Central Venous Thrombosis Of The Brain After Covid Infection And Vaccination

Peter McCullough is a fearless critic of conventional views about Covid and the response to it. So I read his article below with interest and attention. I was however rather confounded to see him claiming that a journal article showed the opposite of what the journal claimed.

The journal clearly claimed that the pathology they studied was vastly much less frequent among people vaccinated against Covid. McCullouch, in contrast, said that the pathology was just as likely to be found in unvaccinated people.

Looking at the raw numbers, however, I think I can follow McCulloch's reasoning. The actual numbers of people with the pathology were very small: 9 cases in the vaccinated group and 6 in the unvaccinated group. That might seem to show the vaccinated group being worse off but it overlooks the size of the populations those groups were drawn from (the denominator). As a PERCENTAGE of their respective populations, the vaccinated group was much better off.

What McCulloch does, however is to reject the denominators given. He thinks that the vaccinated group were much easier to access statistically so no comparable estimates of the denominators were possible. He just looks at the raw number of cases and says that is what matters. I think he has a point -- but the pathology is a very rare one anyway so may not be worth sustained attention

I reproduce the journal abstract below as well as McCulloch's commentary

Proponents of COVID-19 mass vaccination acknowledge that similar disastrous outcomes occur with both SARS-CoV-2 infection and the COVID-19 vaccines (myocarditis, blood clots, neurological problems)

They position a tradeoff and suggest you should risk it with the vaccine in hopes its lower than that of the infection.

Since 94 percent of Americans have had the COVID-19, its water under the bridge for the infection.

Early therapy reduces the invasive systemic manifestations of the illness and markedly reduces hospitalization and death including from complications.

With vaccination its a different story, the full force of engineered Spike protein is felt in the body with each shot and per case, the severity of the side effect is far worse than that with COVID-19.

Tu, et al illustrated this principle while analyzing central venous thrombosis which is a blood clot in the major vein of the brain which is a medical emergency requiring, hospitalization, intravenous or subcutaneous blood thinners, serial imaging, observation and in some cases surgery.

Tu attempted to divide cases by large denominators to minimize risk; that is invalid in safety research since not all cases can be found particularly fatal ones without an autopsy.

The important findings from Tu are in the tables.

Central venous thrombosis after vaccination was a catastrophe with more cases, greater need for therapy, more brain surgery, and higher degrees of neurologic impairment at discharge for those who took the mRNA vaccine.

Under no circumstances could someone accept a blood clot in the brain with the vaccine in the hopes of not getting COVID-19.

That tradeoff is untenable and yet another reason why vaccine promoters have lost trust from a discerning public.

https://principia-scientific.com/central-venous-thrombosis-of-the-brain-after-covid-infection-and-vaccination/

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Incidence of Cerebral Venous Thrombosis Following SARS-CoV-2 Infection vs mRNA SARS-CoV-2 Vaccination in Singapore

Tian Ming Tu et al.

Key Points

Question What is the risk of cerebral venous thrombosis (CVT) after diagnosis of SARS-CoV-2 infection compared with after messenger RNA (mRNA)-based SARS-CoV-2 vaccination?

Findings In this observational cohort study of 62 447 individuals with SARS-CoV-2 infection and 3 006 662 individuals who received mRNA-based SARS-CoV-2 vaccine in Singapore from January 23, 2020, to August 3, 2021, the incidence rate ratio of CVT requiring hospitalization within 6 weeks of SARS-CoV-2 infection was 32 times higher compared with after mRNA-based SARS-CoV-2 vaccination.

Meaning These findings suggest that the risk of CVT after SARS-CoV-2 infection is higher than after mRNA-based SARS-CoV-2 vaccination.

Abstract

Importance Reports of cerebral venous thrombosis (CVT) after messenger RNA (mRNA)-based SARS-CoV-2 vaccination has caused safety concerns, but CVT is also known to occur after SARS-CoV-2 infection. Comparing the relative incidence of CVT after infection vs vaccination may provide a better perspective of this complication.

Objective To compare the incidence rates and clinical characteristics of CVT following either SARS-CoV-2 infection or mRNA-based SARS-CoV-2 vaccines.

Design, Setting, and Participants Between January 23, 2020, and August 3, 2021, this observational cohort study was conducted at all public acute hospitals in Singapore, where patients hospitalized with CVT within 6 weeks of SARS-CoV-2 infection or after mRNA-based SARS-CoV-2 vaccination (BNT162b2 [Pfizer-BioNTech] or mRNA-1273 [Moderna]) were identified. Diagnosis of SARS-CoV-2 infection was based on quantitative reverse transcription-polymerase chain reaction or positive serology. National SARS-CoV-2 infection data were obtained from the National Centre for Infectious Disease, Singapore, and vaccination data were obtained from the National Immunisation Registry, Singapore.

Exposures SARS-CoV-2 infection or mRNA-based SARS-CoV-2 vaccines.

Main Outcomes and Measures Clinical characteristics, crude incidence rate (IR), and incidence rate ratio (IRR) of CVT after SARS-CoV-2 infection and after mRNA SARS-CoV-2 vaccination.

Results Among 62 447 individuals diagnosed with SARS-CoV-2 infections included in this study, 58 989 (94.5%) were male; the median (range) age was 34 (0-102) years; 6 CVT cases were identified (all were male; median [range] age was 33.5 [27-40] years). Among 3 006 662 individuals who received at least 1 dose of mRNA-based SARS-CoV-2 vaccine, 1 626 623 (54.1%) were male; the median (range) age was 50 (12-121) years; 9 CVT cases were identified (7 male individuals [77.8%]; median [range] age: 60 [46-76] years). The crude IR of CVT after SARS-CoV-2 infections was 83.3 per 100 000 person-years (95% CI, 30.6-181.2 per 100 000 person-years) and 2.59 per 100 000 person-years (95% CI, 1.19-4.92 per 100 000 person-years) after mRNA-based SARS-CoV-2 vaccination. Six (66.7%) received BNT162b2 (Pfizer-BioNTech) vaccine and 3 (33.3%) received mRNA-1273 (Moderna) vaccine. The crude IRR of CVT hospitalizations with SARS-CoV-2 infection compared with those who received mRNA SARS-CoV-2 vaccination was 32.1 (95% CI, 9.40-101; P < .001).

Conclusions and Relevance The incidence rate of CVT after SARS-CoV-2 infection was significantly higher compared with after mRNA-based SARS-CoV-2 vaccination. CVT remained rare after mRNA-based SARS-CoV-2 vaccines, reinforcing its safety.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2790206

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Physician Assistant Fired for Reporting COVID-19 Vaccine Adverse Events to VAERS

For her efforts to report injuries to the Vaccine Adverse Events Reporting System (VAERS) and to educate others in her hospital system on doing the same, Physician Assistant Deborah Conrad said she was labeled an anti-vaxxer and fired from her job.

Today, the New York-based Conrad tells her story at medical freedom conferences throughout the country, the most recent being one in Mississippi where physicians, scientists, and the vaccine injured warned state lawmakers to pull the COVID-19 vaccines from the market.

Conrad told The Epoch Times she began to see early danger signals in 2021 upon the vaccine rollout, and with that, resistance among her colleagues to report on them.

“After the vaccines came out, there was this uptick in unusual symptoms, some of which I had never seen in my 20-year career,” Conrad said. “In every case, it was in somebody who had received the COVID-19 vaccine.”

Conrad said she had never admitted an adult patient with RSV (respiratory syncytial virus) until the COVID-19 vaccines. “And every patient who came in with RSV was vaccinated for COVID,” Conrad said. “It wasn’t normal.”

Then, there were the adolescents with no previous medical conditions who had gotten the COVID-19 vaccine a week prior and, suddenly, they were struck with pneumonia and not able to function, she said. “They weren’t able to walk or eat, and they were completely and totally fatigued,” Conrad said.

This was in 2021 before myocarditis was being discussed, so many of those early cases that were probably myocarditis were diagnosed as pneumonia, she said.

“A lot of these myocarditis cases came in with fevers because of this massive inflammatory response that was taking place in the body, so they would be labeled as septic, treated as if we were treating pneumonia or fevers of unknown origin,” Conrad said. “We’d treat them with antibiotics and all sorts of other things, not realizing that they were having heart failure.”

Conrad began reporting to VAERS, which she said was an overwhelming task not made easy by its multiple user-interface complications. “My entire life had been taken over by doing these VAERS reports by myself,” she said.

In meetings with leadership, she would propose implementing a reporting system and hiring someone to manage the reports, she said.

‘A Hostile Environment’

“They kept telling me we’re looking into it and we’ll get back to you,” Conrad said. “Around April 2021, leadership came back and said no one else is reporting injuries—implying that I was crazy and there was nothing really going on with the vaccines.”

Leadership then audited her reports, she said and concluded that she was overreporting.

“I was then told that by doing VAERS reports and even discussing VAERS that it was an admission that the vaccines were unsafe, so it’s contributing to vaccine hesitancy,” Conrad said.

From there, it became a “very hostile environment” that compelled her to seek legal counsel, who wrote letters to the Department of Health, the CDC, and the FDA.

“No one cared,” Conrad said. “Finally, I had had it. It was so unethical; I couldn’t take it anymore. These VAERS reports are critical to assuring these vaccines are safe for us all. I could no longer be a part of a system that is lying to the American people.”

Conrad decided to become a whistleblower, telling her story on Del Bigtree’s The Highwire, knowing, she said, that it would cost her job.

“I couldn’t remain silent, even if it meant losing my career and everything I worked for,” she said. “I was fired a few weeks later and walked out like a criminal in front of all my peers.”

