Coronavirus: why aren’t we talking more about vitamin D?

BAME people suffer more from Covid-19, but the problem probably isn't racism.

One area of anger in recent protests against racism has been the differential impact of Covid-19 on black, Asian and minority-ethnic (BAME) people. But assuming that viruses don’t discriminate, can those deaths really be put down to racism or is there something else going on?

One idea is that there may be something simpler going: vitamin D deficiency. Normally, when people talk about vitamin or mineral deficiencies, I tend to switch off. There is a mildly hypochondriac tendency in modern society to think that we should all be obsessing about supplements of all sorts of trace elements and odd herbal remedies. I tend to give Holland & Barrett a wide berth.

But the case for vitamin D seems stronger. Usually simply thought of as being a factor in osteoporosis and other bone conditions, vitamin D actually has a much wider impact in our bodies than that. In particular, it seems to play a role in regulating aspects of our immune system.

As the science writer Matt Ridley noted in May: ‘There has long been evidence that a sufficiency of vitamin D protects against viruses, especially respiratory ones, including the common cold. Vitamin D increases the production of antiviral proteins and decreases cytokines, the immune molecules that can cause a “storm” of dangerous inflammation. It has long been suspected that most people’s low vitamin D levels in late winter partly explain the seasonal peaking of flu epidemics, and rising vitamin D levels in spring partly explain their sudden ending.’

All sorts of effects of vitamin D have been suggested in recent years. For example, it seems to help with autoimmune diseases, where our immune systems become harmful to us. Type 1 diabetes, multiple sclerosis and psoriasis have been characterised in this way. Type 2 diabetes, usually thought of as a metabolic disease, may in part be an autoimmune disease, too. (Notably, BAME people have much higher rates of type 2 diabetes than white people.)

What does all this have to do with the colour of our skin?

Vitamin D is, arguably, not a vitamin at all, which is usually defined as something we need to get from our diet. The majority of our vitamin D comes from the effect of sunlight – ultraviolet light specifically – on our skin, where a derivative of cholesterol is converted into vitamin D. In northerly latitudes like the UK, we don’t get enough sunlight to produce vitamin D for six months of the year. This is even more pronounced for people with darker skin – it takes more sun exposure to produce sufficient vitamin D than it would for pale-skinned people.

A survey of evidence by Karl Pfleger shows several different lines of evidence pointing to vitamin D as an important factor in Covid-19. For example, comparing the vitamin D status of Covid-19 hospital patients has shown that the ones with low vitamin D are much more likely to end up in intensive care. Areas in northerly latitudes are more likely to be hard hit, but this is offset in countries where supplementation – through fortifying foods – is more common.

Perhaps another pointer is the fact that the first drug to show real promise in treating patients is dexamethasone – a steroid. Steroids work by decreasing inflammation and reducing the activity of the immune system. Vitamin D is a steroid, too. (To be more precise, vitamin D is a collective name for a group of steroids.)

So there is plenty of circumstantial evidence that vitamin D deficiency is important in Covid-19 and there are plausible biological mechanisms for why that might be the case. Giving vitamin D to patients who already have plenty seems to have little effect.

Yet a review of evidence by the National Institute for Health and Care Excellence (NICE), published on Tuesday, advised: ‘There is no evidence to support taking vitamin D supplements to specifically prevent or treat Covid‑19. However, all people should continue to follow UK government advice on daily vitamin D supplementation to maintain bone and muscle health during the Covid‑19 pandemic.’

This is a rather odd conclusion. The review examined five peer-reviewed papers. (It ignored the mass of pre-print research that has not had time to go through peer review in the short time the pandemic has been going.) ‘Four of the studies found an association or correlation between a lower vitamin D status and subsequent development of Covid‑19. However, confounders such as body mass index (BMI) or underlying health conditions, which may have independent correlations with vitamin D status or Covid‑19, were not adjusted for.’

The fifth paper, by Hastie et al, found the effect disappeared when these potential confounders were taken into account. NICE seems to lean very heavily on this one paper. But there are two problems. First, vitamin D status was gleaned from UK Biobank data – which was collected at least 10 years ago. Patients’ vitamin D status wasn’t measured at the time they got ill. Second, ethnicity and body mass index (BMI) are not independent variables from vitamin D. Rather, vitamin D deficiency is an attempt to explain why ethnicity and BMI matter. (People with high BMI are also more likely to have low vitamin D.)

