Thursday, April 28, 2022

Officials approve a Covid drug that does not work

“I am glad for Gilead as well.”

That was Dr. Clifford Lane, a deputy to National Institute of Allergy and Infectious Diseases (NIAID) boss Dr. Anthony Fauci, in an April 29, 2020 response to Tomas Cihlar, a senior vice president at the pharmaceutical company Gilead, developer of the drug remdesivir.

As the Epoch Times reports, recently revealed emails show Fauci and NIAID officials “scrambled in April 2020 to answer questions about altering the endpoint” in a trial of remdesivir. Once the drug was declared the new standard of care for COVID-19, as Forbes reported, Gilead’s stock surged more than 16 percent in overnight trading.

Cihlar and Lane had reason to be glad over what Fauci called “quite good news.” In its press release on remdesivir, also known as Veklury, Gilead claims that its FDA-approved drug “can help reduce disease progression across a spectrum of disease severity and enable hospitalized patients to recover faster, freeing up limited hospital resources and saving healthcare systems money.”

Scientific and medical journals were skeptical, to say the least.

As Jon Cohen and Kai Kupferschmidt noted in Science magazine, the European Union cut a deal in October 2020 with Gilead potentially worth $1 billion. Later that month, the U.S. Food and Drug Administration made remdesivir the first drug to receive approved status for COVID treatment.

The European Union settled on remdesivir pricing—$2,400 for a full course—one week before the Solidarity trial, and was unaware of the results. For its part, the Science authors charge, Gilead “knew the trial was a bust.” That didn’t sit well with Scripps Institute cardiologist Eric Topol.

“This is a very, very bad look for the FDA,” Topol told Science, “and the dealings between Gilead and EU make it another layer of badness.” The EU and American decisions, the Science authors noted, “baffled scientists who have closely watched the clinical trials of remdesivir unfold over the past six months—and who have many questions about remdesivir’s worth.”

One study found that remdesivir “modestly reduced the time to recover from COVID-19 in hospitalized patients with severe illness.” Other studies found remdesivir to have “no impact of treatment on the disease whatsoever.” The fourth and largest study, by the World Health Organization, “showed that remdesivir does not reduce mortality or the time COVID-19 patients take to recover.”

The Science authors cite Jason Pogue of the University of Michigan, president of the Society of Infectious Diseases Pharmacists, that the FDA should not have approved remdesivir. There is not enough evidence that remdesivir works and “more questions than answers about the efficacy of remdesivir in hospitalized patients.”

Gary Schwitzer, publisher of HealthNewsReview.Org, found Fauci’s announcement of remdesivir as the standard of care “troubling.” Schwitzer also cited Dr. Eric Topol, who was “unimpressed” by the Gilead drug. As Schwitzer pointed out, “the primary endpoints or outcomes were shifted by the researchers in the NIH trial” (emphasis added). In the middle of that trial, the endpoint was changed from measuring the effectiveness against death and various forms of hospitalization on day 15 to time to recovery through day 29.

For the general public, Schwitzer wrote, “this is somewhat akin to the football field being shrunk so that the goal line is not 100 yards away but only 50 yards away—after the game has already begun.” And it was only after scientists and journalists pointed to evidence that the goalposts had been moved “that any public discussion or explanation was made by the researchers.”

It was this shift that Fauci and his aides scrambled to answer. In his public statement in April 2020, Fauci said the trial results proved remdesivir “can block the virus” that causes COVID-19, but the NIAID boss didn’t mention the change in endpoint. If anybody thought Fauci was rigging the trial to get the outcome he and Gilead wanted, it would be hard to blame them. And it wouldn’t be the first time.

Fauci’s favored treatment for AIDS was AZT (azidothymidine) marketed as Zidovudine. This DNA chain terminator is highly toxic and does not prevent or cure AIDS. Even so, in 1987, the FDA approved AZT at lightning speed, which disturbed molecular biologist Harvey Bialy, then scientific editor of Biotechnology.

“I can’t see how this drug could be doing anything other than making people very sick,” Bialy said. On the other hand, AZT was making some people very rich. At a price of $8,000 per patient per year, AZT was the most expensive drug ever marketed at the time. After FDA approval, Burroughs Wellcome stock went through the roof.

Fauci’s NIAID funded trials of AZT and other dangerous drugs on foster children in New York, nearly all of them African American or Latino. The BBC told the story in the 2004 documentary Guinea Pig Kids. According to one nurse, some 80 children died in the experiments. (For further reading, see Poison by Prescription: The AZT Story, by John Lauritsen.)

