Wednesday, November 10, 2021



Promising new covid test

A Breathalyzer-type test that can detect COVID-19 within seconds is currently being tested and could become a noninvasive, rapid alternative to nasal swab tests, according to researchers.

COVID-19 infection causes a distinct breath print from the interaction of oxygen, nitric oxide, and ammonia in the body. An initial study of the breath test found that it gave accurate results for COVID-19 infections in almost 90% of critically ill patients with the disease.

The breathalyzer test can detect COVID-19 in exhaled breath within 15 seconds, according to researchers who have applied to the U.S. Food and Drug Administration for emergency use authorization.

The study included 46 intensive care patients with acute respiratory failure who required mechanical ventilation. All of the patients had a PCR COVID-19 (nasal swab) test upon admission to the ICU, half were found to have COVID-19.

The researchers collected exhaled breath bags from all of the patients on days 1, 3, 7, and 10 of their hospitalization, the samples were tested within four hours after collection.

The testing proved to be 88% accurate in detecting the breath print of COVID-19, according to the study published Oct. 28 in the journal PLOS ONE.

"The gold standard for diagnosis of COVID-19 is a PCR test that requires an uncomfortable nasal swab and time in a lab to process the sample and obtain the results," said lead researcher Dr. Matthew Exline, director of critical care at Ohio State University Wexner Medical Center.

"This novel [Breathalyzer-type] technology uses nanosensors to identify and measure specific biomarkers in the breath," said test co-developer Pelagia-Irene Gouma, a professor in Ohio State's Department of Materials Science and Engineering and Department of Mechanical and Aerospace Engineering.

"This is the first study to demonstrate the use of a nanosensor [Breathalyzer-type] system to detect a viral infection from exhaled breath prints," Gouma said in an Ohio State news release.

"PCR tests often miss early COVID-19 infections and results can be positive after the infection has resolved," Exline said in the release. "However, this noninvasive breath test technology can pick up early COVID-19 infection within 72 hours of the onset of respiratory failure, allowing us to rapidly screen patients in a single step and exclude those without COVID-19 on mechanical ventilation."

The researchers plan to further assess the use of the technology to detect less severe COVID-19, as well as other infections and diseases.

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Fauci Orders Parents to Vaccinate Kids, Regardless of Concerns on Safety and Efficacy

National Institute of Allergy and Infectious Diseases director Dr. Anthony Fauci told parents on Wednesday that they can ask questions about the safety and efficacy of the coronavirus vaccine, but that they need to get their kids vaccinated regardless.

Doesn't that defeat the purpose of asking questions? We reserve the right to decide what is injected into our bodies.

"Children statistically, when they get infected they do not get the incidence of severe disease to the level of adults, particularly elderly do," Fauci said on CNN. "There have been about 700 deaths in the younger age group. But children are vulnerable. They can get infected. They also can spread the infection once they get infected within the family unit. So there are a lot of reasons to get the children vaccinated."

"There's no indication whatsoever, even any feasibility that would affect fertility at all," he continued. "In fact, in the millions and millions of doses and billions of doses that have been given worldwide of the vaccine, there is no indication whatsoever that it has anything to do with fertility. Giving it to a child, you have to look for a plausible mechanism of what that would be, and there is none."

Fauci said, "We will hit the ground running. Probably by the beginning of next week, we will be at full speed. So parents should consult with their pediatricians, family physicians, pharmacists and they will be able to know exactly where to get this particular vaccine for their children, from 5 to 11."

"We want to get out of the pandemic phase and into a good, controlled phase," he added. "There are different levels of approach and control of a particular outbreak...I don't think we're going to get to eradication. We only eradicated one viral disease and that's smallpox. But you can get it down to a very low level if you get enough people vaccinated, and a low level is one that doesn't interfere with how we function in society."

Despite what Fauci preaches, vaccines are not the answer to everything.

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Australian regulator requests information from Pfizer after British medical journal alleges contractor ‘falsified’ safety data

Australia’s medicines regulator has sought additional information from Pfizer after an investigation by the British Medical Journal alleged serious issues with a small number of its vaccine safety trials, including claims of “falsified data” and slowness following up on adverse reactions.

The Therapeutic Goods Administration (TGA) has stressed that Pfizer’s vaccine is “highly safe and effective”, and that Australians “should not be concerned about the issues raised in the article”.

The BMJ’s report, published last week, centred on a former employee of Ventavia Research Group, a Texas-based contractor involved in the phase-three trials for Pfizer’s Covid vaccine last year.

According to Brook Jackson, a former regional director at Ventavia, the company “falsified data, unblinded patients, employed inadequately trained vaccinators, and was slow to follow up on adverse events”, the BMJ reported.

The whistleblower, who provided the BMJ with “dozens of internal company documents, photos, audio recordings and emails”, recounted that she repeatedly notified the company of the problems before finally emailing a complaint to the US Food and Drug Administration on September 25, 2020.

She was sacked the same day, with the company saying in her separation letter she was “not a good fit”.

In a statement to The Conversation, Ventavia said Ms Jackson was employed for “approximately two weeks” in September of 2020 and “no part of her job responsibilities concerned the clinical trials at issue”.

Ventavia said the “same accusations” were investigated and “determined to be unsubstantiated” last year.

Pfizer’s full phase-three trial involved about 44,000 participants across 153 sites. Ventavia enrolled more than 1000 participants at three sites – or only around 2 per cent of the total.

The drug company made no mention of the alleged problems at the Ventavia sites in a briefing document submitted to an FDA advisory committee meeting on December 10, 2020.

The FDA, which never audited Ventavia after receiving the complaint, issued its emergency use authorisation for the vaccine the next day.

A Pfizer Australia spokeswoman declined to comment on the BMJ report.

News.com.au understands the TGA has contacted Pfizer to further clarify the issues raised, although given the allegations only pertain to 2 per cent of the trial population, the overall results are not expected to be impacted.

“The Pfizer Covid-19 vaccine is highly safe and effective and has been approved for use in nearly 100 countries and also approved by the World Health Organisation,” a TGA spokeswoman said.

“Australians who have received the Pfizer vaccine should not be concerned about the issues raised in the BMJ article.”

She noted that “the safety and efficacy of the Pfizer Covid-19 vaccine demonstrated in clinical trials has been thoroughly substantiated by real-world use in many millions of people worldwide”.

“The benefits of vaccination are clear and not in dispute,” she said.

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IN BRIEF

Gloomy landscape for Democrats in midterms as Joe Biden’s approval drops to 38% (USA Today) | “I didn’t run because of the polls”: Scranton Joe brushes off lagging poll numbers (Fox News)

Pete Buttigieg says administration will use “infrastructure” bill to address “racist” highway design (Daily Wire)

“Stay angry”: Barack Obama scolds us on climate from Glasgow (Reuters) | Obama’s climate speech is a reminder of how badly he governed (The Federalist)

House January 6 committee inquisition issues subpoenas to six top Trump advisers (Washington Post)

Authoritarian White House encourages businesses to prepare for vaccine mandate despite court injunction (National Review)

Woke U.S. Navy names ship after accused pedophile Harvey Milk (PM)

Illegal alien who allegedly murdered father of four “was on one of Biden's flights” (Daily Wire)

China’s navy is now world’s largest with 460 warships by 2030 (Washington Times)

That’s ominous: China builds mockups of U.S. Navy ships in area used for missile target practice (Reuters)

Justice Department seizes $6 million as part of crackdown on hackers linked to Kaseya attack (The Hill)

You know those cargo ships and trains waiting to be unloaded in California? Yeah, now homeless people are breaking in and stealing things from the stopped trains. (Not the Bee)

Consumer group attacks BlackRock for hypocrisy by investing in Chinese companies (Washington Times)

Nineteen-year-old wins New Jersey school board election after his senior year was ruined by COVID policies (Not the Bee)

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Tuesday, November 09, 2021


Note

I have received a couple of notices from blogger.com saying that some of my posts have been depublished on the grounds that I was spreading misinformation. My post of 22 August was particularly mentioned. It was a rather extreme post so I am not too bothered by its loss.

What is not clear is whether today's post is visible to readers. It starts with a media report about Sweden. I would be obliged if people would let me know if they can see it. My email is jonjayray@hotmail.com

The second post today was about an alternative way to medicate covid so maybe that was the problem. I have deleted it but will keep a record of it

UPDATE: Many readers have confirmed that they have seen the post below about Sweden. I will post the expunged post somewhere else in due course. Its claims that a certain treatment could be a useful palliative for people infected by covid seemed well supported by scientific studies but it was a bit unorthodox.

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How Sweden's lockdown gamble paid off: Nation has suffered fewer coronavirus deaths than most of Europe and has a lower infection rate

Sweden has suffered fewer Covid deaths than most of Europe and is still recording lower infection rates, according to figures that suggest its lockdown gamble has paid off.

The Scandinavian nation became an international outlier last year when it defied scientific advice and refused to follow the rest of the world in shutting down society to curb the virus' spread.

Not only has Sweden's economy bounced back faster than any other country in the EU, latest data shows that it has also fared better than most in terms of lives lost during the pandemic.

Sweden has suffered almost 1,500 confirmed Covid deaths per million people, according to Oxford University-based research platform Our World in Data, which is lower than the European average (1,800).

The UK — which has endured three national lockdowns and several regional fire-breakers — has recorded 2,100 per million, for comparison, while Belgium and Italy both have rates above 2,000.

When looking at excess mortality during the pandemic, Sweden ranks just 21st out of 31 European countries with 5 per cent more deaths since March last year than would be expected. Britain, Italy and Spain, on the other hand, have each suffered around 10 per cent more deaths than average during Covid.

Statisticians say excess mortality is the most accurate way to measure the toll of the pandemic on health because it accounts for testing disparities between countries and includes knock-on fatalities.

Sweden also has a lower infection rate currently than most EU nations, with just 100 per million people testing positive daily compared to 800 in Austria, nearly 700 in Belgium and Ireland, and 500 in the UK.

Although Sweden chose not to lock down completely early in the pandemic, it did introduce stricter legally-binding curbs last winter as cases and deaths rose.

These included a ban on groups of eight or more people, limits on numbers in gyms and shops and an 8pm curfew on pubs and restaurants.

While Sweden appears to fared done better than continental Europe during the pandemic, it has performed significantly worse when compared to its closest neighbours.

Norway and Finland, for example, have suffered about 200 Covid deaths per million people since the virus was first seeded on the continent — seven times lower than Sweden's toll.

In Denmark the rate is around 400. All three nations have had tougher restrictions during much of the pandemic, which are likely to have played a role.

When looking at excess mortality, Norway and Denmark have recorded fewer deaths than normal during Covid and Finland has seen little over 1 per cent more fatalities than average.

Cambridge University epidemiologist Raghib Ali told MailOnline: 'Whether you think Sweden's strategy was a success story comes down to which countries you compare it to.

'If you think it should have a similar rate [of Covid deaths] to its neighbours Finland, Norway and Denmark or other countries like Germany and the Netherlands?

'Whichever side you come down on decides whether it did better or worse.'

Dr Ali said that one takeaway from Sweden's voluntary lockdown system was that it shows the power of people's small behavioural changes.

'Although Sweden didn't have a Government-enforced lockdown, it did have a type of voluntary lockdown that was well-adhered to.

'What we've learned from Sweden - and the UK - is that people's voluntary behaviour can get countries over a peak without mandated restrictions, even though they alone cannot prevent big outbreaks.'

It comes as daily Covid infections in the UK continued to plummet today, bolstering hopes that the third wave may have already peaked.

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Monday, November 08, 2021



Note

I have just put up on my Food & Health blog details of another study showing that alcohol is good for you

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Scientists say 'suctioning'' vaccines generates more antibodies

A 'suctioning' technique for COVID-19 vaccines may be able to provide more protection than traditional needles, a new study suggests.

Researchers tested a new type of immunization for the virus based on the ancient form of medicine known as cupping, in which heated special cups are placed on the skin for a few minutes to create suction, immediately follow a Covid shot.

They found rodents that were given the vaccine via the suction method generated antibody levels millions of times higher than a traditional injection.

The team, from Rutgers University in New Brunswick, New Jersey, says a suctioning vaccine is faster and cheaper to manufacture, and can be more widely distributed than the vaccines currently in use.

'This suction-based technique is implemented by applying a moderate negative pressure to the skin after nucleic acid injection in a totally non-invasive manner,' said senior author Dr Hao Lin, a professor in the department of mechanical and aerospace engineering at Rutgers, in a statement.

'This method enables an easy-to-use, cost-effective and highly-scalable platform for both laboratory and clinical applications for nucleic-acid-based therapeutics and vaccines.'

The team noted that with traditional vaccines, when they are injected into the arm, they are not automatically absorbed by cells.

In fact, some of it degrades before it even gets to the cells so the body can mount an immune response.

But by providing suction on the skin immediately after the shot, researchers theorized this would create strain on the skin, forcing cells to automatically absorb the vaccine.

For the study, published in the journal Science Advances, they decided to test this theory using the ancient practice of cupping.

Cupping uses special cups, which are often heated, to create suction and pull blood into the skin.

Proponents say it helps increase blood flow, relieves pain, cure headaches and treat other ailments.

A COVID-19 vaccine candidate was provided by GeneOne Life Science, a biopharmaceutical company based in Seoul, South Korea.

One group of rats received two injections of the vaccine, another group received a single injection followed by a single suction and a final group received two injections followed by two suctions.

Antibody levels were between two million and five million times higher among the two suction groups than the group that received injections alone, results showed.

'We have demonstrated an alternative, safe and effective transfection platform that yields high levels of transgene expression,' Lin said.

'The advantages also include device cost-effectiveness and manufacturing scalability and minimal requirements for user training.

'Because of the inherent advantages of DNA, not least of which is avoiding cold-chain requirements of other vaccines, this technology facilitates vaccination programs into remote regions of the world where resources are limited.'

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Pfizer linked to 18 new cases of heart inflammation in Australia

The number of cases of heart inflammation in Australia linked to the Pfizer vaccine has risen to 253 from about 21.9 million doses.

There were 18 new likely cases of myocarditis in the past week, a condition that sees patients experience chest pain, abnormal heartbeat and shortness of breath.

One new blood clots case linked to the AstraZeneca jab was also recorded, taking the total to 158 cases and nine deaths in Australia from about 13.1 million doses. The confirmed case involved a 40-year-old man from NSW.

The figure was released in the Therapeutic Goods Administration Covid-19 vaccine weekly safety report on Thursday afternoon.

The youngest case classified as ‘likely myocarditis’ to date was 12 years old.

Of the cases classified as likely to be myocarditis, most of the patients experienced symptoms within three days of vaccination.

Around half of the patients were admitted to hospital with eight treated in intensive care. Most patients treated in hospital were discharged within four days.

The TGA says “the estimated reporting rates in Australia appear similar to overseas rates.”

“As we have received limited adverse event reports for Spikevax (Moderna), our analysis of likely myocarditis cases focuses on data for the Comirnaty (Pfizer) vaccine,” the medicines regulator said.