The initiative and education she had brought forth to report to VAERS were squashed that day, she said.

According to Barbara Loe Fisher, co-founder and president of the National Vaccine Information Center (NVIC), under the National Vaccine Injury Act of 1986, it’s a federal requirement for health care workers to report vaccine-related adverse events to VAERS.

Fisher, whose son was harmed by the DTP vaccine in 1980, worked with other parents of vaccine-injured children in establishing the NVIC in 1982.

“The 1986 Act was driven by parents of DPT vaccine injured children asking the government to pass legislation to secure vaccine safety informing, recording, reporting, and research provisions in the vaccination system to make it safer, and to create a federal compensation system alternative to a lawsuit against manufacturers of vaccines that injure or kill children,” Fisher told The Epoch Times.

In addition to NVIC arguing that physicians and vaccine manufacturers should be giving informed consent and report injuries, the organization maintained they should also continue to be held accountable in a civil court to serve as an incentive for physicians to administer vaccines responsibly, for manufacturers to produce safer vaccines, and for adequate federal compensation to vaccine-injured children.

“The vaccine manufacturers responded to our call for federal legislation reforming the vaccination system by threatening to leave the US without childhood vaccines unless the government gave them a blanket liability shield for harm caused by vaccines, arguing that if the FDA licensed a childhood vaccine as ‘safe,’ and the CDC recommended the vaccine for universal use by all children, and the states mandated the vaccine for daycare and school entry, then the vaccine manufacturer should not be held liable for harm caused by the product,” Fisher said.

When the Act passed, physicians were still liable for medical malpractice claims and pharmaceutical companies remained liable for product design defect claims in civil court, Fisher said.

“Unfortunately, the 1986 Act looks nothing today like when it was passed in 1986,” Fisher said. “In 1987, Congress passed an amendment to give a liability shield to doctors and vaccine providers. Over the next decades, amendments were added that weakened or eliminated safety provisions and the ability of children to receive federal compensation.”

In 1990, VAERS was launched; however, Fisher said, there are no legal consequences for a doctor’s failure to file a report.

“That’s because Congress made it a federal requirement in the 1986 Act to report but did not include legal penalties when vaccine companies or vaccine providers fail to report,” Fisher wrote.

‘A Prescription for Tyranny’

In 2011, amid hundreds of lawsuits linking autism to vaccine injuries, Fisher said the U.S. Supreme Court ignored the legislative language and reasons for the 1986 Act when it shielded vaccine manufacturers from all civil liability for vaccine injuries and deaths.

The federal government had sided with Big Pharma, Fisher said.

“At this point, those of us who worked on the 1986 Act with Congress know that our trust was betrayed by politicians who made backroom deals with drug companies, medical trade organizations, and federal agencies to gut the Act after it was passed and give the pharmaceutical industry what it wanted in 1986 and could not get: a complete liability shield for vaccine injuries and deaths,” Fisher said.

The 2011 case—Bruesewitz v. Wyeth—centered around the parents of Hanna Bruesewitz, who alleged their daughter’s neurological problems were caused by a vaccine made by Wyeth, which was a Pennsylvania pharmaceutical company before it consolidated with Pfizer.

The 1986 Act established a vaccine court to confirm vaccine injuries and award damages. After losing in the vaccine court, the Bruesewitz family brought the case to the highest court.

Marcia Coyle with The National Law Journal told PBS NewsHour in 2011 that there were only eight Justices presiding over the case because Justice Elena Kagan had recused herself due to her involvement as Solicitor General of the United States representing the federal government on the case.

“The Obama administration is supporting Wyeth laboratories saying that this lawsuit is barred,” Coyle said. “So, there are eight Justices. There could have been seven. The Chief Justice [John Roberts] had recused himself in the initial stages because he owns stock in Wyeth and he sold the stock in order to participate now.”

The pharmaceutical companies’ entanglement with federal officials wasn’t what Fisher said she would call an example of public health.

In a 2011 commentary on the ruling, she said, “This is exploitation of a captive people by a pharmaceutical industry seeking unlimited profits and by doctors and physicians of authority who have never seen a vaccine they did not want to mandate. It is a drug company stockholder’s dream, a health care consumer’s worst nightmare, and prescription for tyranny.”

In the wake of the decision, the 1986 Act seemed to lose its relevance, and the importance of reporting to VAERS became downplayed. Allegations that vaccines caused autism were ridiculed in pop culture’s media campaigns such as magicians Penn and Teller widely shared video promoting the vaccines and shutting down those who questioned their safety while ignoring what groups like NVIC were initially calling for: not the eradication of vaccines but safer vaccines with no mandates.

In retrospect, Fisher said, “Had the Supreme Court upheld the spirit and intent of the Act as originally passed in 1986, we may have been able to hold mRNA COVID vaccine manufacturers liable for design defect in a civil court of law today.”

The COVID-19 vaccines were issued under emergency use authorization, which grants the manufacturers immunity from liability.

‘The Whole System Is Corrupt’

Conrad herself said in her education as a physician’s assistant she never trained to even acknowledge VAERS or adverse events.

“When it came to learning about the vaccines, we learned the basic immunology associated with the vaccines and the adult and childhood schedule, but there’s no discussion on their side effects,” Conrad said. “We go into practice with the idea that vaccines are safe and effective. I never considered otherwise until COVID-19 happened.”

Among the insights the pandemic delivered has been that the unethical relationship between federal officials and the pharmaceutical-industrial complex has been going on much longer than many realize, Conrad said.

“This whole system is corrupt,” Conrad said. “The light in this whole experience for me is that now I’m aware of how deep the lies and corruption really are.”

https://www.theepochtimes.com/physician-assistant-fired-for-reporting-covid-vaccine-adverse-events-to-vaers_5130783.html

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Biden Signs Bill to Declassify COVID Origins Intelligence on Wuhan Lab

President Joe Biden on March 20 signed into law a bill mandating declassification of COVID origin-related intelligence, saying that he shares “Congress’s goal of releasing as much information as possible” on the issue.

“We need to get to the bottom of COVID-19’s origins to help ensure we can better prevent future pandemics,” Biden said in a statement. “My Administration will continue to review all classified information relating to COVID19’s origins, including potential links to the Wuhan Institute of Virology.”

He added that, in implementing the legislation, the administration will “declassify and share as much of that information as possible, consistent with my constitutional authority to protect against the disclosure of information that would harm national security.”

This month, both the Senate and the House unanimously passed the bipartisan bill, dubbed “COVID-19 Origin Act of 2023,” before sending it to Biden’s desk. The bill directs the director of national intelligence to “declassify any and all information relating to potential links between the Wuhan Institute of Virology and the origin” of COVID-19.

Efforts to find out the origin of COVID-19 have consistently met with resistance from China, where the communist regime has covered up cases, silenced whistleblowers trying to sound warnings on the virus’s danger from the onset of the pandemic, and repeatedly refused outside investigators to probe the virus origins.

The Wuhan Institute of Virology has been the center of contention as a suspected source where the virus may have leaked.

https://www.theepochtimes.com/biden-signs-bill-to-declassify-covid-origin-intelligence-on-wuhan-lab_5137128.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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How the West Abetted Beijing’s Censorship of the Lab Leak Theory

“Debunked.” “Dangerous.” “Unhelpful.” These were some of the terms heaped on the theory that COVID-19 might have spilled from a lab in China, accidentally or not. Suggesting the virus may have been linked to a Chinese lab would swiftly earn one the label of “conspiracy theorist.”

That was the case for at least 18 months since the pandemic erupted from China, where the ruling communist regime has repeatedly thwarted efforts by citizen journalists and the outside world to probe the virus origins, and covered up the true death toll.

Three years on, the world is still in the dark about how the pandemic began. But mainstream discussion has gone through an about-face on the lab leak theory. The once-maligned hypothesis has gained significant traction—so much so that the FBI recently sided with the Energy Department in assessing that COVID-19 was “likely” the result of a lab leak.

But for many who have long sounded the alarm on the Wuhan lab, the U.S. government was too late to the game.

“My initial thoughts are where have they been for the last two-and-a-half years?” Rep. Ronny Jackson (R-Texas), who sits on the House Select Subcommittee on the Coronavirus Pandemic, told The Epoch Times’ sister media NTD. “The entire world should have risen up and made China financially responsible for what had happened.”

Censorship

Concerns about the Wuhan lab came on early in the pandemic. At the time when Beijing was still blaming a wet market in the central Chinese city of Wuhan as the virus source, The Epoch Times released a documentary titled “Tracking Down the Origin of Wuhan Coronavirus” drawing attention to the Wuhan Institute of Virology (WIV), which houses a biosafety level 4 facility that had been working on coronavirus research, and—as it was later revealed—highly-risky experiments that could make a virus more lethal.

Across different platforms, that video generated tens of millions of views shortly after its launch.

But rather than allowing further examination of these concerns, an all-out campaign was launched in the United States to shut down discussion of the Wuhan lab’s possible role in spawning the pandemic.

Facebook went on to mark the documentary as “false,” but a key source for the fact-checkers’ claim was not independent: a Singapore-based scientist who herself worked with the Wuhan Institute of Virology and praised the facility’s researchers as “incredibly competent, hardworking, and are excellent scientists with superb track records.”

These statements would later come under doubt as evidence of the lab’s risky experiments and lax biosafety standards came to light. But in 2020, they were enough to trigger a near-blanket media shutdown. Idaho state Rep. Heather Scott, a Republican and a biologist, was ridiculed by local media for sharing the video and getting a fact-check label.