Moreover, the cut-off date for the NICE paper meant it didn’t have a chance to consider two pre-prints of particular interest. A study from Singapore found ‘the active form of vitamin D, calcitriol, exhibits significant potent activity against SARS-CoV-2’ (the virus that causes Covid-19). A study on patients in Newcastle in the UK found that ‘patients requiring ITU admission were more frequently vitamin D deficient than those managed on medical wards, despite being significantly younger’.

In short, there is plenty of evidence to point to vitamin D deficiency as a risk factor for Covid-19. Yet officials and politicians seem wary of talking about it. If we were talking about a drug with significant side effects, like hydroxychloroquine (Donald Trump’s Covid drug of choice), we might have cause to be nervous about recommending it. But this is a vitamin and it is well known that many people across the world are deficient.

Indeed, the NHS already suggests that pretty much everyone takes vitamin D supplements, at least over the winter. In Scotland, for example, the NHS Scotland website is clear: ‘Everyone (including children) should consider taking a daily supplement containing 10 micrograms of vitamin D.’ That’s probably far too little. There is little or no risk of overdosing for adults up to 100 micrograms per day, so taking significantly more would address insufficiency more effectively.

The advice is particularly emphasised for certain groups, including: ‘People who have low or no exposure to the sun, for example those who cover their skin for cultural reasons, are housebound, confined indoors for long periods or live in an institution such as a care home; and people from minority-ethnic groups with dark skin, such as those of African, African-Caribbean and South Asian origin, who require more sun exposure to make as much vitamin D.’

There is, of course, the possibility that Covid-19 deaths could be due to poverty, deprivation and ‘systemic racism’. And any research around the disease is obviously new and should be treated as provisional. Vitamin D is unlikely to be a panacea.

But serious cases seem disproportionately related to vitamin D deficiency. Among doctors – who are unlikely to be economically deprived – 94 per cent of deaths have been BAME medics. Moreover, testing for vitamin D deficiency is cheap. Supplements are cheap, widely available and safe. So wouldn’t it be better to focus more of our attention – both medical and research – on the ‘sunshine vitamin’?

SOURCE 

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Appease the Mob, Destroy the Nation

Perhaps the most distressing aspect of the current effort to “fundamentally transform the United States of America” into the Republic of Wokeistan is the seemingly invincible ignorance of history that attends it. The American Left is seeking to impose a totalitarian, Communist Chinese Red Guard worldview on this nation, whereby those who are insufficiently attuned to progressive ideology will be relegated to the margins — at best — and completely destroyed at worst.

Moreover, the smug self-assurance among elitists in media, academia, politics, Hollywood, sports, and business that a sufficient amount of ideological alignment and/or a craven level of guilt-signaling obsequiousness will render them immune from the depredations of the mob is, quite simply, a pipe dream.

As history reveals, the Red Guard movement collapsed from within, when even the most dedicated followers of Maoism were unable to keep up with the ever-increasing demands for absolute purity of thought. And despite leading the French Revolution’s Reign of Terror, during which more than 17,000 “enemies of the people” were guillotined, Maximilien Robespierre was also executed by the same mob he himself created.

Thus, when a number of progressive politicians in Democrat-controlled cities who imposed draconian lockdowns let “protesters” flout social-distancing edicts, while telling cops to stand down; when political hacks like Minneapolis Mayor Jacob Frey grovel before black protesters about “coming to grips with my own brokenness”; or when white police officers wash the feet of BLM protesters while apologizing for the “sins” of the white race, the results of such fecklessness are eminently predictable: Cities are looted and burned, a humiliated Frey is sent packing by an angry mob, and calls to defund police departments reach crescendo pitch throughout the nation.

The mob expects nothing less. In fact, it demands much more, and rigid conformity goes right to the top of the list. New Orleans Saints quarterback Drew Brees, who runs a charity helping sick and needy kids, has learned that no amount of apologizing by him and his wife for daring to suggest the American flag and national anthem are worthy of respect is sufficient. Even worse, he has managed to alienate almost everyone, first for expressing his opinion and then for being guilted into submission by members of a league run by NFL Commissioner Roger Goodell, who has also decided that alienating half of his potential audience is a reasonable tradeoff for being “down with the cause.”