In Australia, myocarditis is reported in nearly one out of every 100,000 people after receiving the Pfizer vaccine. While it is more commonly reported in young men and teenage boys after the second dose (6.7 cases in 100,000 people) it remains rare.

Cases usually occur within 10 days and resolve after a few days following treatment and rest.

The TGA advises people to seek medical attention if they experience symptoms that could suggest myocarditis or pericarditis.

This includes: chest pain, palpitations (irregular heartbeat), fainting or shortness of breath, particularly if they occur within one to five days of vaccination.

“ATAGI advises that people who develop myocarditis or pericarditis attributed to their first dose of Comirnaty (Pfizer) should defer further doses of an mRNA Covid-19 vaccine and discuss this with their treating doctor,” the TGA says.

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U.S. federal appeals court freezes Biden's vaccine rule for companies

A U.S. federal appeals court issued a stay Saturday freezing the Biden administration's efforts to require workers at U.S. companies with at least 100 employees be vaccinated against COVID-19 or be tested weekly, citing "grave statutory and constitutional" issues with the rule.

The ruling from the United States Court of Appeals for the Fifth Circuit comes after numerous Republican-led states filed legal challenges against the new rule, which is set to take effect on Jan 4.

The White House declined to comment on the ruling, and referred questions to the Labor Department, where spokespeople did not immediately respond to a request for comment.

The stay comes two days after the Biden administration unveiled the rule, which was immediately met with vows of legal action from Republican governors and others, who argued it overstepped the administration's legal authority.

The action on the private-sector vaccinations was taken under the U.S. Occupational Safety and Health Administration's (OSHA) emergency authority over workplace safety, officials said. The rule applies to 84.2 million workers at 1.9 million private-sector employers, according to OSHA.

Saturday's court order came in response to a joint petition from several businesses, advocacy groups, and the states of Texas, Louisiana, Mississippi, South Carolina and Utah. The rule is also facing separate legal challenges before other courts.

The two-page order directs the Biden administration to respond to the request for a permanent injunction against the rule by 5pm Monday.

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Gov. Stitt Sticks it to Biden: 'There Will Be No Government Vaccine Mandates In Oklahoma'

Oklahoma Governor Kevin Stitt stuck it to President Joe Biden and his unconstitutional vaccine mandates, declaring that it is a "complete disregard for individual freedoms and states’ rights." Stitt added that he intends to fight the order.

“It is not the government’s role to dictate to private businesses what to do. Once again President Biden is demonstrating his complete disregard for individual freedoms and states’ rights. As long as I am governor, there will be no government vaccine mandates in Oklahoma. My administration will continue to defend Oklahoma values and fight back against the Biden administration’s federal overreach," he said.

News on 6 reports:

It's too early for a lot of companies to know what this means and how it'll be enforced, but Oklahoma Representative Kevin Hern was quick to point out the problems with what he calls a huge federal overstep.

"This looks like Putin or Xi Jinping, how they operate. He's trying to push this out there and that's what dictators do," Hern said.....

The Oklahoma Attorney General John O'Connor and the Republican National Committee both said, separately, that they are pursuing litigation against Biden's mandate, claiming it is unconstitutional and an overreach of federal government.

According to Oklahoma Commerce Department, 1,962 companies employ over 100 people in Oklahoma meaning that the federal requirements will impact 678,122 Oklahomans. Oklahoma Senator James Lankford and Representative Kevin Hern issued similar rebukes of the President.

“My family and I chose to receive a COVID-19 vaccine, and I am grateful for it. Every Oklahoman and American should have that same choice and option. Federal employees and contractors, members of our military, health care workers, and everyone else in our nation should be able to choose whether to get vaccinated. Period. The Biden proposal ignores the natural immunity millions of Americans have because they have recovered from COVID and the millions of other Americans that do not want to be forced to take a vaccine for a multitude of personal, religious, and medical reasons,” Lankford explained.

“The federal government has once again overstepped into the lives and livelihoods of American citizens,” Hern added. “Private companies, especially small businesses, are already suffocating under the oppressive restrictions put in place at the start of the public health emergency last year. My colleagues and I have warned of the slow march to socialism for years, and we were called liars for it. Turns out it’s not so much a slow march as it is a sprint. More restrictions, more mandates, more socialist policies are never the answer.”

Oklahoma AG O'Connor declared, "We respect the right of Oklahoma businesses and individuals to make healthcare decisions for themselves and their families. My office will vigorously oppose any attempt by the federal government to mandate vaccines. We are preparing litigation to stand up for our rights and defend the rule of law against the overreach of the federal government."

The RNC Chairwoman Ronna McDaniel stated, “Joe Biden told Americans when he was elected that he would not impose vaccine mandates. He lied. Now small businesses, workers, and families across the country will pay the price. Like many Americans, I am pro-vaccine and anti-mandate. Many small businesses and workers do not have the money or legal resources to fight Biden’s unconstitutional actions and authoritarian decrees, but when his decree goes into effect, the RNC will sue the administration to protect Americans and their liberties.”

Oklahoma House Speaker Charles McCall added, “The Oklahoma Legislature acted aggressively this session to stop unconstitutional federal overreach like President Biden proposed today. We saw this coming and are already prepared to block it in Oklahoma. This type of unilateral overreach is precisely why House Bill 1236 and the additional litigation funds for the attorney general were such big priorities this session. I applaud the attorney general for utilizing the tools the Legislature provided to defend Oklahoma’s rights as a state. President Biden is about to see the U.S. Constitution still matters in Oklahoma. This isn't the only unconstitutional Biden administration action Oklahoma needs to challenge. Our country is a republic of states, not a monarchy, and the president does not have the constitutional authority to issue these type of edicts.”

In other words, Oklahoma isn't playing this communist, tyranny bull crap.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Sunday, November 07, 2021



Effectiveness of vaccines against infection less than 50% on average

But good at preventing death

The protection that fully vaccinated Americans have against COVID-19 infection severely drops over time, a new study suggests.

A team led by the Public Health Institute in Oakland, California, found that the overall effectiveness of the three Covid vaccines available in the U.S fell from 87 percent in March to 48 percent by September.

Johnson & Johnson vaccine recipients are especially at risk with just 13 percent efficacy against contracting the virus.

However researchers found that the shots are still highly protective against death from Covid.

Researchers, who published their findings on Thursday in the journal Science, gathered data from the Veterans Health Administration from February to October 2021.

In total, nearly 800,000 veterans' data was included in the massive study.

The team analyzed vaccine records among people who tested positive for the virus, and determined, on average, how effective each individual jab was at preventing infection.

In February, when the vaccines were still relatively new, they all had an effectiveness of more than 85 percent at preventing infection.

J&J's vaccine saw its protection wane the most, dropping from 86 percent in March to below 50 percent by September, and down to only 13 percent last month.

The Pfizer-BioNTech jab - which is far and away the most commonly used in the U.S. - saw its effectiveness drop from 87 percent in March to 43 percent in September.

September was the first month during which the effectiveness of Pfizer's vaccine dropped below 50 percent.

Moderna's shot held up the best, and is the only one of the three to still be more than 50 percent effective.

The shot's effectiveness has still fallen greatly, though, from 89 percent in March to 58 percent in September.

Overall, the three vaccines' effectiveness was 87.9 percent in March, and dropped to 48.1 percent in September.

'By July 2021, the U.S. experienced a surge in cases of COVID-19, dominated by the [Delta] variant,' the researchers wrote.