Washington Post in a widely-cited article accused Sen. Tom Cotton (R-Ark.), who called for questions to be asked about the lab, of “repeating a coronavirus conspiracy theory that was already debunked.” It issued a correction in 2021 to remove the word “conspiracy theory,” which it acknowledged was an inaccurate characterization because there was no consensus about COVID origin.

‘Something Was Very Fishy’

As open discussion of the COVID origins was being muzzled in the West, China’s communist party was waging a full-fledged campaign to silence critics of its handling of the pandemic.

Law enforcement reprimanded doctors who sounded an early alarm on the virus, warning them not to “fear monger.” Citizen journalists were imprisoned. Chinese officials and state media, while hailing the communist leadership as exemplary in its global pandemic response, further exploited the rise of anti-Asian attacks in the United States by framing Western criticism of the regime’s handling of the outbreak as racist.

The result was that the world at large echoed narratives from China with little questioning.

But for Hans Mahncke, who has been documenting the U.S. suppression of the lab leak hypothesis for for The Epoch Times for the past two years, his suspicions were aroused as as soon as Chinese authorities took the unprecedented step on Jan. 23, 2020 to lock down the virus ground-zero Wuhan, a city of over 11 million.

“I knew something was very fishy,” he said in an interview, noting that Beijing hadn’t done so when severe acute respiratory syndrome (SARS) broke out from China in 2002, which by official accounts infected thousands worldwide.

“If you’re going to lock down the city, you’re not going to do it for a SARS virus,” Mahncke said, noting SARS’ relatively low transmissibility. This convinced him right then that the Chinese leader Xi Jinping “must have had some extra information, some data point that made him do something very out of the ordinary.”

More evidence soon emerged indicating something was off: the existence of a lab doing coronavirus research in the COVID-19 hotspot; a short Feb. 6 paper by two Wuhan university researchers—taken offline shortly after—pointed to WIV as a possible place where the “killer coronavirus” could have come from; the Wuhan facility’s senior virologist Shi Zhengli had for years been studying SARS-like coronaviruses, on which she published papers as early as 2015.

“I had to sort of bite my tongue a bit because I knew that if you said it publicly, or if you said it too stringently, you would get deleted off of social media,” he said, noting that he had seen friends censored from Twitter for lab leak comments.

“We could not just go into the public and say these things, because immediately you’d either have your Twitter account canceled, you would be shunned, you would get into trouble at work. You’d be called a ‘conspiracy theorist,’ you would have trolls and other people harass you.”

Something clicked for Mahncke as he followed the World Health Organization-backed (WHO) probe in Wuhan in early 2021. The mission, conducted with heavy involvement from the Chinese side, dismissed the lab incident hypothesis as “extremely unlikely.”

But after reading further into the investigators’ background, Mahncke realized that Peter Daszak, the U.S. expert on the WHO task force, had not only worked closely with researchers at the Wuhan lab but was instrumental in stymying discussion of the lab leak hypothethis during the pandemic’s early days.

Over the next months, internal documents released under Freedom of Information Act (FOIA) would show that Daszak had a more than passing friendship with the WIV staff. His New York-based nonprofit, EcoHealth Alliance, funneled hundreds of thousands of taxpayer dollars to the Wuhan lab for virus research, including “gain of function” studies that could make existing pathogens more dangerous.

Anthony Fauci, who recently stepped down as head of the National Institute of Allergy and Infectious Diseases that funded EcoHealth’s projects, initiated a call in early February 2020 after a team of scientists flagged concerns that the virus may have been engineered. Four participants of the teleconference, Daszak included, went on to draft “The Proximal Origin of SARS-CoV-2,” a paper that was widely circulated through media and used by many to assert the primacy of the natural origin theory.

Hitting a Brick Wall

When reports about a virus outbreak in China were first emerging in early January 2020, immunologist Nikolai Petrovsky was at his holiday house in Colorado to escape the blistering heat back at home in Australia.

About a week before Wuhan went into a full lockdown, the WHO was still repeating the Chinese claim that the virus was unlikely to be transmissible between humans. But on Petrovsky’s social media feeds, locals were posting images of dead bodies on stretchers and Chinese police welding apartment doors.

The official Chinese message, and the WHO’s amplification of it, was “outrageous,” Petrovsky, a Flinders University professor specializing in vaccine development, told The Epoch Times.

“I immediately recognized this was a serious virus that wasn’t being treated seriously. And when you don’t treat a serious virus seriously, you end up with a disaster.”

Shelving his vacation plans, Petrovsky began to run supercomputer modeling studies on the COVID viral sequence, hoping to find out which animal the virus came from.

By March, the analysis had yielded something no one in his team was looking for. The virus seemed better adapted to a human cell than any of the potential animal hosts identified.

“So then we said: ‘Well, how could that happen? Either the virus was spreading in humans for years with no one knowing it, which seems highly unlikely,’” he said. “Or, SARS-CoV-2 could have met a human cell in a laboratory dish.”

“It was like a light bulb moment,” Petrovsky said. “To us, it was just an obvious explanation for a finding that we had confirmed.”

As Petrovsky was pondering the lab hypothesis, Daszak was organizing a group of health experts to shut down challenges that the virus isn’t from nature. He was behind a statement co-signed by more than two dozen scientists, including four EcoHealth associates, that appeared in the medical journal Lancet in February 2020, which praised their Chinese counterparts for their “remarkable” efforts to fight the outbreak and sharing results “transparently” with the global health community, and derided alternative theories about the virus origin as “rumors” and “conspiracy.”

Petrovsky was shocked. “Politics should have no role in scientific investigation, and as far as I could see this article was purely about politics, containing no actual factual data,” he said. “Science should be neutral and just about finding the truth. It’s not about whether that truth is politically convenient or not.”

But this political ploy had real-world impacts on Petrovsky pursuing the science: getting his team’s findings published in scientific publications became next to impossible.

“We just hit brick walls,” said Petrovsky. “Several of the big publishers send it back to us in 48 hours without even reviewing.”

It took about a year of appeals and dealing with “very antagonistic reviewers” before prominent science journal Nature agreed to accept their paper. By then the landscape had changed: More scientists were coming forward urging a deeper look into the lab leak possibility, and President Joe Biden, acknowledging the scenario to be plausible, had ordered his intelligence agencies to produce a report on the virus origins within 90 days.

But the damage from the delay was hard to undo.

“By that time, the paper had much less impact,” said Petrovsky, because everyone had been convinced by the highly promoted Nature Medicine commentary that the virus must have had an animal source “and anyone suggesting otherwise, was a conspiracy theorist.”

“It appeared by then they were satisfied that their global disinformation campaign had been so successful at creating a smokescreen that it was now safe to let other data come out figuring everyone would ignore it or just attribute it to a conspiracy theory,” he added.

“And that is exactly how it played out.”

Inside the government, the atmosphere was no less intense. David Asher, who spearheaded a State Department task force probing the COVID origins in 2020, recalled being troubled by the military takeover of the WIV days after Wuhan lockdown. So he reached to the National Institutes of Health (NIH) for expert opinion beginning in late Spring that year.

The NIH’s entanglement with the Wuhan lab wasn’t known at the time. But to his surprise, the institute provided “no investigative file” and pointed him to the Proximal Origin article.

The NIH head at the time, Francis Collins, “told us through their staff, not directly, that we should just trust the Chinese,” Asher, now a senior fellow at the Hudson Institute, told The Epoch Times. “My answer was, ‘If that’s your basis for your analysis, then you have no basis for your analysis.’”

“So they were basically operating in a way that was totally inconsistent with transparency, the truth, and any sort of accountability.”

https://www.theepochtimes.com/how-the-west-abetted-beijings-censorship-of-the-lab-leak-theory_5134112.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Government censorship machine targeted TRUTH

The latest Twitter Files installment focuses on Stanford University’s Virality Project, which federal agencies bankrolled to engage in “detecting and mitigating the impact of false and misleading narratives related to COVID-19 vaccines.” The Virality Project, partnering with other federal contractors, sent weekly “anti-vax disinformation” reports to Twitter and other social media companies.

Mike Benz, president of the Foundation for Freedom Online, notes that the project was “deputized by [Homeland Security] to censor millions of . . . opinions . . . about COVID.”

Missouri Attorney General Andrew Bailey, whose lawsuit is shattering Biden administration coverups, described the program: Federal health officials in the Surgeon General’s Office, the Centers for Disease Control and Prevention and Health and Human Services collaborated in a “censorship enterprise called the Virality Project, which procures the censorship of enormous quantities of First Amendment-protected speech.”

Disinformation warriors worked overtime to suppress “false” claims about the side effects of COVID vaccine, especially the true claims. Since the Food and Drug Administration officially (and speedily) approved COVID vaccines, any reports of side effects were automatically disinformation.

The Virality Project recommended that social-media companies suppress “stories of true vaccine side effects” and “true posts which could fuel [vaccine] hesitancy.” The project “routinely framed real testimonials about [vaccine] side effects as misinformation, from ‘true stories’ of blood clots from AstraZeneca vaccines to a New York Times story about vaccine recipients who contracted the blood disorder thrombocytopenia.”

The FDA now admits that the vaccines can cause strokes in senior citizens; many studies have linked the vaccines to myocarditis in young males.

The Virality Project derided as “misinformation” claims that the vaccines failed to prevent COVID transmission even after the CDC conceded the vaccine’s failure on that score.

Reverence for Washington poohbahs was the key. The Virality Project, Taibbi declares, “was specifically not based on ‘assertions of fact,’ but public submission to authority, acceptance of narrative, and pronouncements by figures like Anthony Fauci.”

