Friday, June 30, 2023


I managed my seasonal virus better than I expected yesterday and managed to put up something interesting on all my blogs. I seem to be on track to do that today as well


COVID-19 can cause brain cells to 'fuse'

Researchers at UQ have discovered viruses such as SARS-CoV-2 can cause brain cells to fuse, initiating malfunctions that lead to chronic neurological symptoms.

Professor Massimo Hilliard and Dr Ramon Martinez-Marmol from the Queensland Brain Institute have explored how viruses alter the function of the nervous system.

SARS-CoV-2, the virus that causes COVID-19, has been detected in the brains of people with ‘long COVID’ months after their initial infection.

“We discovered COVID-19 causes neurons to undergo a cell fusion process, which has not been seen before,” Professor Hilliard said.

“After neuronal infection with SARS-CoV-2, the spike S protein becomes present in neurons, and once neurons fuse, they don’t die.” They either start firing synchronously, or they stop functioning altogether.”

As an analogy, Professor Hilliard likened the role of neurons to that of wires connecting switches to the lights in a kitchen and a bathroom.

“Once fusion takes place, each switch either turns on both the kitchen and bathroom lights at the same time, or neither of them,” he said. “It’s bad news for the two independent circuits.”

The discovery offers a potential explanation for persistent neurological effects after a viral infection.

“In the current understanding of what happens when a virus enters the brain, there are two outcomes – either cell death or inflammation,” Dr Martinez-Marmol said. “But we’ve shown a third possible outcome, which is neuronal fusion.”

Dr Martinez-Marmol said numerous viruses cause cell fusion in other tissues, but also infect the nervous system and could be causing the same problem there.

“These viruses include HIV, rabies, Japanese encephalitis, measles, herpes simplex virus and Zika virus,” he said.

“Our research reveals a new mechanism for the neurological events that happen during a viral infection.

“This is potentially a major cause of neurological diseases and clinical symptoms that is still unexplored.”

The research was published in Science Advances.


Italian Bombshell—COVID-19 mRNA Vax Cardiac Problems ‘Not Uncommon’

Research led by Italian physician-scientists, including corresponding author Nino Cocco at Campus Bio-Medico University of Rome, Department of Cardiovascular Sciences and Francesco Pelliccia, Ph.D., Sapienza University of Rome shows mounting concerns associated with the COVID-19 mRNA vaccines.

Sharing that “several patients” complained of heart palpitations or even worse arrhythmic events after receiving an mRNA COVID-19 vaccine in their specific clinical practice, the research collective sought to undertake a literature review of post-COVID-19 vaccine heart rhythm disorders which turned up several instances of heart rhythm disorders after mRNA COVID-19 vaccination.

Noteworthy, biomedical researchers from both Italy and Switzerland found this problem with other vaccines in addition to the COVID-19 products. Importantly, in regard to COVID-19 mRNA vaccines, the study authors call out that serious adverse events are ‘not uncommon” and demand clinical and scientific attention now.


While mass vaccination against SARS-CoV-2, the virus behind COVID-19, was considered collectively the best way to fight the COVID-19 pandemic, and generally, these products helped reduce cases of morbidity and mortality, the Italian-led team reports a troubling concern. They state that “side effects are being reported more frequently as more and more people around the world become treated.”

While the mRNA products are deemed “safe and effective” by regulatory bodies, the study team here emphasizes the importance of not underestimating “other side effects” in addition to the predominant risk of myopericarditis.

Key findings

Reporting on case series of patients affected by cardiac arrhythmias post-mRNA vaccine from their own clinical practice, the Italian-led team evaluate the literature. Reviewing the official vigilance database, Dr. Coco and colleagues report that “heart rhythm disorders after COVID vaccination are not uncommon and deserve more clinical and scientific attention.”

This assessment represents a distinct change in direction as most physician-scientists continue to downplay the linkages between the COVID-19 mRNA vaccines and various cardiovascular and other disorders linked to the novel products.

While the study authors continue to support the use of mRNA technology, arguing in their paper published in the International Journal of Molecular Sciences that “the risk-benefit ratio” remains “clearly in favor of vaccination,” they posit that linked “heart rhythm disorders are not a negligible issue, and there are red flags in the literature about the risk of post-vaccination malignant arrhythmias in some predisposed patients.”

The authors raise questions about the impact of COVID-19 vaccines on heart conduction. They also review possible molecular pathways for the COVID-19 vaccines to impact cardiac electrophysiology and cause heart rhythm disorders.


Super fit mother-of-two, 37, 'is left in chronic pain, bound to a wheelchair and forced to find a new home' after Covid jab

A mother-of-two claims she has been left in debilitating pain and now relies on a wheelchair to get around after receiving three doses of a Covid vaccine.

Mel Guevremont, 37, says she has gone from being a keen gym-goer, surfer, snowboarder and rock climber to barely being able to take a few steps around her home before her legs give out.