'Initial reports, including follow-up of the Pfizer-BioNTech and Moderna trials, suggested sustained vaccine protection, but three reports of the U.S. Centers for Disease Control in August 2021 demonstrated protection against infection had declined in mid-summer as the Delta variant rose to dominance.

'Protection against hospitalization and death remained high. Breakthrough infections, illness, hospitalizations, and deaths have since continued to emerge in vaccine recipients.'

This waning immunity is the source behind the federal goverment's push for Covid vaccine boosters for all Americans.

Last month, additional shots of the vaccines became available to Americans over the age of 65 with severe comorbidities or who have a job that puts them at risk of virus exposure.

The goal behind the booster rollout is to shore up immunity from the virus and prevent breakthrough infections.

Many opposed the booster rollout, though, because the shots are still effective at preventing death from the virus.

The new study found that an unvaccinated person under the age of 65 is 2.6 percent likely to die from the virus, while that risk drops to 1.6 percent with vaccination.

Those who received the Pfizer shot had their risk of death slashed by 84 percent, the most effective of the three.

The Moderna shot reduced risk of death by 82 percent and the J&J by 73 percent. The numbers are even more drastic for people over the age of 65.

For the elderly, risk of death from Covid if unvaccinated is over 20 percent. Fully vaccinated people over the age of 65 only died from the virus nine percent of times, the researchers found.

The Moderna shot was most effective at preventing death among people 65 and older, reducing risk by 75 percent.

The Pfizer shot reduced the elderly's risk of death by 70 percent and the J&J did by 52 percent.

The death rate among fully vaccinated people over 65 is still high, though, underscoring why health officials are targeting boosters at that group in particular.

The Centers for Disease Control and Prevention reports that more than 21 million Americans have received a COVID-19 booster shot, with a majority opting for the Pfizer shot.

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Pfizer's at-home Covid pill 'cuts risk of dying by nearly 90%'

First Merck and now Pfizer

Pfizer today claimed its at-home Covid pill cuts the risk of severe illness by nearly 90 per cent, potentially providing the UK with another weapon in its arsenal to combat the pandemic.

Its twice-a-day antiviral was shown in clinical trials to slash the risk of hospitalisation or deaths by 87 per cent in vulnerable and elderly patients.

The pharmaceutical giant stopped its study of the drug — known as Paxlovid — early due to the 'overwhelming efficacy'.

The findings appear to surpass those seen with Merck's rival pill molnupiravir, which data showed halved the risk of death or hospitalisation.

Paxlovid can be taken at home and is a combination of an experimental drug with an older antiviral called ritonavir, already used to treat HIV/AIDS.

Pfizer described its findings as a 'game-changer' and now plans to apply for approval from American medical regulators in the coming days. The firm will likely also seek approval in the UK, where the Government has already purchased 250,000 courses.

It comes after Britain yesterday became the first country in the world to give Merck's antiviral the green light, paving the way for it to be rolled out on the NHS within the next few weeks.

Announcing the findings, Pfizer's chief executive Albert Bourla said: 'Today's news is a real game-changer in the global efforts to halt the devastation of this pandemic.

'These data suggest that our oral antiviral candidate, if approved or authorized by regulatory authorities, has the potential to save patients' lives, reduce the severity of Covid infections, and eliminate up to nine out of ten hospitalizations.'

Pfizer's drug, part of a class known as protease inhibitors, is designed to block an enzyme the coronavirus needs in order to multiply.

It is given with ritonavir to make sure it stays active in the body for a longer period of time.

Merck's molnupiravir has a different mechanism of action designed to introduce errors into the genetic code of the virus.

It's hoped that the drug will be bulletproof against new variants because it targets an enzyme produce in the body.

Pfizer's drug is part of a class known as protease inhibitors. It is designed to block an enzyme the coronavirus needs in order to multiply. Like protease inhibitors used to treat HIV, it is given in combination with other antivirals.

How effective is it?

A recent trial of the pill in more than 1,200 found that it cut hospitalisation and death rates by 87 per cent in people at high risk of a severe illness from Covid.

It should be given as soon as possible after catching Covid, ideally within three to five days.

Vaccines, which are being made slightly weaker by new strains of the virus, work by targeting the spike protein and were designed to tackle the original virus.

Because a lot of evolution happens on the spike protein, the immune systems of vaccinated people sometimes find it more difficult to recognise new variants.

Pfizer said Paxlovid works best when given to a patient within three days of testing positive.

The study of the pill included around 1,200 patients who were mostly vaccinated and had recently tested positive.

It looked at patients with at least one risk factor for developing severe disease, such as obesity or older age.

It found that 0.8 per cent of those given Pfizer's drug were hospitalised and none had died by 28 days after treatment.

For comparison, the hospitalisation rate stood at 7 per cent for the patients given a placebo. There were also seven deaths in the placebo group.

Annaliesa Anderson, head of the Pfizer programme, said: 'We saw that we did have high efficacy, even if it was five days after a patient has been treated.

'People might wait a couple of days before getting a test... and this means we have time to treat people and really provide a benefit from a public health perspective.'

The company did not detail side effects of the treatment, but said adverse events happened in about a fifth of both treatment and placebo patients.

Pfizer is also studying whether its pill could be used by people without risk factors for serious Covid as well as to prevent coronavirus infection in people exposed to the virus.

Health and Social Care Secretary Sajid Javid said: 'Incredible results from Pfizer showing their antiviral medicine cuts the risk of hospitalisation or death from COVID-19 by almost 90 per cent.

'We have procured 250,000 doses of this promising treatment on behalf of the whole UK and our independent medicines regulator, the MHRA, will now assess its safety, quality and effectiveness.

'If approved, this could be another significant weapon in our armoury to fight the virus alongside our vaccines and other treatments, including molnupiravir, which the UK was the first country in the world to approve this week.'

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Friday, November 05, 2021



UK approves Merck's antiviral COVID pill molnupiravir in world first

The UK's Medicines and Healthcare products Regulatory Agency (MHRA) on Thursday recommended the drug, molnupiravir, be used as soon as possible following a positive COVID-19 test and within five days of the onset of symptoms.

The pill was licensed for adults 18 and older who have at least one risk factor for developing severe disease, such as obesity or heart disease.

It is the first oral antiviral treatment for COVID-19 to get approved, with the green light coming ahead of potential US regulatory clearance.

US advisers will meet this month to vote on whether molnupiravir should be authorised.

Australia's Therapeutic Goods Administration has not yet approved the drug but the federal government announced last month it had ordered 300,000 courses.

The drug, to be branded Lagevrio in Britain, has been closely watched since data last month showed it could halve the chances of dying or being hospitalised for those most at risk of developing severe COVID-19 when given early in the illness.

Merck's COVID treatment drug, molnupiravir, has only passed the first hurdle towards approval in Australia but the federal government has bought 300,000 doses after some promising preliminary results.

"Today is a historic day for our country, as the UK is now the first country in the world to approve an antiviral that can be taken at home for COVID-19," said Britain's health secretary, Sajid Javid.

"We are working at pace across the government and with the NHS to set out plans to deploy molnupiravir to patients through a national study as soon as possible."

The British government and the country's National Health Service have not yet confirmed how the treatment will be deployed to patients.

Last month, Britain agreed to a deal with Merck to secure 480,000 courses of molnupiravir.

In a separate statement, Merck said it was expecting to produce 10 million courses of the treatment by the end of this year, with at least 20 million set to be manufactured in 2022.

Then antiviral pill could halve the chances of dying or being hospitalised from COVID-19, but experts warn vaccines are still necessary.

The company and its partner Ridgeback Biotherapeutic have requested clearance for the drug with regulators around the world to treat adults with mild-to-moderate COVID-19 who are at risk for severe disease or hospitalisation.

Merck's preliminary results last month have not yet been peer reviewed or published in a scientific journal.

The company also did not disclose details on molnupiravir's side effects, except to say that rates of those problems were similar between people who got the drug and those who received dummy pills.

The drug targets an enzyme the coronavirus uses to reproduce itself, inserting errors into its genetic code that slow its ability to spread and take over human cells.

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The 1.5m myth: alarming distance Covid can travel and stay in the air

As Lidia Morawska stirred awake, her resolve from the night before to act, to shake things up, escaped her momentarily.

Her plan? To marshal eminent scientists from around the globe to pressure one of the world’s most influential groups, the World Health Organisation, to admit that it was wrong. Deadly wrong.

It was late March last year and the virus that causes Covid-19, SARS-CoV-2, was roving across the world and deaths were rising.

Concerned colleagues in China and Italy had been calling Morawska – a physicist and distinguished professor in atmospheric and earth sciences at QUT and one of the world’s foremost authorities on airborne particles and their effects on health – pleading for her help. They couldn’t get authorities in those badly affected countries to listen to the science.

She knew, they knew, that a virus such as SARS-CoV-2 was airborne, capable of hanging in the air for hours and travelling significant distance. They’d done the studies, seen the evidence.

But WHO and national health authorities everywhere were caught in what Morawska, 68, calls “medical dogma”; the long-held belief that viral particles could not travel further than arm’s length. Their advice for such a coronavirus remained as it had for decades; keep a distance of about 1.5m from others, wash your hands and sanitise surfaces.

It infuriated Morawska. “A complete misconception,” she says. But now, her frustration had turned to desperation. That weekend in March, WHO issued a communique, disseminated on Twitter, headlined: “Fact Check: Covid-19 is NOT airborne.”

“Well, this was something,” says Morawska. “It wasn’t disbelief, because I knew the medical community had this view but it was that alarm bells were rung. If WHO was spreading this kind of misinformation; this is wrong, this will lead to more cases.”

That Sunday, she wrote a letter to the WHO. That evening, she contacted colleagues.

Come Wednesday, March 31, she hit send on an email, signed by 36 scientists in fields such as physics, virology, engineering and medicine, urging change in WHO’s thinking – and directives. The virus, they said, could drift and survive in the air, especially in poorly ventilated and crowded indoor spaces.

Within an hour, Morawska had a reply from leaders at WHO headquarters in Geneva, setting up a Zoom meeting a couple of days later.

It didn’t go well. “When you know a group is against you – that was the feeling,” says Morawska.

It would take more than three months of lobbying and writing and badgering and advocacy by Morawska and her colleagues before WHO changed its advice.

Morawska’s dogged work led her to be named by TIME magazine as one of the world’s 100 most influential people for 2021.

It’s an honour for all involved, she says, but clouded by the fact that the delay in WHO altering its advice, meant “we lost people. That’s the tragedy”. And there is still work to be done.

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Republicans Crush in Numerous Races Across America, Prove the Red Wave Is Here

It appears, in an ironic twist, President Joe Biden has succeeded in the goal he stated during his inaugural address in January to unify the country.

Unfortunately for him and the Democratic Party, the unity is in opposition to their radical agenda.

Everywhere up and down-ballot from New York and New Jersey to Virginia and Texas, the GOP made improbable gains.

Of course, at the very top of the red wave is the governor’s race in Virginia where Republican Glenn Youngkin upset former Democratic Virginia Gov. Terry McAuliffe.

Keep in mind Biden won the Old Dominion State over former President Donald Trump by 10 percent just a year ago.

Youngkin wasn’t the only Republican to win statewide in Virginia for the first time in over a decade

U.S. Marine veteran Winsome Sears took the lieutenant governor’s race, becoming the first African-American woman elected to statewide office in the commonwealth’s history.

Additionally, GOP candidate Jason Miyares, who is Hispanic, is currently in the lead in the attorney general’s contest.

Republicans are also on track to take back control of Virginia’s House of Delegates, where the Democrats held a 55 to 45 majority.

The news keeps getting worse for Dems in VA, where the correction of a reporting error appears to have flipped another House of Delegates seat to the GOP. Republicans now on track for 52R-48D, pending provisionals/recounts.

Moving north, the GOP also had an impressive night in deep-blue New Jersey, which Biden carried by nearly 16 points.

The race between incumbent Gov. Phil Murphy and Republican Jack Ciattarelli is, as of Wednesday afternoon, too close to call.

Murphy had been well ahead in the polls, so Ciattarelli surging into a Tuesday night lead shocked political poll watchers.

Still votes to be counted in NJ but it appears the GOP’s Jack Ciattarelli could flip Morris, Atlantic, Gloucester and Cumberland counties after Biden carried them last fall.

Still, looks like Murphy is in the driver’s seat for a victory

Meanwhile, the GOP picked up multiple seats in the state General Assembly and Senate with others, including Democratic Senate President Steve Sweeney’s race, too close to call, according to NJ.com.

In neighboring New York, Republicans won four contested city council races in Brooklyn, Queens and Staten Island with the potential of picking up a fifth, the New York Post reported.

One winner was Inna Vernikov, an unabashed Trump supporter, who trounced her Democratic opponent Steve Saperstein by nearly 30 points for an open seat in Brooklyn’s 48th Council District.

Former New York Assemblyman Dov Hikind tweeted on Monday ahead of the election, “For the first time in a century, a Republican has a good chance to win a seat for office in ultra liberal Brooklyn. Electing @InnaVForNYC would send a strong message to Democrats that their destructive reign in major American cities will not go unchallenged!”

Next door in Pennsylvania, The Philadelphia Tribune reported that Republicans are poised for a clean sweep in statewide judicial elections, including picking up a seat on the Keystone State’s Supreme Court.

You’ll recall that’s the same Democrat-controlled Supreme Court that kept rubber-stamping all the changes to Pennsylvania’s election laws and procedures Democratic Gov. Tom Wolf’s administration made during the 2020 election cycle, contrary to the state’s constitution, which vests that power in the legislature.

Republicans also received good news coming out of the Lone Star State, where John Lujan won his special election, flipping a state House seat located in San Antonio from blue to red.

Our story: Republican John Lujan wins special election runoff to flip Texas House seat in San Antonio

Biden carried the district by 14 points last November, The Texas Tribune reported.

Overall, it was a very bad night for Democrats, and at least part of the blame undoubtedly falls on Biden.

Americans, by a wide margin, are dissatisfied with the current direction of the country with seven in 10 respondents (71 percent), including nearly half of Democrats polled (48 percent), saying the U.S. is “off on the wrong track,” according to an NBC News poll released over the weekend.

Just 42 percent approve of Biden’s job performance and 54 percent disapprove.

Biden’s approval number is down 7 percentage points, and his disapproval is up 6 percentage points since August.

The change comes after the chaotic and deadly pullout in Afghanistan, rising inflation, slowing economic growth and disappointing September jobs numbers.

Gallup reported last week that the 46th president’s approval rating dropped from 56 percent in the first quarter of this year to 44.7 percent in the third quarter, an 11.3 percent drop — the largest registered by any president since World War II.

Based on Tuesday’s election results, Biden has succeeded in unifying the country in the belief that he is leading it in the wrong direction.

Short of a major course correction, Democrats better prepare to run smack into a mighty red wave in next year’s midterms.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Thursday, November 04, 2021


Immunity from Vaccines and Infection Lasts at Least Six Months

Immunity against covid from the vaccine and previous infections both lasts six months, according to a brief released by the Centers for Disease Control and Prevention (CDC) on Friday.