In June 2021, a Freedom of Information Act request spurred disclosure of Fauci emails revealing his flip-flops on masks and his kowtowing to the Chinese Communist Party. The Virality Project warned Twitter that the emails were being exploited “to foment increased distrust in Fauci’s guidance and in American public health officials and institutions.”

But it wasn’t cynics’ fault that Fauci proffered disgracefully dishonest claims.

The Virality Project had several federally funded partners, including the Pentagon-funded Graphika. That company sent Twitter a report warning, “This continual process of seeding doubt and uncertainty in authoritative voices leads to a society that finds it too challenging to identify what’s true or false.”

One problem once the government starts censoring: It is never enough. On April 26, 2022, the Virality Project issued a report proposing a “rumor-control mechanism to address nationally trending narratives” and creating a “Misinformation and Disinformation Center of Excellence.” The following day, Homeland Security Secretary Alejandro Mayorkas told Congress he had already created a “Disinformation Governance Board,” headed by the singing censor, Nina Jankowitz. (The Post took the lead in demolishing that board.)

And that’s why we have federal agencies and federal contractors to tell us what to think.

Taibbi concludes, “America’s information mission went from counterterrorism abroad, to stopping ‘foreign interference’ from reaching domestic audiences, to 80% domestic content, much of it true. The ‘Disinformation Governance Board’ is out; but truth-policing is not.”

The fact that the media has largely ignored the Twitter Files revelations proves either that journalists don’t read so good or that they don’t give a damn about free speech. Or both. Is it “disinformation” to ask if anyone in Washington gives a damn about trampling the Constitution?

https://nypost.com/2023/03/17/private-federal-censorship-machine-targeted-true-misinformation/

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Project Veritas Exposes What We've Suspected About the COVID Vaccine

Young Americans are dying all over from cardiac events; at least, that’s what it feels like, but the data support it. Cardiac episodes have spiked in the 18-34 demographic, which began two years ago. I wonder what mass epidemiological event occurred that would spur such a spike in cases of young people dying suddenly. It’s not like there was some vaccine that was rushed to market, protected by a legal shield, which government entities forced down our throats. Oh wait, that was COVID, and millions who refused to get the vaccine were threatened with termination of employment or social ostracization. Well, Project Veritas found documents from Pfizer showing that the vaccine did show that one of the side effects was increased risk of myocarditis (via Project Veritas):

“There is evidence that suggests patients who receive a COVID-19 vaccine are at an increased risk of myocarditis.”

* “Onset was typically within several days after mRNA COVID-19 vaccination (from Pfizer or Moderna), and cases have occurred more often after the second dose than the first dose.” [PAGE 19]

* “The reasons for male predominance in myocarditis and pericarditis incidence post COVID-19 vaccination remain unknown.” [PAGE 28]

* “The pattern of cases conform, as per the label, to a pattern of myocarditis cases occurring in majority of young males below 29 years of age within the first two weeks postvaccination...” [PAGE 19]

* “Since April 2021, increased cases of myocarditis and pericarditis have been reported in the United States after mRNA COVID-19 vaccination (Pfizer-BioNTech and Moderna), particularly in adolescents and young adults (CDC 2021).” [PAGE 18]

* “Myocarditis events were defined as encounters with a billing or encounter diagnosis consistent with an ICD10-CM or SNOMED CT code for myocarditis which fell within two weeks of receiving dose 1, 2, or 3 of the Pfizer COVID-19 vaccine.”

* “Incidence rates of myocarditis were measured for each vaccine dose with denominator signifying the total number of patients receiving that dose and numerator signifying the total number of patients meeting the above criteria for an encounter for myocarditis following that dose.”

https://townhall.com/tipsheet/mattvespa/2023/03/17/project-veritas-n2620814 ?

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Don’t axe QoVax: A priceless biobank with the answers to long Covid is threatened with destruction

Rebecca Weisser

Why has the Queensland health department withdrawn funding for its award-winning QoVax research program studying the safety and efficacy of Covid-19 vaccines?

Only last August, Queensland’s Health Minister, Yvette D’Ath, and the chief operating officer of Queensland Health, Dr David Rosengren, celebrated the work of the QoVax team, led by Professor Janet Davies, which was a highly commended finalist in the Pursuing Innovation category at the 2022 Queensland Health Awards for Excellence.

The prize was no surprise. The program is the creation of 27 highly-skilled researchers, health professionals and administrative service staff with over fifty research, digital, scientific, and clinical skillsets such as laboratory scientists, nurses, solution and enterprise architects, pathologists, molecular and computational biologists, bioinformatician data scientists and infectious disease specialists. They were supported by multiple partners including twelve health service agencies, five universities, and two private pathology services

QoVax was also strongly supported by Queenslanders, rapidly enrolling more than 10,000 participants, both vaccinated and unvaccinated, from 85 per cent of postcodes across the state including communities in regional and Far North Queensland of whom more than 2 per cent identify as Aboriginal and/or Torres Strait Islander.

That level of support didn’t just happen. People from the QoVax team like Josh, an Aboriginal and Torres Strait Islander health worker, and Janette, a registered nurse from Cairns, met with elders and First Nation communities in remote locations. They were accompanied by the Royal Flying Doctors Service who transported blood samples back to the laboratory in Cairns for testing.

Countries like Australia and New Zealand were uniquely placed to investigate vaccine efficacy because their diverse population was, until late in the pandemic, relatively free of the Covid-19 virus. Full marks to Queensland, and Professor Davies, for seizing the initiative. She was conscious from the outset that the Covid vaccine rollout was the largest coordinated vaccination program that had ever been undertaken and she wanted to record and evaluate the experience of Queenslanders.

The QoVax team didn’t just collect the standard data. Participants provided information on environmental and social determinants of health and biospecimens of blood and saliva that have been used to derive genomic, transcriptomic and proteomic datasets that will shed light on how the novel vaccines impact the immune system.

The secure digitally integrated biobank has 120,000 biospecimens: serum, saliva and peripheral blood mononuclear cells, in three -80 degrees Celsius freezers and three liquid nitrogen dewars. The linked data repository has four million linked data points and more than 500 whole genomes.

In addition, the biobank has access to real-time electronic medical records. With 70 per cent of hospitals in Queensland storing medical records electronically, the study was intended to allow long-term digital surveillance of health outcomes related to Covid-19 vaccinations, and intersections between vaccine responses and Sars-CoV-2 infection.

Studying immune responses is a vital part of assessing vaccines and Davies’ work is consistent with similar studies completed on other vaccines but her research is particularly important because two new vaccine delivery platforms were used – modified messenger RNA and viral vector DNA. The multiomic datasets that her team has collected will be critical to deciphering the impact of these platforms on the DNA, RNA and proteins synthesis of the human immune system. This is particularly important because the original trials of these vaccines were meant to last two years but the placebo group was vaccinated after only two months. As a result, there is a shortage of rigorous data adding even more importance to Davies’ research which includes an unvaccinated cohort. The information will allow researchers not just to better understand how the vaccines work but why vaccinated or unvaccinated people get repeat infections, long Covid, severe Covid or indeed die of Covid.

The study and the biobank have enormous international significance. The main comparable study is the UK Biobank but that country had very different early experience with high Covid caseloads prior to the rollout of vaccines.

Already the QoVax team has presented early findings at five conferences. The team was working on next steps to make the QoVax biobank and data repository accessible. The process had begun to scope and develop a user interface through collaborative workshops with researchers and health professionals across Australia.

Yet instead of answering vital questions about why Australia, one of the most highly vaccinated countries in the world, has such high excess mortality, and so many cases of long Covid in vaccinated people, Professor Davies is being forced to close down the QoVax program and sack her staff.

Worse still, the biobank, which should be a resource for the world, is threatened with destruction. Its precious resources will be destroyed in twelve months to save a trivial sum of money. The whole project has cost only $20 million.

Australia usually punches above its weight in medical research with eight Nobel prizes for physiology and medicine. Unfortunately, it also has a reputation for treating its scientists with contempt. Nobel laureates Barry Marshall and Robin Warren were ostracised in Australia for several decades after their amazing discovery of the bacterium Helicobacter pylori and its role in gastritis and peptic ulcer disease by a ‘gastric mafia’, an entrenched coterie of established scientists who refused to accept their findings because the therapeutic implications dented their vested interests.

The value of this data collected by QoVax is incalculable. It is a national scandal that it is not properly resourced. Every Queenslander involved in the project needs to speak up, as does every vaccinated person who has suffered from long Covid, or repeated Covid infections, or has been hospitalised with Covid, as well as every person that has suffered a vaccine injury or death and every person subjected to a vaccine mandate (when the vaccines did not stop transmission of the virus).

https://www.spectator.com.au/2023/03/dont-axe-qovax/

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Emails Reveal Journal’s Internal Discussions Before Rejecting Challenge to Pfizer’s Effectiveness Claim

Officials at a major journal discussed a professor’s alleged anti-vaccine Twitter activity when considering whether to publish his paper challenging the claim that Pfizer’s vaccine was 95 percent effective, newly disclosed emails show.

The Lancet journal ultimately rejected the rebuttal paper.

Professor Norman Fenton “retweeted anti-vaxx posts on Twitter,” one Lancet official wrote to colleagues.

They also discussed “vaccine misinformation” and Fenton’s background, the heavily redacted emails show.

“[redacted] have investigated him a little and he does seem to have a legitimate academic appointment,” one email, titled “Ongoing issues monitoring,” stated.