Ms Guevremont, from Sydney, claims her body has broken down and she has been forced to wear a neck brace since receiving her third Pfizer mRNA vaccine in March 2021.

'It's ruined my life completely and utterly,' she told Daily Mail Australia.

'I am skin and bones. I don't recognise myself. It's not my body and I wake up with a new symptom every day. It's a grieving process.'

Ms Guevremont and her partner Richard Ellison, who moved to Australia from Canada seven years ago, said they were forced to sell their Manly unit because it was located on the fourth floor and she struggles with stairs.

They now live with their two boys in a ground-level home in the south-eastern Sydney suburb of Maroubra.

Ms Guevremont said she has spent more than $25,000 seeing specialists, including neurologists and rheumatologists, but has not found them helpful.

Mel Guevremont says she has been left in a wheelchair after three doses of the Covid vaccine

Her comments come after a landmark Covid vaccine injury class-action lawsuit was filed in April against the Australian government, the Therapeutic Goods Administration (TGA) and the Department of Health.

The nationwide suit, which reportedly has 500 members, seeks redress for those allegedly left injured or bereaved by the Covid vaccines.

Ms Guevremont said she was a fit and healthy woman who regularly took part in outdoor activities - but her active lifestyle has drastically changed.

'Right before these jabs I was snowboarding in New Zealand. The only problem I had was a tweaked knee from too much surfing and playing basketball,' she said.

'I was an adrenaline junkie. I did not stop. It's quite the clash for me to be barely able to hold a cup of coffee or hold my own neck.

'How do you go from snowboarding, ripping on a mountain and having a great time, to all of a sudden can't hold your neck?'

Ms Guevremont claims she is also suffering from electric shocks, unexplained weight loss and body weakness.

'I went to a beauty salon and after a while I couldn't feel my legs,' she said. 'When I tried to get up, my legs just completely collapsed. I sort of laughed and brushed it off. 'I thought maybe it was related to post-pregnancy hormones.'

Ms Guevremont says she struggles to do basic physical activities like walk to the park or even pick up her two boys, who are aged two and four.

'It breaks my heart. My young one wants to play soccer, and he knows I played soccer with him before, and all of a sudden I can't,' she said. 'I wonder if I am going to be there for my kids.'

The mother has made farewell videos for her boys just in case she is 'not around' when they grow older.

In July 2021, Ms Guevremont caught Covid-19, which she said took her four days to get over, after which 'she was fine'.

In November 2021, her condition spiralled and she fainted and collapsed. 'My partner rushed me to the hospital and I stayed there for a week,' she said.

She said a specialist suggested she might have 'post-vaccination syndrome and potentially post-viral syndrome' - although she only wrote the second diagnosis in her notes.

In referrals seen by Daily Mail Australia, hospitals and neurologists have diagnosed Ms Guevremont with 'suspected vaccine injury'.

Last year, Ms Guevremont reported herself as a vaccine injury to the TGA but said she was still waiting for a response. 'They fail to follow up and investigate,' she said.

A TGA spokesperson told Daily Mail Australia an 'acknowledgement email requesting further information was sent in response to an adverse event report submitted by Ms Guevremont'.

They added: 'The TGA strongly encourages vaccine recipients and healthcare professionals to report their experience of suspected adverse events, even if there is only a very small chance a vaccine was the cause.

'The TGA uses these reports to look for patterns in reporting that may indicate a new safety signal for a vaccine.'

The spokesperson said such a signal will lead 'to appropriate regulatory action which may include making changes to a vaccine's Product Information and communicating information to doctors.

'To date, the TGA has initiated over 43 regulatory actions to include new safety information in Product Information documents,' the TGA representative said.

But Ms Guevremont said she felt 'abandoned' and turned to Kerryn Phelps, the former head of the Australian Medical Association, for help.

Last December, Professor Phelps told a parliamentary inquiry into long Covid that both she and her wife had been vaccine-injured.

Ms Guevremont said Professor Phelps was very kind and supportive in referring her to a neurologist who 'specialised in vaccine injuries' but who turned out to be too busy to see her.

She also condemned the vaccine-injury compensation scheme run by Services Australia. 'The compensation scheme is a joke,' she said.

The compensation scheme for Pfizer vaccines includes about 10 eligible conditions, but these don't include neurological conditions such as Guillain-Barre Syndrome and Transverse Myelitis, even though they are listed for AstraZeneca shots.

'The TGA and regulators around the world continue to monitor and analyse Covid-19 vaccine safety data covering hundreds of millions of people, and the latest evidence from clinical trials and peer-reviewed medical literature,' the TGA spokesperson said.

'This information continues to overwhelmingly support the safe and effective use of Covid-19 vaccines.

'It remains the consensus view of international regulators and health departments that the benefits of Covid-19 vaccination continue to far outweigh the rare risks.'

Ms Guevremont is currently looking at experimental treatments and possibly moving the U.S. to receive them.




No comments: