–59 and 0–69-year-old people, respectively.”

The study aimed to accurately estimate the IFR of COVID-19 among non-elderly populations in the absence of vaccination or prior infection.

For every additional 10 years in age, the IFR was observed to increase by roughly four times. After including data from nine more nations, the median IFR for 0–59 years came in at 0.025 to 0.032 percent and for 0–69 years was at 0.063 to 0.082 percent.

According to the study, the analysis suggests a “much lower” pre-vaccination IFR in the non-elderly population than had been suggested previously. The large differences found between nations were pegged to differences in factors like comorbidities.

Vaccination Dangers Among Youth

A recent study that analyzed children between the ages of 5 and 17 who had received Pfizer COVID-19 shots found an elevated risk of heart inflammation among children as young as 12 years old.

Myocarditis and pericarditis met the threshold for a safety signal for children aged between 12 and 17 following the second and third doses. These heart conditions can cause long-term issues and even death.

“The signal detected for myocarditis/pericarditis is consistent with published peer-reviewed publications demonstrating an elevated risk of myocarditis/pericarditis following mRNA vaccines, especially among younger males aged 12-29 years,” the researchers said.

In an interview with Fox News back in January, MIT researcher Stephanie Seneff had said that it was “outrageous” to give COVID-19 vaccines to young people as they have a “very, very low risk” of dying from the infection.

When looking at the potential harms of these vaccines for children, they don’t make “any sense,” she added. With repeated boosters, such treatment will be “devastating” in the long term.

Parents should do “absolutely everything they can” to avoid getting their children vaccinated against COVID-19, the research scientist advised.

Vaccinating Children

Some countries have stopped their COVID-19 vaccine programs for children. In October, the Swedish Public Health authority ceased recommending vaccination for 12- to 17-year-olds except under special circumstances. The agency acknowledged that very few healthy children have been affected seriously by the virus.

“Overall, we see that the need for care as a result of COVID-19 has been low among children and young people during the pandemic, and has also decreased since the virus variant omicron began to spread,” Soren Andersson, head of a unit at the Public Health Authority, told broadcaster SVT at the time. “In this phase of the pandemic, we do not see that there is a continued need for vaccination in this group.”

Meanwhile in the United States, the Food and Drug Administration (FDA) is pushing ahead with vaccinating children, allowing emergency clearance of vaccines from Pfizer and Moderna for children as young as just six months old.

Data from the U.S. Centers for Disease Control and Prevention (CDC) shows that it is the vaccinated population that made up most of the COVID-19 deaths in August.

During that month, 6,512 deaths were recorded, of which 58.6 percent were attributed to vaccinated or boosted individuals. Back in January, COVID-19 deaths among the vaccinated and boosted had only made up 41 percent of the total mortalities.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Monday, January 02, 2023



Farewell 2022: the year of vindication for Covid skeptics

If 2020 and 2021 were a living nightmare, 2022 was the beginning of the awakening. After two years of being labelled every name under the sun, the time has finally arrived when the dissidents can say that they were right, in large part due to information being released by Elon Musk.

On the Covid front, the initial criticisms about vaccines appear sound. Statistically, they are some of the most ineffective and inefficient vaccines released to market with side effects that many consider unacceptable, especially to children. The full extent of the health risk they pose is not yet known.

A recent study undertaken on over 260,000 individuals in the State of Indiana demonstrated that vaccinated individuals are 2-3 times more likely to be infected with Covid than unvaccinated individuals with natural immunity (from prior infection), a concern that was dismissed as conspiracy.

Natural immunity, initially discounted and laughed at, has won out against Covid vaccines for re-infection, particularly regarding new mutations. ‘Conspiracy theorists’ have been saying this all along, including those in the medical profession.

One of the starkest admissions of the year came from Pfizer executive Janine Small, president of international developed markets. It came in response to a question raised by Dutch Member of the European Parliament Rob Roos: ‘Was the Pfizer Covid vaccine tested on stopping the transmission of the virus before it entered the market?’

Small answered:

‘Did we know about stopping immunisation [sic: should read transmission] before it entered the market? No … we had to really move at the speed of science to really understand what is taking place in the market.’

Her answer presented an admission that the vaccine Pfizer manufactured was initially never tested to see if it prevented transmission, yet prevention of transmission was the premise on which governments and unelected bureaucrats justified arbitrary Covid measures, including lockdowns and vaccine mandates.

Remember when medical authorities told us that we needed to get vaccinated to keep everyone else safe? Remember when they said that if we didn’t take the vaccine we were literally killing grandma? That was all based on (at best) debunked guesswork and (at worst) a fabrication. Our health representatives and government ministers did not know if the vaccine prevented transmission when drafting health directives. And, as it turns out, it never did.