Fenton, emeritus professor of risk at Queen Mary University of London, obtained the emails from Elsevier, which publishes The Lancet.

“We knew that all the main academic journals were routinely rejecting any articles that were in any way questioning the accuracy of studies claiming vaccine effectiveness or safety. What surprised even us about this case was the sheer nastiness and lack of professionalism displayed by the journal’s editorial staff,” Fenton told The Epoch Times via email.

“The notion that authors’ academic credentials and Twitter activities had to be investigated as part of the reviewing process is shocking,” he added.

The Lancet did not respond to a request for comment.

Effectiveness Claim

The Lancet in May 2021 published a paper from Israeli officials and Pfizer employees that claimed the company’s vaccine was 95 percent effective against COVID-19 infection in Israel from Jan. 24, 2021, to April 3, 2021.

The study analyzed surveillance data drawn from government-funded insurance providers. Pfizer and Israel entered into multiple agreements early in the pandemic that saw the country primarily use the company’s vaccine and share data with the firm.

The study showed that two doses of Pfizer’s vaccine were “highly effective” across all age groups 16 and older in preventing symptomatic COVID-19, asymptomatic COVID-19, and COVID-19-related hospitalization, severe disease, and death, researchers said in the study, which was peer-reviewed before publication.

“These findings suggest that COVID-19 vaccination can help to control the pandemic,” they said.

The study was funded by the Israeli Ministry of Health and Pfizer.

Rebuttal

The effectiveness estimates were exaggerated, Fenton and Martin Neil, a professor of computer science and statistics at Queen Mary of London, wrote in a rapid response to the paper.

That stemmed in part from adjusting for how unvaccinated people were routinely tested for COVID-19 while vaccinated people were not, the professors said.

“There is also failure to properly adjust for the different testing protocols for vaccinated and unvaccinated people,” they wrote.

The Lancet told the professors that they were waiting to hear from the paper’s authors before publishing the rebuttal.

No further correspondence was sent until January 2023.

Apology

Josefine Gibson, a senior editor at The Lancet, wrote in a Jan. 8, 2023, email that she saw the submitted rebuttal had not been published.

“We had invited Dr. Sharon Alroy-Preis and co-authors of the published article to consider your letter, but I am sorry that we never received a formal reply from them and therefore have not been able to pursue an exchange,” Gibson wrote. Alroy-Preis is a top Isreali Ministry of Health official.

“But I am even more sorry that I didn’t communicate a decision with you in a timely manner. I will now close your submission, but I thank you for supporting post-publication debate in The Lancet,” Gibson added.

Fenton released the email online, triggering a flood of criticism of the decision not to publish the rebuttal. He and Neil also noted that Alroy-Preis had declared no conflicts of interest, despite Israeli health officials entering into the collaboration that outlined a close partnership.

“The world relied heavily on a major Israeli study in the Lancet which confirmed Pfizer vaccine efficiency, but the lead author failed to declare her conflict of interest in which she signed a contract not to release information detrimental to Pfizer’s product without their permission,” Fenton and Neil wrote in a blog post.

The criticism triggered another message from Gibson, who said The Lancet was “looking into next steps” regarding the rebuttal.

Offer of Publication
After Fenton highlighted what had happened to Richard Horton, The Lancet’s editor-in-chief, Gibson told him that she wanted to apologize “for the substandard experience you’ve had with the Lancet.”

“Having discussed this unfortunate situation with my Editor in Chief, Richard Horton, I would like to offer publication of your original letter. Alternatively, we could publish a new letter that reflects more a current experience with the Pfizer vaccine. We defer to your best judgement of what would best serve the medical community,” she said. “We very much hope you’ll accept this offer.”

Fenton and Neil penned an updated rebuttal, which concluded that the Pfizer–Israel study should be retracted due to reasons including the undeclared conflict from Alroy-Preis and the failure to adjust for different testing protocols. They also raised concerns about adverse reactions to the vaccine, which they said are now known to be “substantial.”

Gibson rejected the updated rebuttal.

“Given existing evidence about the effectiveness and safety of the Pfizer vaccine, it is factually incorrect–indeed, it is misinformation–to say that reported adverse reactions are ‘substantial,'” she wrote.

The Lancet also does not consider Alroy-Preis’s job at the Israeli Ministry of Health to be an undeclared conflict of interest, Gibson said.

New Emails

The situation prompted Fenton to seek internal correspondence regarding him.

The emails were prompted by Fenton’s publication of Gibson’s apology letter.

The tranche was heavily redacted, but did show how officials considered public statements about the vaccine.

“Both Fenton [redacted] have retweed anti-vaxx posts on Twitter, and their Substack articles are worth a scan,” one email stated, referring to Fenton and Neil. “[redacted] experts to determine if Fenton’s original letter and his criticisms of the article are valid and meet our publication standards.”

The email recommended holding off on further correspondence with Fenton until confirming redacted information, “especially given that anything you say directly to Fenton has the potential to be shared.”

In another missive, officials said there had been new developments on “the Fenton Twitter case,” including an additional post by Fenton and “helpful background on Fenton.” The rest of the email was redacted.

That’s when officials said that Fenton had been investigated and found to have “a legitimate academic appointment.” Officials also said that “[redacted] a source of vaccine misinformation is an academic prof based right around the corner from our Lancet offices.”

Officials then proposed what ended up being the final response that rejected the updated submission. They revised the response to change “associated adverse reactions” to “reported adverse reactions.”

Unhappy With Redactions

Fenton said that many of the redactions appeared unnecessary and that he has asked Elsevier to remove them.

“I am not happy about the scale of the redactions in the Elsevier response. If the Lancet editors were not making disparaging comments about me and colleagues, then there should be no reason to redact them. What do they have to hide?” he wrote on Substack.

“The Lancet are hiding their internal correspondence relating to the submission (and ultimate rejection) of our letter criticising Pfizer,” Neil wrote on Twitter. “They are however happy to let us know that they think of us as ‘anti-vaxxers’ and ‘misinformation spreaders’!”

Fenton said he’d informed Elsevier if it did not remove many of the redactions, he would report them to the Information Commissioner’s Office.

Elsevier did not respond to a request for comment.

https://www.theepochtimes.com/health/emails-show-journals-discussion-before-rejecting-paper-challenging-pfizers-claim-of-95-percent-vaccine-effectiveness_5124648.html

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Germany’s Health Minister changes tune on vaccine injuries -- Karl Lauterbach is having a dramatic fall from grace

Outside of Germany, few people have heard of Karl Lauterbach, Germany’s Minister for Health. But he’s one of the key figures in the Western Covid response. Once hailed as a hero, he’s now engulfed in the biggest vaccine-injury scandal to have emerged since the pandemic.

Lauterbach has served in the role since December 2021, under the traffic light coalition led by Olaf Scholz. Often described as “Germany’s Fauci”, Lauterbach — a professor of health economics and epidemiology and long-time member of the SPD — rose to national prominence early on into the pandemic as a Covid hardliner.

In his role as an advisor to Angela Merkel and prominent TV and Twitter commentator, and then as the country’s health minister, Lauterbach adopted an aggressively pro-lockdown and pro-vaccination stance, claiming that his aim was to vaccinate every single German — through the imposition of mandates, if necessary — in order to achieve so-called “herd immunity”.

Like most countries, Germany didn’t make vaccination legally mandatory for the general population, but rather made it de facto mandatory by making one’s Covid status a precondition for leading anything resembling a normal life — and making life impossible for the unvaccinated, including through targeted lockdowns.

A small but vocal minority of politicians — including the far-Left Sahra Wagenknecht and the far-Right AfD — opposed Lauterbach’s mass vaccination policies, warning about the side effects of these novel mRNA-based vaccines. Lauterbach responded by claiming — not only in a now-infamous tweet but also in several talk shows — that the Covid vaccines were “without side effects”. It was an astonishing claim, considering numbers from Germany’s own Ministry of Health showed (also repeated by Lauterbach himself) that reported serious adverse events occurred in one in 5,000 vaccinations. This increased up to 2 in 1,000 for all suspected adverse events.

Those words are now coming back to haunt Lauterbach. Over the past two years, more than 300,000 cases of vaccine side effects have accumulated in the Ministry’s own system, and more and more people are lodging compensation claims against the state — which, based on the contracts signed by the EU with vaccine manufacturers, is liable for any vaccine-related damage. Meanwhile, the subject of vaccine injuries has begun to be openly discussed in the German mainstream media.

All this has forced Lauterbach to make a spectacular U-turn. In a recent TV interview, he admitted that vaccine-induced injuries are a serious issue, and that his ministry was planning to launch a programme to investigate the negative consequences of Covid vaccination and improve care as soon as possible. Additionally, Lauterbach said that he hopes pharmaceutical companies will voluntarily help to compensate those harmed by the vaccines. “That’s because the profits have been exorbitant”, he said. Just a year ago he had said: “The pharmaceutical companies will not get rich with vaccines”.

Lauterbach’s words were welcomed by opposition parties, with the CDU now calling for an inquiry to investigate the government’s Covid response, but drew mixed reactions from his own coalition allies. “Such statements don’t contribute to strengthening Germany as a research and medicine location,” said the pharmaceuticals expert of the FDP coalition party — a reference to BioNTech’s recent decision to boost its investment in the country. This also explains Scholz’s silence.