Cohen and Kupferschmidt cite a disproportionately high number of liver and kidney problems in patients receiving remdesivir, compared to other drugs. In The Real Anthony Fauci, Robert F. Kennedy, Jr. cites the “toxicity” of remdesivir, Fauci’s “vanity drug.” Remdesivir shows “no clinical efficiency” against COVID, but at approximately $3,000 per treatment, remdesivir is much more expensive than either hydroxychloroquine or ivermectin, treatments that Fauci opposes.

As Kennedy explains, Fauci’s deputy Cliff Lane co-chaired the NIH treatment guidelines panel that supervised the remdesivir trials and stood to share in the patent rewards. So Lane was “doubly conflicted.”

“I am glad for Gilead as well,” Lane told Gilead boss Tomas Cihlar in April 2020. As the Epoch Times noted, “the first part of Lane’s response was redacted,” like other NIAID emails obtained by a FOIA request. Whitecoat supremacists enjoy protection from disclosure, on top of their vast power and privilege.

Meanwhile, as the prophet said, “is there no balm in Gilead?” Not this time, but there is a great deal of money. As Brian Robertson recently explained, “following the money has been the key to uncovering the corruption surrounding COVID-19; now it may be the key to providing a solution to it.”


White House announces new steps to make COVID-19 oral antivirals easier to access

The Biden administration announced new actions it intends to take to expand the country’s infrastructure for testing and treating the coronavirus, including making oral antivirals and preventative options easier to access for everyday Americans.

Senior administration officials at the White House discussed new steps Monday to ramp up distribution capacity, which included nearly doubling the number of places oral antivirals are available, and the new installation of federally-supported test-to-treat sites.

This image provided by Pfizer in October 2021 shows the company's COVID-19 Paxlovid pills. U.S. health regulators on Wednesday, Dec. 22, 2021 authorized the first pill against COVID-19, a Pfizer drug that Americans will be able to take at home to head off the worst effects of the virus. (Pfizer via AP)
This image provided by Pfizer in October 2021 shows the company's COVID-19 Paxlovid pills. U.S. health regulators on Wednesday, Dec. 22, 2021 authorized the first pill against COVID-19, a Pfizer drug that Americans will be able to take at home to head off the worst effects of the virus. (Pfizer via AP) (Pfizer via AP)

"These actions will help strengthen and further build the infrastructure to ensure that lifesaving treatments for COVID-19 are quickly distributed around the country, widely available and easy to access," the officials said.

"To date, the administration has worked with pharmacies, long-term care facilities, community health centers, and other health care settings to establish more than 2,200 tests-to-treat sites around the country, including sites specifically for military families and veterans," the White House added. "As a result, usage of oral antivirals has more than doubled over the last several weeks. But more is needed to make these treatments even easier to access and make sure health care providers and patients know about their safety, efficacy and availability."

The White House also specified its intention to support medical providers with more guidance and tools to understand and prescribe treatments, and to communicate these new safe treatment options to the American people.

First on the Biden administration’s agenda is to nearly double the places where oral antivirals can be accessed, a process which could take several weeks.

"Starting this week, the administration will allow all pharmacy partners in the federal antivirals pharmacy program representing tens of thousands of pharmacy locations nationwide to order free antiviral treatments directly from the federal government," officials said.

These pharmaceutical drugs will soon be available in more than 30,000 locations, a number the administration hopes to swell to 40,000 through a partnership between the Department of Health and Human Services and its pharmacy partners, it said.

One specific oral antiviral the administration is looking to swiftly move into circulation is Pfizer’s pill Paxlovid.

The administration described the pill as "the most effective available treatment… which has been shown to reduce the risk of hospitalization or death by about 90%."

"The U.S. has committed to purchase 20 million treatment courses—more than any other country in the world," it added.

Next, the Biden administration also intends to expand federally-supported COVID-19 tests-to-treat sites, working alongside state governments, local health agencies, and their respective jurisdictions to ensure wide availability.

"These sites will be targeted to meet demand and increase equitable access to lifesaving COVID-19 treatment and will function in direct collaboration with state and local health agencies," officials said.

Lastly, the administration intends to keep healthcare providers across the country informed on the latest effective prescription of COVID-19 treatments, as well as patient side effects and risk factors.

"The administration has been working for months with health care providers around the country to inform them about new treatments with weekly webinars, with state and territorial health officials, health care and medical organizations," the White House said. "The administration will continue actively engaging the clinical community to broaden awareness and understanding of these treatments and to make sure that health care providers are counseling their patients about these effective treatments, prescribing them when appropriate and helping patients identify where their prescription can be filled."

These additional measures, however, will require securing additional funding from Congress, the administration said.




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