While most mandates have since been dropped, some remain in place, despite being completely devoid of logic or reason. Those who were forced to take the vaccine have been left duped. Many have come to regret taking it, venting their frustration on the (now liberated) social media platform Twitter. Others who had their first two or three doses have sworn off getting any further doses, a declaration that is reflected in low fourth and fifth dose figures.

The vaccines have also been side-eyed in connection with an increase in heart conditions, including myocarditis. The Therapeutic Goods Administration (TGA) knew this early on, and has quietly pulled the Moderna vaccine off the market in Australia months behind other countries. What was the reason for this delay?

Former MP and vaccine advocate Dr Kerryn Phelps recently revealed that she and her partner both suffered significant neurological side effects after taking the Pfizer vaccine. Phelps noted these adverse effects were reported to the TGA. Phelps subsequently claimed that her concerns were never followed up, although the TGA have not commented. She also raised concerns that doctors have been prevented from speaking up about adverse effects presenting in their patients due to fears of being reprimanded.

Failure to live up to transmission claims and ongoing investigations into the #DiedSuddenly medical phenomenon of statistically significant unexplained deaths, is only the beginning of what is increasingly being dubbed a scandal.

Tech billionaire Elon Musk, who has traditionally sat slightly Left of politics, emerged as the unlikely unmasker of Big Pharma.

Some joke that Elon Musk paid $44 billion just to blow the whistle on the absolutely horrifying actions of Twitter under its previous management. Detailed were the complex entanglements with federal agencies that formed a web of genuine collusion to the detriment of free speech and undermined the sanctity of free and fair elections.

Over the past couple of months, Elon has enlisted several independent journalists to help release inside information from the Twitter archives. This has included the dissemination of private conversations between Twitter employees and government officials. Also released were email correspondence and evidence of conversations with federal agencies including the Federal Bureau of Investigation (FBI), the Department of Homeland Security (DHS), the office of the Director of National Intelligence (DNI), and ‘Other Government Agencies’ (eg. the CIA), and evidence of conversations with the government.

These are known as The Twitter Files.

What has come to light thus far has demonstrated that Twitter was actively working with the government and federal agencies to potentially violate the First Amendment rights of Americans who chose to speak out against the accepted narrative. We have been shown, in considerable detail, how Twitter executives, including former head of Trust and Safety Yoel Roth and former head of Legal and Policy Vijaya Gadde, made critical decisions that former CEO Jack Dorsey may not have even been aware of. The tools they used to censor and silence individuals, in particular Conservative accounts, have been confirmed as real despite former Twitter spokespeople denying their existence.

These revelations have highlighted a number of truths that were cast off as ‘conspiracy theories’.

Alex Berenson, who was skeptical of the Covid vaccine, was specifically targeted by the Biden administration, who put pressure on Twitter to take action on his account among other ‘anti-vaxxer accounts’. This ultimately led to his suspension. Only after bringing a lawsuit against Twitter did Berenson have his account restored.

According to the Atlantic:

This was not the end of the drama, though. Last week, Berenson published a Substack post that included screenshots of a conversation on Twitter’s internal Slack messaging system from April 2021, obtained during the course of the lawsuit. The images show employees discussing a recent White House meeting at which members of the Biden administration were said to have posed a “really tough question about why Alex Berenson hasn’t been kicked off from the platform,” as one Slack message put it. Another alleges that Andy Slavitt, who was at the time a senior adviser to Joe Biden on the administration’s COVID-19 response, specifically mentioned a “data viz that had showed [Berenson] was the epicenter of disinfo.”

Berenson has since declared that he will sue the Biden administration for infringing upon his free speech by compelling Twitter to take action against his account.

Once again, legal experts say that his case is unlikely to succeed. Berenson faces a “very high bar” in proving that a private company behaved as a state actor, Evelyn Douek, an Atlantic contributor and assistant professor at Stanford Law School, told me. According to both her and Goldman, the Slack messages that Berenson published don’t amount to proof that the government pressured Twitter to remove Berenson’s account. But Douek is generally perturbed by the evidence of informal pressure by government officials to constrain speech. “It does strike me as unusual,” she said. “It’s certainly unusual to get records of it.”

Other medical experts were targeted, including Harvard Medical School epidemiologist Dr Martin Kulldorff, who tweeted that vaccines should only be taken by those who were most at risk, including the elderly and their care-takers, and that children and those who had already been infected should not have it. His tweet was hit with a ‘misleading’ label.