It’s hard to imagine a more ruinous fall from grace for Lauterbach: in just over a year he’s gone from national hero to symbol of the pandemic failures. On this issue, we may only be beginning to scratch the surface.

https://unherd.com/thepost/germanys-health-minister-changes-tune-on-vaccine-injuries/

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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America’s COVID Response Was Based on Lies

By SCOTT W. ATLAS

Almost all of America’s leaders have gradually pulled back their COVID mandates, requirements, and closures—even in states like California, which had imposed the most stringent and longest-lasting restrictions on the public. At the same time, the media has been gradually acknowledging the ongoing release of studies that totally refute the purported reasons behind those restrictions. This overt reversal is falsely portrayed as “learned” or “new evidence.” Little acknowledgement of error is to be found. We have seen no public apology for promulgating false information, or for the vilification and delegitimization of policy experts and medical scientists like myself who spoke out correctly about data, standard knowledge about viral infections and pandemics, and fundamental biology.

The historical record is critical. We have seen a macabre Orwellian attempt to rewrite history and to blame the failure of widespread lockdowns on the lockdowns’ critics, alongside absurd denials of officials’ own incessant demands for them. In the Trump administration, Dr. Deborah Birx was formally in charge of the medical side of the White House’s coronavirus task force during the pandemic’s first year. In that capacity, she authored all written federal policy recommendations to governors and states and personally advised each state’s public health officials during official visits, often with Vice President Mike Pence, who oversaw the entire task force. Upon the inauguration of President Joe Biden, Dr. Anthony Fauci became chief medical advisor and ran the Biden pandemic response.

We must acknowledge the abject failure of the Birx-Fauci policies. They were enacted, but they failed to stop the dying, failed to stop the infection from spreading, and inflicted massive damage and destruction particularly on lower-income families and on America’s children.

More than 1 million American deaths have been attributed to that virus. Even after draconian measures, including school closures, stoppage of non-COVID medical care, business shutdowns, personal restrictions, and then the continuation of many restrictions and mandates in the presence of a vaccine, there was an undeniable failure—over two presidential administrations—to stop cases from rapidly escalating.

Numerous experts—including John Ioannidis, David Katz, and myself—called for targeted protection, a safer alternative to widespread lockdowns, in national media beginning in March of 2020. That proposal was rejected. History’s biggest public health policy failure came at the hands of those who recommended the lockdowns and those who implemented them, not those who advised otherwise.

The tragic failure of reckless, unprecedented lockdowns that were contrary to established pandemic science, and the added massive harms of those policies on children, the elderly, and lower-income families, are indisputable and well-documented in numerous studies. This was the biggest, the most tragic, and the most unethical breakdown of public health leadership in modern history.

In a democracy, indeed in any ethical and free society, the truth is essential. The American people need to hear the truth—the facts, free from the political distortions, misrepresentations, and censorship. The first step is to clearly state the harsh truth in the starkest possible terms. Lies were told. Those lies harmed the public. Those lies were directly contrary to the evidence, to decades of knowledge on viral pandemics, and to long-established fundamental biology.

Here are the 10 biggest falsehoods—known for years to be false, not recently learned or proven to be so—promoted by America’s public health leaders, elected and unelected officials, and now-discredited academics:

SARS-CoV-2 coronavirus has a far higher fatality rate than the flu by several orders of magnitude.

Everyone is at significant risk to die from this virus.

No one has any immunological protection, because this virus is completely new.

Asymptomatic people are major drivers of the spread.

Locking down—closing schools and businesses, confining people to their homes, stopping non-COVID medical care, and eliminating travel—will stop or eliminate the virus.

Masks will protect everyone and stop the spread.

The virus is known to be naturally occurring, and claiming it originated in a lab is a conspiracy theory.

Teachers are at especially high risk.

COVID vaccines stop the spread of the infection.

Immune protection only comes from a vaccine.

None of us are so naïve as to expect a direct apology from critics at my employer, Stanford University, or in government, academic public health, and the media. But to ensure that this never happens again, government leaders, power-driven officials, and influential academics and advisors often harboring conflicts of interest must be held accountable. Personally, I remain highly skeptical that any government investigation or commission can avoid politicization.

Regardless of their intention, all such government-run inquiries will at least be perceived as politically motivated and their conclusions will be rejected outright by many. Those investigations must proceed, though, if only to seek the truth, to teach our children that truth matters, and to remember G.K. Chesterton’s critical lesson that “Right is right, even if nobody does it. Wrong is wrong, even if everybody is wrong about it.”

https://www.independent.org/news/article.asp?id=14446&omhide=true&trk=title

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Covid’s cockups and conspiracies: Australia wasn’t immune

Those debating whether the deadly schemozzle of pandemic mismanagement that has cast a pall over the last three years was due to a cockup or a conspiracy should abandon binary thinking. All the evidence, from both sides of the Atlantic, indicates that there were both cockups and conspiracies and they came not as single spies but in battalions.

In the UK, the ‘Lockdown files’, a trove of 100,000 WhatsApp messages released by the Telegraph over the last week, provide a portrait of former health minister Matt Hancock as a cruel careerist and a clown better suited to appearing on ‘I’m a Celebrity… Get Me Out of Here’, which he did for a fee of hundreds of thousands of pound, rather than running Britain’s pandemic policy.

The liberty of millions of Britons was curtailed based on the whims of decision-makers who, because they were not subject to parliamentary scrutiny, simply claimed they were following the best scientific advice.

Guilt and fear were shamelessly used to enforce the draconian dictates with Hancock writing that he would ‘frighten the pants off everyone’ with a new strain to get compliance.

A fan of Klaus Schwab and the World Economic Forum (WEF), Hancock wrote that he hoped Covid would propel his career into the next league. He discussed with his advisers how ‘pushing on vaccines’ would be ‘the most politically beneficial thing’ to do. When Dame Kate Bingham who led the UK vaccine taskforce suggested in October 2020 that only people who were ‘at risk’ should be vaccinated, Hancock branded her as ‘wacky’ and ‘totally unreliable’.

In the US, the Twitter files made public by Elon Musk exposed a conspiracy between key members of Team Biden, agencies such as the FBI and Big Tech to help Biden get elected and to censor and smear those who criticised the government orthodoxy.

Evidence of conspiracies continues to be uncovered by House Republicans. The latest emails show that Dr Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases from 1984 to 2022 and chief medical advisor to the president from 2021 to 2022 and Dr Jeremy Farrar, director of the Wellcome Trust, the third largest charitable foundation in the world, hid their roles in February 2020 in the writing of a scientific paper whose purpose was to cast as much doubt as possible on the fact that the Covid virus originated in a lab in Wuhan. Both pretended they played no part in the paper’s genesis but both prompted the scientists to write it, Farrar edited it and Fauci hid the fact that his agency funded research in a Wuhan lab to make bat coronaviruses more dangerous.

In view of Farrar’s role in obfuscating the origins of Covid, leading scientists such as Dr Richard Ebright, a microbiologist at Rutgers University, has called for him not to take up an appointment announced last year to be the next chief scientist at the World Health Organisation.

Farrar also signed a notorious letter to the Lancet organised by Peter Daszak, the CEO of the EcoHealth Alliance who provided US tax dollars for research into bat coronaviruses at the Wuhan Institute of Virology. The letter condemned as ‘conspiracy theories’ any suggestion that Covid-19 did not have a natural origin.

Conspiracies were not limited to promoting lies about the origins of Covid. As Dr Marty Makary, a professor of surgery and health policy at Johns Hopkins University said in sworn testimony before the House Select Subcommittee on the Coronavirus Pandemic’s first hearing on Tuesday 28 February, ‘The greatest perpetrator of misinformation during the pandemic has been the United States government’.

Makary damned public health officials for lying to the American people that Covid was spread through surface transmission, that vaccinated immunity was greater than natural immunity, that masks were effective, that myocarditis was more common after infection than vaccination, that young people benefit from a booster and that vaccine mandates would increase vaccination rates. ‘We’ve seen something that is unforgivable,’ he said, ‘and that is the weaponisation of medical research itself’.

The common link between the UK cockups and the US conspiracies is the total disregard for scientific evidence, which either didn’t exist or contradicted what policy makers wanted to do and so was ignored or discredited.

There is no comfort for Australia in any of this. Like Little Sir Echo it copied all of its pandemic policies from the US and the UK. The question is what to do now?

It is impossible to prevent cockups or conspiracies, but it is possible to make them more difficult to engage in by subjecting governments and their agencies to greater scrutiny. We could start by requiring that they table all health advice.

Agencies such as the Therapeutic Goods Administration (TGA) need to collect more data about adverse events, for example, by requiring the same information that is collected in the US. It needs to publicly state the background rates for adverse events, the rate of these events for comparable drugs, and provide a weekly update on the rate of these events in new products so that dangerous drugs can be withdrawn as soon as warning signs appear.

The meetings of committees that advise the TGA should be publicly televised as they are in the US and anybody who advises the TGA or any other part of government on health should be required to publicly disclose any funding they receive from pharmaceutical companies or other interested parties.

The power of the Australian Health Practitioner Regulation Agency needs to be curbed. By issuing an edict telling healthcare workers that they must do nothing to undermine confidence in the government’s response to the pandemic, it pressured health practitioners not to report adverse events or tell their patients about the potential for adverse events.

The misinformation and disinformation laws tabled by the Morrison and now by the Albanese government are also a shameless attempt to curtail totally justified criticism of pandemic polices.

Too often over the last three years, Australians’ rights and freedoms have been violated in the interest of ‘public health measures’ that were harmful.

Only by making the work of the government and its agencies fully transparent can we start to restore confidence that we will be subjected to anymore conspiracies or cockups.

https://www.spectator.com.au/2023/03/covids-cockups-and-conspiracies/

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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Covid: The vaccinations did more harm than the disease

Robert Clancy

As a clinical immunologist with a research interest in mucosal immunology and airway infection, the Covid-19 pandemic became a point of convergence for my interests in medicine, research and history.