In the brief, the agency said that current data shows that individuals who are fully vaccinated and those who had a previous COVID-19 infection each have a low risk of contracting another COVID infection for six months.

“Available evidence shows that fully vaccinated individuals and those previously infected with SARS-CoV-2 each have a low risk of subsequent infection for at least 6 months,” the brief reads. “Data are presently insufficient to determine an antibody titer threshold that indicates when an individual is protected from infection. At this time, there is no FDA-authorized or approved test that providers or the public can use to reliably determine whether a person is protected from infection.”

The brief also claims that evidence indicates that “vaccination after infection significantly enhances protection and further reduces risk of reinfection.” The CDC currently recommends the COVID-19 vaccination for all eligible persons, including those who’ve previously had the virus.

“[T]here is a wide range in antibody titers in response to infection with SARS-CoV-2, completion of a primary vaccine series, especially with mRNA vaccines, typically leads to a more consistent, and higher-titer initial antibody response,” the brief reads. “[A]ntibody test results (particularly when not standardized nor quantitative) provide only a partial picture of an individual’s immune response. At this time there is no specific antibody test or antibody threshold that can determine an individual’s risk of subsequent infection.”

A separate study released by the CDC on Friday showed that the COVID-19 vaccine provides better protection against hospitalization than a previous infection with the virus.

“We now have additional evidence that reaffirms the importance of COVID-19 vaccines, even if you have had prior infection,” CDC Director Rochelle Walensky said in a statement on the study. “This study adds more to the body of knowledge demonstrating the protection of vaccines against severe disease from COVID-19.”

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Top Doctor Says New CDC Study on Natural Immunity Is 'Highly Flawed'

Last week the Centers for Disease Control published a study claiming vaccination for the coronvirus was superior to immunity obtained through natural infection.

Given the CDC's record of issuing "science" based on political motives and leanings, the study was met with skepticism.

Further, a number of other studies have shown natural immunity is far superior to vaccination in terms of protection against infection. The Brownstone Institute has a solid analysis of the CDC study compared to a recent Israeli study, which shows natural immunity offers better protection.

Concerning the Covid recovered, there are two key public health issues. 1. Would the Covid recovered benefit from also being vaccinated? 2. Should there be vaccine passports and mandates that require them to be vaccinated in order to work and participate in society?

The CDC study did not address the first question, while the Israeli study showed a small but not statistically significant benefit in reducing symptomatic Covid disease. Future studies will hopefully shed more light on this issue.

Based on the solid evidence from the Israeli study, the Covid recovered have stronger and longer-lasting immunity against Covid disease than the vaccinated.

Many of the Covid recovered were exposed to the virus as essential workers during the height of the pandemic before vaccines were available. They kept the rest of society afloat, processing food, delivering goods, unloading ships, picking up garbage, policing the streets, maintaining the electricity network, putting out fires, and caring for the old and sick, to name a few.

They are now being fired and excluded despite having stronger immunity than the vaccinated work-from-home administrators that are firing them.

Johns Hopkins Doctor Marty MaKary is calling the CDC study "highly flawed."

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New Vaccine Science Shows Mandates Are Unwise

New scientific findings in the prestigious Lancet Infectious Diseases journal blow a hole in the argument that workers need to get vaccinated to protect those around them. The findings prove the foolishness of forcing police and other public employees to get jabbed or lose their pay. And President Joe Biden should retract his order to the Occupational Safety and Health Administration to compel large employers to mandate vaccines.

The journal reported Thursday that COVID-19 vaccines have “minimal” impact on preventing transmission of the delta strain. Delta is the COVID strain currently causing over 99% of U.S. cases.

Vaccines protect the people getting the shots from serious illness, but they don’t stop the delta variant from spreading to others.

Don’t get me wrong. Americans should choose to get vaccinated. The key word is “choose.” Though shots are no guarantee against getting infected and spreading it to others, they provide significant protection (90% or more) against hospitalization and death. I’m triple jabbed.

Choosing not to get vaccinated is choosing to risk your own life. The health risk to others is minimal.

Most vaccines — against polio, smallpox, measles and other diseases — prevent infection and spread. But not COVID-19 vaccines. Now that the battle is against the delta variant, they’ve become disease-tamers rather than infection preventers.

Tell that to Mayor Bill de Blasio, who gave New York City employees until Monday to get at least one shot or be sent home without pay. As of Monday, 9,000 are on unpaid leave because they have refused the shots. Twenty FDNY companies were shuttered because many of New York’s bravest refuse the vaccine. Police Commissioner Dermot Shea claims the mandate will not further diminish the number of New York’s finest on the street. That remains to be seen.

Governors and mayors from Maine to Los Angeles are demanding that public employees, and even nurses and doctors, hailed just months ago as heroes, get vaxxed or go without a job.

Maine Gov. Janet Mills says, “just as vaccination defeated smallpox and vaccination defeated polio, vaccination is the way to defeat COVID-19.” Sorry, Governor, but you don’t know what you’re talking about.

Just as politicians don’t read the bills before voting on them, they don’t keep up with science but still want to tell the rest of us what to do.

The groundbreaking findings in Lancet show that fully vaccinated people who came down with COVID [i.e. "breakthrough infections] infected others in their household at the same rate (about 25%) as unvaccinated people did (about 23%). The vaccinated had just as much viral load in their upper respiratory tract, making them just as contagious. “Our findings show that vaccination alone is not enough to prevent people from being infected with the delta variant and spreading it,” study co-author Ajit Lalvani said.

The British researchers also found that vaccinated people were only somewhat less likely to contract the virus (25%) compared with the unvaccinated (38%). [Wrong. Those percentages reflect the SECONDARY attack rate only] That conflicts with Centers for Disease Control and Prevention data showing the vaccinated are far less likely to contract COVID.

One thing is for sure: The science is uncertain on this. So, government should not be using a heavy hand to impose mandates claiming to make workplaces safer.

Meanwhile, the White House is pressing large companies to mandate vaccinations and calling on OSHA to enforce that policy with hefty penalties. The Build Back Better bill increases the penalties tenfold to as much as $700,000 per incident for hazardous conditions, threatening bankruptcy for all but the largest enterprises. The Biden administration expects to publish the rules in the Federal Register in the coming days, affecting about two-thirds of the private sector workforce.

Yet the new science undercuts OSHA’s claim that unvaccinated people are a workplace hazard. So far, workplace mandates have been challenged at least 39 times in federal courts with little success, but the new scientific evidence may change that.

Lancet Infectious Diseases stressed the urgency of improving current vaccines or developing new ones to actually “protect against asymptomatic infections and onward transmission.”

Foolishly, the Biden administration and Democrats in Congress vilify the vaccine developer Moderna for making a profit and threaten to seize its patents. It’s possible COVID will continue morphing into new variants, requiring new vaccines from companies like Moderna.

When you’re fighting a war — in this case, against a killer disease — attacking your own ammunitions maker is no way to win it.

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Biden Agenda Suffers Another Loss as Senate GOP Kills Federal Election Takeover

Less than 24 hours after arriving back in the United States, President Biden's legislative agenda suffered another loss at the hands of Republicans in Congress on Wednesday.

The John Lewis Voting Rights Act, yet another Democrat attempt to hand the federal government control of America's elections, failed to secure the support necessary to overcome a Republican filibuster in the Senate.

Vice President Kamala Harris presided over the latest loss for the Biden-Harris legislative agenda that came out 50 to 49, short of the 60 vote threshold necessary to move the bill forward.