Dr Andrew Rostom, a Rhode Island physician, was permanently suspended for ‘misinformation’, including a tweet referring to a peer-reviewed study on mRNA vaccines. Other accounts that pointed out the truth on the matter of Covid and vaccines were also hit with ‘misleading’ labels, even if they were merely tweeting findings released by the CDC.

As we move into 2023, more revelations will come to light and the ‘conspiracy theorists’ will likely continue to be proven right over and over again.

While it would be easy to look back on this year as one giant ‘I told you so’, it would be better to take heed of what we have learned and use it as justification to push back against those who would wish us to just move on with our lives as if none of it happened. Yes, these revelations are a good thing, but I cannot help but feel as if this conversation is not over yet.

We cannot become complacent about past abuses because the truth is finally coming out. We must continue to pursue that truth and ensure that it is spread far and wide, if only to ensure justice for all those who have been wronged.

2022 was the year of vindication. 2023 must be the year of accountability. The tangled web of darkness that has been constructed around The Science must be eradicated for good and never allowed to be rebuilt again.

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The Cult of Masked Schoolchildren

There is still some pressure on kids to wear masks in school. Some private schools have gone beyond cloth-masking and mandated N95 (or equivalent) masks for children as young as 4. The Berkeley Unified School District in California recently began transitioning students to N95-level masking. This isn’t a matter of protecting children, their teachers, or their grandparents; it’s delusional and dangerous cultlike behavior.

The way to reduce scientific uncertainty when it comes to practices like masking young children is to conduct randomized studies. When it comes to masking kids in schools, the global scientific community has launched no such studies during the pandemic. The U.K. government commissioned a report on the efficacy of masks in school settings, which failed to identify any clear evidence in favor of this practice. Moreover, the authors write:

Wearing face coverings may have physical side effects and impair face identification, verbal and non-verbal communication between teacher and learner. This means there are downsides to face coverings for pupils and students, including detrimental impacts on communication in the classroom.

Let’s start with cloth masks, which have been the most common type of facial covering used to cover kids’ faces in school. In the only cluster randomized trial conducted during the pandemic among adults, cloth-masking failed to improve the primary outcome of COVID cases that were confirmed with a blood test. In an umbrella review I conducted with Jonathan Darrow of Harvard and Ian Liu of the University of Colorado, we concluded that cloth-masking simply doesn’t work. A month later, the former health commissioner of Baltimore told CNN the same:

The United States is uniquely aggressive in masking young kids. Contrary to scientific evidence, the Centers for Disease Control and the American Academy of Pediatrics advise that children as young as 2 should wear masks. Europe has always been more relaxed on this issue, and the World Health Organization advises against masks for kids under 6 and only selectively for kids under 11.

Data from Spain on masking kids is sobering. The figure below shows the R value—a measure of how fast the virus spreads—by age. Spain mandated masks at a specific age cutoff. If masks have a visible effect, we should see a step down in the graph at the age kids start to wear them (i.e., the spread should drop at the age masking begins). But as you can see, there is only a slow, deliberate, upward trend with no steps down. Based on the evidence only, it would be impossible to guess which age groups are wearing masks and which are not.

This simply means that masking was not associated with a large effect in slowing spread. (If you’re curious, kids started to wear masks in this study at age 6.)

Now let’s consider N95 or equivalent masks that are designed to filter a high percentage of particles. To achieve this goal, N95 masks require a snug fit and validation. Notably, there are no approved N95s for kids because these masks have not been subject to validation for young people. All masks sold with this moniker are merely “N95-style” masks thought to be equivalent, possibly. Berkeley and other school districts have mandated them anyway, even though no study suggests the policy can slow the spread of COVID.

What is the goal of masking policy? Does it at least help to “slow” the spread? Pre-vaccine, it made sense to try to delay infection until all those who wished could be vaccinated, the latter being an intervention that does have a demonstrable effect on rates of serious disease and death. While cloth-masking does little if anything to delay infection, universal N95-masking might have indeed been helpful. But does this goal still make sense after vaccines and omicron?

Omicron has shown it is able to infect even vaccinated people relatively easily (even though, yes, vaccines do still appear to protect from severe disease). The fact that omicron is widely spread by vaccinated people, coupled with its rapid rate of spread, means that sooner rather than later we will all be infected—a conclusion shared earlier by Anthony Fauci. But if infection is inevitable for everyone, then it no longer makes sense to wear a mask. Even the most effective mask can’t avert infection; it can only delay it while causing inconvenience, discomfort, and difficulty speaking, all of which are detrimental to the educational and emotional well-being of schoolchildren.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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