He is far from alone. Amazon mogul Jeff Bezos is “happy to lose” customers who take offense at his decision to virtue signal his support for Black Lives Matter at the top of his website. A&E and Paramount are more than willing to postpone or cancel new episodes of police shows on their respective TV schedules, and HBO Max has temporarily removed 1939’s “Gone With the Wind” until it can attach statements to it denouncing its “racist” content. The New York Times and Philadelphia Inquirer are content to bow to the progressive mob — both outside and inside the newsroom — and allow it to determine what headlines and editorial content is acceptable. Kentucky’s Democrat Governor Andy Beshear has no problem announcing he intends to provide healthcare coverage for “100% of our individuals in our black and African-American communities.”

That such puerile pandering reveals the hypocrisy of a multibillionaire elitist who recently rescinded a two-dollar-an-hour, coronavirus-engendered pay increase for Amazon warehouse workers, even as his net worth increased $32 billion since January? That entertainment networks are attempting to solidify the mindset that there is something inherently wrong with police work and Oscar-winning film classics? That both newspapers have reduced their credibility to zero? That there are Kentuckians of other ethnicities who doubtlessly need healthcare coverage?

That the mob itself is wholly unconcerned with the most lethal, enduring, and primary source of black murders, epitomized by Chicago’s most violent day in 60 years?

An utterly bankrupt ideology must be served.

Let’s be clear: George Floyd and the legitimate protests surrounding his death have been completely co-opted by rank, America-hating opportunists whose motives are crystal clear as soon as reasonable Americans ask themselves a simple question: Who supported the killing of George Floyd? No one in their right minds on any part of the political spectrum, that’s who. Even an overwhelming majority of police have decried the actions of the four individuals involved, all of whom have been arrested and charged.

Thus another telling question inevitably arises: Who, exactly, is the “enemy” that must be vanquished so that “justice” can prevail?

The answer is as simple as it is damning: Anyone and everyone who fails to unquestioningly embrace each and every demand of a nihilist progressive mob. A mob every bit as virulent as any other mob that has sought absolute power throughout the history of mankind. A mob wholly disinterested in compromise, good will, or reconciliation. A mob decades in the making, courtesy of America-contemptuous, progressive indoctrinators presenting themselves as educators, entertainment industry titans who cater to the lowest common denominator, duplicitous multinational CEOs with no allegiance to this nation, progressive prosecutors who disdain the Rule of Law, craven politicians in both parties whose self-interest completely transcends statesmanship, and the useful-idiot talkingheads in the media who shill for all of it, 24/7/365.

“Americans want to stand with those peacefully protesting injustice,” writes columnist Joshua Lawson. “But the radical Left offers either the choice of self-condemnation for evils Americans had no hand in, or to be silent and stay that way. If the second option is chosen, that very silence is viewed as an indictment of ‘complicity’ often seen by the Left as akin to violence itself.”

Thankfully, there are those who refuse to be intimidated. “I took off today, this weekend, but I’m out here just to make sure y'all are safe. Don’t go there with respect, okay? I have much respect, but I only kneel for one person, and that’s God,” stated black Georgia State Trooper O'Neal Saddler.

Next November, the American electorate will face a choice between the mob and people like Mr. Saddler. If Americans embrace the collective guilt demanded by the mob, they will deeply regret it when those same demands for ideological purity that destroyed the Red Guard are imposed on them — and their children — with unrelenting ferocity.

As for the cadre of elitists who mistakenly believe they have bought themselves absolution, columnist Kurt Schlichter gets it exactly right: “Mansions and BMWs burn just like churches and police cars do.”

Indeed they do, Mssrs. Frey, Goodell, Bezos, Beshear, et al. Indeed they do.

SOURCE 

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For more blog postings from me, see  TONGUE-TIED, EDUCATION WATCH INTERNATIONAL, GREENIE WATCH,  POLITICAL CORRECTNESS WATCH, AUSTRALIAN POLITICS, and Paralipomena (Occasionally updated), A Coral reef compendium and an IQ compendium. (Both updated as news items come in).  GUN WATCH is now mainly put together by Dean Weingarten. I also put up occasional updates on my Personal blog and each day I gather together my most substantial current writings on THE PSYCHOLOGIST.

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