Jason Snead, executive director of the Honest Elections Project which opposed the John Lewis Voting Rights Act, explained in a thread on Twitter before Wednesday's vote how this bill was just another zombified version of the previously defeated For the People Act.

Even though Democrats were able to bring Republican Alaska Senator Lisa Murkowski over to their side ahead of the vote, other Senate Republicans held fast and prevented the bill from moving forward.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Wednesday, November 03, 2021


Vaccinated people are still highly likely to give covid to others

A new Lancet study about the transmission of Covid-19 among the vaccinated vs. unvaccinated is raising questions for some about vaccine mandates.

The study on “Community transmission and viral load kinetics” of the Delta variant in both the vaccinated and unvaccinated in the UK found the former were just as likely as the latter to spread Covid-19 among those in their household.

The vaccinated also had a similar viral load as the unvaccinated.

“Although vaccines remain highly effective at preventing severe disease and deaths from COVID-19, our findings suggest that vaccination is not sufficient to prevent transmission of the delta variant in household settings with prolonged exposures,” noted the paper, which studied 621 symptomatic participants over a year.

Significantly, the research found the vaccine was much more effective at reducing transmission of the alpha variant in a household, rather than the delta variant.

For some, the findings raise serious questions about vaccine mandates and lockdown efforts that governments around the world have pursued in an effort to contain the pandemic.

The researchers also noted booster shots and increasing the rate of vaccination among younger populations will help but the focus ought to remain on those most vulnerable.

“Increasing population immunity via booster programmes and vaccination of teenagers will help to increase the currently limited effect of vaccination on transmission, but our analysis suggests that direct protection of individuals at risk of severe outcomes, via vaccination and non-pharmacological interventions, will remain central to containing the burden of disease caused by the delta variant,” the researchers wrote.

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Greece Covid cases: Country records highest daily infections to date

After opening its borders during the summer tourism season, Greece has just recorded the highest daily increase of Covid-19 cases, since the start of the pandemic.

The European country reported 5400 cases on Monday, which pushes its daily average to 3900 new infections a day.

The country also recorded 52 deaths from Covid-19, which takes their pandemic death toll to 15,990 out of 747,595 cases.

Despite ballooning cases and rising deaths, a nationwide lockdown seems unlikely, reports local Athens-based newspaper, Kathimerini.

Development Minister Adonis Georgiadis said the government wasn’t looking at imposing a lockdown in winter, with the country shifting its Covid-recovery plan to focus on increasing vaccinations.

“We are now dealing with the pandemic of the unvaccinated,” he told local TV channel, Skai TV. “Our national right to lock people up has disappeared.”

Currently, 60.5 per cent of Greece’s population is fully-inoculated, with figures lagging behind the European average of 75 per cent.

Just four weeks ago Greece’s Health Miniser Thanos Plevris announced the removal of all indoor Covid-19 restrictions for fully vaccinated people. This meant business-as-usual activity was able to resume in restaurants, cafes, bars and nightclubs, with customers allowed to stand while drinking, play music and dance.

“A key prerequisite to regain our freedom is the increase in vaccination. We want to send the message that where the risk is lower, freedoms will reach the norm,” said Mr Plevris.

In order to encourage citizens to get the jab, unvaccinated public and private employees have been forced to pay for weekly tests in order to gain entry into their place of work and sports stadiums, museums, archaeological sites, cinemas and restaurants. The government has also mandated vaccines for healthcare workers.

The sudden uptick in cases is a dire sign for Greece’s already struggling economy. Just four years after the country emerged from a six-year depression between 2010 to 2016, Greece was plunged into another recession in 2020.

Writing for Vox EU, Professor of Economics, Athens University of Economics and Business and the former Greek Minister of Economy and Finance, George Alogoskoufis expects it will take years for Greece’s economy to recover.

“Greece appears to have experienced a very deep recession in 2020 and even under optimistic assumptions, a full recovery will take some time beyond 2021,” he wrote.

“In addition, the recession and the cost of the measures to mitigate it have already led to a further sharp rise of Greece’s already exorbitantly high public debt.”

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CDC Says Young Kids Can Receive COVID Vaccine

A whole new frontier has opened up in the battle over COVID-19 vaccines, and it’s one that is going to invoke a great deal of emotion and anger. That’s thanks to the latest recommendations from the CDC, which were released on Tuesday.

Vaccine advisors for the U.S. Centers for Disease Control and Prevention (CDC) voted Tuesday that children ages 5-11 should get COVID-19 vaccines.

The vote comes after a special federal advisory committee met to debate the issue. A final say on the matter is expected from CDC Director Dro. Rochelle Walensky.

Last week, the U.S. Food and Drug Administration (FDA) authorized emergency use for kid doses, which are about one-third of the dose given to adolescents and adults. The vaccine is already approved for emergency use in children 12-15 years old.

Tuesday’s move means that as many as 28 million more children could be eligible for vaccinations as soon as this week.

Of course, this also means that the federal government could hide behind CDC approval in mandating that all school-aged children be vaccinated to attend public school, which is the very issue that the anti-vax movement has been fighting for decades.

Despite what is sure to be a mighty pushback, the Biden administration is already full-steam ahead on the plan.

The Biden administration, awaiting a green light, has been assembling and shipping millions of COVID-19 shots for children.

“We are not waiting on the operations and logistics,” White House coronavirus coordinator Jeff Zients said Tuesday, assuring that the administration is “in great shape on supply.”

We can only imagine what school board meetings would begin to look like should vaccine mandates for children be considered.

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Professor of Medicine on Suing School Over Vaccine Mandate

Dr. Aaron Kheriaty reacted to the COVID-19 pandemic like many other medical experts. He worked long hours as the United States tried to grapple with the new disease. He had too many conversations with family members whose loved ones were dying from it.

But as time wore on, he started noticing a pattern in public health decisions that seemed to diverge from traditional medical ethics, including an insistence that people at little risk from COVID-19 get a vaccine.

Kheriaty is now on suspension from the University of California, Irvine, (UCI) and challenging the school’s COVID-19 vaccine mandate in court.

“I had to stand up and try to do something about it,” the professor of psychiatry and director of the UCI Health’s Medical Ethics Program said on The Epoch Times’ “American Thought Leaders.”

Kheriaty contracted COVID-19 in mid-2020. His infection was confirmed by two different tests from two independent labs. His five children and wife also contracted the disease. They all recovered, with none requiring hospital care.

“It was, for me, actually a very liberating experience afterward, because I didn’t have to worry about the illness anymore. I knew the science on natural immunity,” Kheriaty said.

Natural immunity refers to when people contract COVID-19 and recover. Dozens of studies have documented that these individuals enjoy strong immunity against CCP virus re-infection. Some of the studies suggest the immunity is superior to that provided by COVID-19 vaccines, particularly the Johnson & Johnson one.

“I knew that at that point, I was among the safest people to be around, I didn’t have to worry about transmitting the infection to my patients,” Kheriaty said.

He continued taking precautions, wearing personal protective equipment like masks as required at the hospital. But he was confident he didn’t pose a risk to others, which served as a relief.

That relief turned into disbelief when, around a year later, the University of California system, which includes UCI, imposed a COVID-19 vaccine mandate.

The mandate (pdf) included a natural immunity opt-out, but only temporarily. People who recovered from COVID-19 were told they would only be exempt from the mandate for up to 90 days after their diagnosis.

University officials cited the Food and Drug Administration (FDA), which alleges that the antibody tests it has authorized “are not validated to evaluate specific immunity or protection from SARS-CoV-2 infection.”