An Australian response to pandemics over 70 years was a critical influence in public health and applied research reflecting informed leadership.

The Covid-19 pandemic has not followed that course.

Suddenly everyone was an ‘epidemiologist’, dominating the airwaves and working with political and regulatory organisations to protect the global narrative, reinforced and uncritically accepted by the mainline press, to ‘combat spread of harmful vaccine disinformation’.

Three years ago, there was every reason to fear Covid-19. High mortality and transmission rates were reported in China, and the world experience with pandemics was sobering. No effective drug or vaccine existed, with management focussed on public health measures. Genetic vaccines were available from January 2021, with Australia becoming one of the most vaccinated countries. Total Covid-19 deaths per million paralleled global mortality, though later in the pandemic from the less virulent Omicron variant. This surge followed relaxation of lockdowns, and the vaccine booster programme

Returning to 2020, it was natural to think that vaccines may play a role in managing Covid-19. In various forms, vaccines were used in earlier pandemics without playing a decisive role. There were important lessons that should have informed a less sanguine approach to the narrative of mRNA vaccines being the global panacea for Covid-19. This information was available before 2021!

The apologists backtracking on mistakes in the vaccine roll-out, with ‘we just did not know’, have no argument.

First, 80 years of vaccine development for inhaled viral infections, failed to develop one sterilising vaccine capable of inducing herd immunity. Second, no vaccine induces stronger immunity than that following the disease, yet it took a recent Lancet meta-analysis to confirm that post Covid-19 trumps vaccine immunity. Third, respiratory viruses like Sars-CoV-2 infect a mucosal space subject to the rules of mucosal immunology. The major difference from the systemic immune response to invasive pathogens is suppression of all immune responses by T reg cells (to control the inflammatory response to the sea of microbes bathing mucosal surfaces). With Covid-19, immunity following injected vaccines is limited; repeated ‘boosters’ favour progressive immune suppression with more frequent and more severe infections. ‘Allergy-shots’ do the same – they turn off damaging immune responses to inhaled antigens. There is little cross-over between compartments: injected vaccines will not prevent infection, or transmission of disease (a claim used to support community vaccination). Fourth, RNA viruses undergo mutations facilitating ‘immune escape’, risking ‘selection’ of mutant virus by non-sterilising vaccines.

These ‘rules’ predict outcomes of the Covid-19 vaccine roll-out. Vaccination induced systemic immunity probably prevented admission to hospital and death by neutralising virus that ‘escaped’ from the mucosal compartment, but only early in the pandemic when vaccine antigen matched prevailing virus and before priming of suppression from repeated vaccinations. There was no impact on infection or transmission of the virus. Repeated ‘boosters’ gave 30 to 40 per cent protection for a couple of months, followed by cumulating ‘negative protection’ with more severe and frequent infections. New Zealand figures indicate higher Covid-19 mortality in every age bracket, in those with ‘boosters’, reflecting a global pattern described by some as a ‘pandemic of the vaccinated’.

The mRNA vaccines differ from classical antigen vaccines. They spread and persist for months, producing Spike protein (the viral antigen stimulating immune protection) on cells throughout the body. The consequences are an uncontrolled amount of antigen that can downregulate antibody, and a new target for T cells to attack. Reports of serious adverse events following Covid-19 vaccination including heart and brain damage and deaths outstrips combined reports for all other vaccines. Prospective study of adolescents using laboratory and MRI technology showed 2 to 3 per cent had myocarditis, contrasting with less sensitive hospital figures of one in 10,000 vaccinations. Asymptomatic myocarditis leaves a scar, claimed to underpin a recent spate of adrenaline-initiated deaths on sporting fields. German post-mortem studies confirm vaccine pathology as a significant cause of sudden unexplained deaths. Statisticians across the world are seeing an increase in deaths of the order of 10 to 20 per cent greater than noted in previous years, time-matched with vaccine rollouts. These data demand proper assessment despite dismissal by authorities. Reversal of mRNA encoded information into host DNA has been documented, with unknown impact on the recipient or their progeny.

The point is this. How could a novel vaccine involving mRNA with scarce testing, with no demonstrated advantage over traditional vaccines, against all principles of mucosal immunology, and likely complicated by major adverse events, not be red-flagged by the medical-regulatory network charged with our protection? Peter Doshi, an editor of the prestigious BMJ, co-authored a review of the trial data used to underpin vaccine mandates. The authors concluded, ‘the risk of serious adverse events surpassed the risk reduction for Covid-19 hospitalisation’, demanding a ‘formal harm-benefit analysis’. This never occurred. How can it be?

We live in strange times, when the globalisation of a narrative formulated and promoted by powerful interests linked to the lure of massive profit and control, threatens 500 years of the enlightenment and science. In Australia, acceptance of the Covid-narrative was made easy by the unrecognised power of these interests and a disintegration of core medical structures that once would have demanded science-based analysis, regulatory integrity and effective review. The introduction of unique, clever technology blindsided mainstream professionals who failed to understand the implications of genetic vaccines, or the immunology of the airway. These ‘experts’ and bureaucrats made poor decisions which became rubber-stamped by administrators and politicians. ‘Cancellation’ threats to those scientists and clinicians wishing to speak out against the narrative, enabled disinformation to become convention, with frightening unknown consequences.

https://www.spectator.com.au/2023/03/strange-times/ ?

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Australian research findings could fast-track treatment for long Covid patients

New research from Griffith University has revealed that long Covid and chronic fatigue syndrome can have similar effects on brain structure – offering hope to finding a treatment to long Covid.

Using an ultra-high field MRI, Griffith researchers investigated how the two conditions mirror the same effects on the brain in both myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long Covid patients, with the results showing major consistencies in brain-stem volume in these patients compared to those who did not suffer from the same ailments.

The research came after reports that 13-58 per cent of long Covid patients experienced symptoms similar to chronic fatigue syndrome, including brain fog, fatigue, pain, and autonomic dysfunction.

Lead author Dr Kiran Thapaliya said the MRI results revealed larger brain stems in long Covid and ME/CFS patients compared to those without the conditions. “It also showed similar volumes of the brain stem in patients which could be the reason long Covid patients exhibit all common core symptoms of ME/CFS,” Dr Thapaliya said.

“We also discovered smaller midbrain volumes were associated with more severe breathing difficulty in ME/CFS and long Covid patients. “Therefore, brain-stem dysfunction in ME/CFS and long Covid patients could contribute to their neurological, cardiorespiratory symptoms, and movement disorder.”

Dr Thapaliya said these findings could lead to further research into treatment and management of long Covid, which had previously been poorly understood and difficult to diagnose.

“Since we saw that there was an overlap between MECFS and long Covid, this could fast-track the treatment for the long Covid patients,” Dr Thapaliya said.

“For the treatment of chronic fatigue syndrome, we have used low dose Naltrexone, so this might pass as a treatment for long Covid persons So this could potentially fast-track finding a treatment”.

According to health experts, up to 43 per cent of people infected by SARS-CoV-2 did not recover fully and develop long Covid, including children.

Researchers at Griffith University will continue investigating the correlation between these two illnesses, including testing on a larger sample size and looking at the duration of the brain stem changes

“The next stage of our research is to see whether these changes in the brain stem are temporary, or permanent in long Covid and CFS patients,” Dr Thapaliya said

https://www.couriermail.com.au/news/queensland/griffith-university-research-could-fasttrack-treatment-for-long-covid-patients/news-story/32470e206a8f459aba6c44bde0679d96

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UK: The Hancock texts

If readers don’t know, Hancock was the Health Minister in Britain through virtually the entirety of Covid. A while back he approached the UK journalist Isabel Oakeshott to ghost-write his memoirs or book on the Covid years. To do this Hancock gave her all of his encrypted WhatsApp texts to everyone that mattered during the entire pandemic years.

Oakeshott wrote the book and then, even though she’d promised not to, she gave the entirety of these WhatsApp texts to the UK Telegraph. My take is that the Telegraph is covering itself in glory publishing these texts. And the various journalists criticising Oakeshott for ‘betraying’ Hancock (and for doing her job, really) are the very same ones who didn’t do theirs. For two-plus years.

Sure, it’s generally a good rule not to break promises. That has social utility. But it’s not an absolute good nor the only important value in life. There are lots of others. And releasing these texts massively outweighed the promise-keeping virtue here. As Oakeshott said, otherwise there was going to be a whitewash. It was in the public interest for people to see these texts and know that their political class was comprised of charlatans and heartless zealots fired by self-interest, making things up on the fly and continually mouthing ‘this is the Science’ when they knew it simply was guesses, seat-of-pants guesses at that, and cover to look good politically.

You have to read some of these released text messages to believe them. Children made to mask-up when they knew there was no scientific evidence, none, for doing so but the politics were good. Top bureaucrats laughing at people who would have to go from business class flights into pokey little hotel rooms for weeks on end. The explicit targeting of sceptics and dissenters, including some of the best epidemiologists in the world, to discredit them and have them silenced because that was undercutting the pollies’ messaging – no mention of truth, notice. When they were told various idiotic rules had no utility they carried on with them because to do otherwise might make them look bad. Seriously, go and read these WhatsApp revelations because we citizens can never again trust these (what’s the word I’m looking for? Two syllables. Might start with an ‘f’).

It will be extra tough reading for those whose small businesses were destroyed. Or those with children whose lives were ruined. (And yes we knew from day one that the chances of a healthy person under 30 dying from Covid was less than one one-thousandth that of someone over 75. It was essentially zero. They knew it too.) Or those who resisted useless mandates. Well, it’ll be cold comfort reading these texts but do it. Because all of us labelled ‘conspiracy theorists’ were right on almost everything. And the whole ‘fact-checking’ industry is nothing more than partisan opinion claims, often worse and verging on a propaganda operation, on behalf of out-of-control government. Laugh at the mere mention of ‘fact checkers’ – the same goes, by the way, for the supposed fact-checkers around the Voice and its implications.

Project Fear succeeded because we citizens let it. Never again can it happen. We should shame every MP who played this game and perpetuated this disgusting thuggery and illiberal anti-science that have destroyed people (both those against the lockdowns and equally those in favour, some of whom have literally lost all ability to weigh data and make sane choices as a result).

Again, Australia right now has sky-high excess deaths. If the goal of lockdowns was to save more lives than it cost then it has failed miserably on its own terms. The incredible stupidity of Hancock in being so arrogant that it never occurred to him not to give away otherwise encrypted texts (which made the writers more forthcoming than otherwise) has done us all a huge favour. And every single Australian knows in his or her heart that our own politicians were no different than Britain’s – no less self-serving, focused on PR and fearmongering, clueless on the data, afraid to stand up to the worst elements of the modelling class, etc. Read ‘em and weep readers.

https://www.spectator.com.au/2023/03/whatsappalling/

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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1 Shot of interferon lambda Might Boost Immunity and Fight COVID Across Variants. Review of a potential novel treatment for COVID-19

Yet another COVID-19 treatment has emerged, but is interferon lambda the miracle cure the world has been waiting for?

Summary of Key Points

* Currently available COVID-19 treatments have limitations and concerns.

* A new clinical trial shows promise for interferon lambda, effective against all variants and drops viral loads faster than other COVID-19 treatments.

* Interferon lambda is a “one-and-done” treatment.

* Interferon lambda has little interaction with other drugs, making it a safer treatment option for many individuals.

* The Food and Drug Administration has not approved interferon lambda as a COVID-19 treatment; emergency use authorization is still pending.

Limitations and Concerns With Current COVID-19 Treatments

The currently available treatments for COVID-19 have been far from perfect, with each presenting its limitations and concerns.

For instance, questions have been raised about the safety and effectiveness of Molnupiravir, while Paxlovid is associated with a high number of cross-drug interactions, and there are concerns about managing rebound syndrome.

On the other hand, three days of intravenous remdesivir is cumbersome to set up, requiring a visit to an infusion center or dedicated home care service. More importantly, the drug has caused potentially fatal side effects, including kidney failure.

Additionally, Omicron and its subsequent mutations have made all previously available monoclonals ineffective.

In this context, a recent clinical trial has shown promising results for pegylated interferon lambda, a naturally occurring protein produced by the immune system in response to viral infections. The study showed interferon lambda could reduce COVID-19 risk by up to 50 percent.

What Is Interferon Lambda?

Interferons (IFNs) are a group of proteins produced by the immune system in response to viral infections. These proteins have antiviral, anti-tumor, and immunomodulatory effects and regulate the immune system. There are three types of interferons: type I, type II, and type III.

All types of IFNs have similar effects on the body but activate different sets of genes.

Interferons work by “interfering” with viral replication and infection. This is done by activating pro-inflammatory pathways, recruiting immune cells, or targeting viral replication by breaking down its proteins, enzymes, and RNA.

Type I and type II interferons launch a systemic antiviral response throughout the body. On the other hand, type III interferons are limited to epithelial cells and specific immune cells like neutrophils.

This indicates that type III interferons provide targeted protection for skin, gut, and lung surfaces while minimizing the side effects.

Given the characteristics of interferons, especially considering the specificity of type III interferons, they are useful for treating acute and chronic viral infections.

Previously, type I IFNs have been used to treat chronic hepatitis C and B viral infections. Although effective, they have significant side effects, such as flu-like symptoms, nausea, and fatigue, as they can theoretically affect almost all cells in the body. In contrast, studies (1,2) in mice showed that type III interferon (IFN-λ) was more effective at preventing and treating influenza viral infections with fewer side effects. Additionally, in treating hepatitis C, interferon lambda was equally as effective as type I IFNs, with milder side effects.

Regarding the timing of infection and host defense, IFNλs are the first IFNs that defend at the epithelial barrier to inhibit the initial spread of viruses without triggering inflammation.

In the context of COVID-19, type III interferons are more appropriate for development as a treatment for three reasons.

Firstly, interferon lambda works on the same locations, namely the respiratory and gastrointestinal systems where COVID-19 primarily attacks, so as to result in greater inhibition of viral replication from the nasal epithelium to the upper respiratory tract.

Secondly, most severe COVID-19 patients experience cytokine storms. Avoiding systemic inflammation is essential to reduce the risk of a cytokine storm and prevent the exacerbation of COVID-19 symptoms.

Lastly, type III interferons are localized to epithelial cells and confer long-lasting antiviral effects in the upper respiratory tract and block virus transmission, according to a report from a German laboratory study.

Interferon Lambda Works Differently Than Other COVID-19 Treatments

While most COVID-19 treatments are exogenous, meaning they are produced outside the body and later introduced to the body, interferon lambda is endogenous, produced naturally by the body in response to viral infections.

This means that interferon lambda, even if administered exogenously, is less likely to cause adverse effects, and is less likely to interact with other medications.

Interferon lambda works with your natural immune system, not against it. This differs from other COVID-19 treatments, such as vaccines, that aim to “hack” your immune system into working for you. The beauty of interferons is that your immune system can immediately use them. The idea is that we are letting our immune system do the work with a little boost from outside.

Interferon lambda triumphs above other COVID-19 treatments due to the following:

* Effective against all virus variants, including the Delta and Omicron variants.

* Drops viral loads faster than other treatments, making it an effective way to limit the spread of the virus.

* Interferon lambda is a “one-and-done” treatment.

* Little interaction with other drugs makes it a safer treatment option for many individuals.

Interferon Lambda Clinical Trial Shows Promise for COVID-19 Treatment

Two studies (1, 2) have reported the results of phase 2 clinical trials on the impact of pegylated interferon lambda on the viral load of SARS-CoV-2. Phase 2 clinical trials are small studies designed to test the safety and effectiveness of new drugs, whereas phase 3 clinical trials involve hundreds to thousands of participants.

The breakthrough study published in the New England Journal of Medicine (NEJM), “Early Treatment With Pegylated Interferon Lambda for COVID-19,” was the phase 3 trial many people were waiting for, and the results are intriguing.

The phase 3 clinical trial recruited 2,617 participants, of whom 933 were randomly assigned the treatment of pegylated interferon lambda, while 1,018 received a placebo. The remaining 666 patients were assigned to other intervention groups.

The placebo group was given either a single subcutaneous injection or an oral placebo. The median age of all the patients was 43 years, ranging from 18 to 92.

Of the patients in the interferon group, 25 of 931 (2.7 percent) showed a primary-outcome event, meaning the patient suffered from hospitalization or emergency treatment, compared to 57 of the 1,018 (5.6 percent) placebo patients. The difference shows a reduction of 51 percent risk between the control and placebo.

Additionally, there were no differences in the incidence of adverse events between the control and placebo groups, showing that the interferon lambda therapy did not lead to, at least in the scope of this study, more side effects.

Overall, patients who received a single dose of pegylated interferon lambda were significantly less likely to require hospitalization or an emergency department visit due to COVID-19 than those who received a placebo.

Our Genes Decide the Response to Interferon
It’s important to note that there are limitations to using interferon lambda injections. First, the COVID-19 patients were treated early—within 7 days after the onset of symptoms as defined in the NEJM clinical trial.

Secondly, only non-hospitalized patients were included in the study. Patients requiring hospitalization or who exhibited signs of severe COVID-19 symptoms were excluded from the trial.

Thirdly, not everyone responds to interferon therapy. Some intrinsic factors predetermine our response to interferons, such as our genes.

For example, a 2022 study published in Nature examined the OAS1 gene, which is activated by interferons to produce an important enzyme that helps the body fight viral infections.

The study discovered that a common gene pattern of OAS1, called a haplotype, was linked to an increased risk of severe illness and reduced clearance of the COVID-19 virus.

Evaluation of the prevalence of this haplotype is warranted, yet the interplay between COVID-19 and specific genes raises a bigger question regarding the impact of our genes on disease.

Let’s take approaches to happiness as an example. Hedonic lifestyles prioritize pleasure and positive emotions, such as joy, excitement, and satisfaction, and may involve activities such as indulging in good food, entertainment, or material possessions.

In contrast, eudaimonic lifestyles prioritize meaning, purpose, and personal growth and may involve pursuing challenging goals, contributing to the greater good, and cultivating meaningful relationships. While both approaches can bring about positive feelings and experiences, eudaimonic well-being tends to be more sustainable and satisfying over the long term, as it is rooted in the sense of purpose and deeper fulfillment beyond the pursuit of immediate pleasure.

In a study published in PNAS, researchers found that individuals who lived a eudaimonic lifestyle had higher interferon gene expression and significantly lower expression of pro-inflammatory genes.

On the other hand, individuals living a hedonistic lifestyle showed higher expression of pro-inflammatory genes and downregulation of interferon gene expression.

The study suggests that the interconnectedness between mind and body is powerful and should be taken into account when trying to prevent or treat illness.

https://www.theepochtimes.com/health/1-shot-might-boost-immunity-and-fight-covid-across-variants_5100290.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH) Also here

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH) Also here

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

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