“For this reason, individuals who have been diagnosed with COVID-19 or had an antibody test are not permanently exempt from vaccination,” officials said.

The mandate violated rights outlined in the U.S. Constitution’s Fourteenth Amendment, including equal protection and substantive due process, Kheriaty’s lawsuit asserts.

“Plaintiff is naturally immune to SARS-CoV-2. Therefore, plaintiff is at least as equally situated as those who are fully vaccinated with a COVID-19 vaccine, yet defendants deny plaintiff equal treatment and seek to burden Plaintiff with an unnecessary violation of bodily integrity to which plaintiff does not consent in order to be allowed to continue to work at UCI,” it states.

The situation creates two classes, vaccinated and unvaccinated, when a more reasonable division would be those who are immune and those who are not, Kheriaty believes.

“What kind of discriminatory policies do we have in place that are excluding someone like me from the workplace when I’m 99.8 percent protected against reinfection whereas someone who got the Johnson & Johnson vaccine, by the company’s own data that they submitted to the FDA, is 67 percent protective against COVID infection?” he said.

Most mandates across the country don’t have alternatives for people who had COVID-19 and recovered.

Kheriaty proposes putting the burden of proof on people who want to opt out.

“Just have them go get the testing on their own time. You don’t have to administer the T-cell test or the antibody test. You don’t have to go dig up their old medical record establishing that they’ve already had COVID,” he said.

“Just ask them to bring that in and sign off on that as a kind of immunity passport.”

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Tuesday, November 02, 2021



Unvaccinated people are up to 32 times more likely to die if they catch Covid than the double-jabbed, ONS report finds

This is all very well if you believe official British statistics. It is now well known that Covid deaths have been heavily overstated in Britain. A man can die in a mororbike crash and still be counted as a Covid death if he has a cold or some such at the time. The statistics below sound to me like propaganda -- like the percentage of the vote that dictators get in an election

Unvaccinated people are up to 32 times more likely to die if they catch Covid than the double-vaccinated, official figures suggested today.

An Office for National Statistics (ONS) report found the mortality rate for deaths involving Covid in England among unjabbed adults was 849.7 per 100,000. For comparison, the rate stood at just 26.2 for fully vaccinated people and 105.3 for adults who had only had their first dose.

Death figures were for between January 2 to September 24 this year, which includes the brunt of the second wave when millions of adults weren't yet eligible for vaccines.

People were counted as being single- or double-vaccinated from 21 days after each dose because of the length of time taken for immunity to kick in and protect against the virus.

Experts today heralded the results as clear evidence that everyone should get the vaccine. But some warned that the figures may have 'overstated' the power of jabs.

In the report mortality rates were age-standardised, to account for the fact different age groups were vaccinated at separate times.

Older people who are most likely to die if they catch the virus were prioritised in the roll out, with the over-80s invited to get their first dose in December. But those in their early 20s had to wait until June to be called.

There was also a gap of 12 weeks between the first and second dose towards the beginning of the drive to ensure the maximum number of people could be jabbed in the shortest time possible. But in June this was cut to eight weeks.

A report by the UK Health Security Agency — which replaced the now-defunct Public Health England — published on Friday found being jabbed slashed the risk of someone infected with AY.4.2 developing symptoms by 81 per cent.

For comparison, two doses are thought to block around 83 per cent of all people falling ill with the ancestor strain.

The UKHSA said the preliminary results do 'not suggest a significant reduction in vaccine effectiveness for AY.4.2 compared to Delta' and admitted the slight drop may be down to chance.

Almost 24,000 cases of the strain have now been spotted in Britain. But the true count could be 10 times higher because laboratories are only sequencing a fraction of all confirmed samples.

Separate surveillance data shows the variant has now been found in all but a dozen parts of England and makes up one in ten new cases — with its proportion having doubled in the space of a month.

Despite statistics showing it's still outcompeting its ancestor, some experts are now questioning how much more transmissible than Delta the subtype really is. Scientists initially estimated the strain was around 10 to 15 per cent more infectious.

Figures show while cases of the mutant strain are continuing to increase, its curve is flattening off. It is increasing slower than its predecessor did at this point after it was first sequenced.

The ONS used figures from the Public Health Data Asset database, which contains people in England linked to the census in 2011 and GP records in 2019, to establish who had received the vaccine. It covers just under 80 per cent of the country's population.

The report also included data on deaths from all causes — such as heart disease and cancer, not just Covid.

It showed the un-vaccinated were still three times more likely to have died between January to December (2,187 per 100,000) than those who got two doses of the vaccine (783.6).

Commenting on the data John Roberts, from the Covid actuaries response group, said on Twitter: 'The difference in total mortality between the two groups (1,403.5) is more than the difference in Covid deaths (823.5).

'That's almost certainly due to the fact the demographic profile of the unvaccinated experiences higher mortality normally.

'We know that uptake has been lower in ethnic minority groups and more deprived areas, so in fact I would have been surprised if we didn't see this difference. So the 32 times might overstate the vaccine effect, but it is still going to be considerable.'

Chris Snowdon, head of lifestyle economics at the Institute for Economic Affairs, warned the statistics may have 'gilded the lily' slightly because of the time period used.

He tweeted: 'This is a dodgy statistic when very few people were fully vaccinated until March. The evidence is good without having to gild the lily like this.'

Almost 50million Britons — or 86.9 per cent of over-12s — have got at least one dose of the Covid vaccine, and 45.7million have received both doses.

The NHS started rolling out vaccines to over-80s, the vulnerable and health and social care workers in December.

It is now also offering them to 12 to 15-year-olds following a recommendation from No10's vaccine advisers back in September, although uptake has been sluggish.

And booster shots are being offered for the over-50s from six months after their second dose to top-up their immunity ahead of what is expected to be a very hard winter for the NHS.

The report builds on evidence that Covid vaccines slash the risk of hospitalisation and death among people who catch the virus, and its variants.

A report by the UK Health Security Agency — which replaced the now-defunct Public Health England — found last week that jabs work just as well against the more transmissible Delta offshoot as they do on its ancestor.

Scientists said the vaccines slashed the risk of someone infected with AY.4.2 of developing symptoms by 81 per cent.

For comparison, two doses are thought to block around 83 per cent of all people falling ill with the ancestor strain.

The UKHSA said the preliminary results do 'not suggest a significant reduction in vaccine effectiveness for AY.4.2 compared to Delta' and admitted the slight drop may be down to chance.

Almost 24,000 cases of the strain have now been spotted in Britain. But the true count could be 10 times higher because laboratories are only sequencing a fraction of all confirmed samples.

Separate surveillance data shows the variant has now been found in all but a dozen parts of England and makes up one in ten new cases — with its proportion having doubled in the space of a month.

Despite statistics showing it's still outcompeting its ancestor, some experts are now questioning how much more transmissible than Delta the subtype really is. Scientists initially estimated the strain was around 10 to 15 per cent more infectious.

Figures show while cases of the mutant strain are continuing to increase, its curve is flattening off. It is increasing slower than its predecessor did at this point after it was first sequenced.

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Virus vaccine trials had even gender split

Clinical trials of COVID-19 vaccines were largely gender balanced, although researchers have warned a failure to report on whether different side effects were experienced by men and women may limit future work in an emerging field.

A group of Australian researchers analysed more than 300 published papers on COVID-19 vaccines and found women and men were equally recruited and represented in randomised controlled trials. This is a departure from usual trends where male participants dominate medical research.

However, only a third of the randomised control trials reported efficacy data on a gender basis, and none reported whether any particular side effects of the vaccine were more common in men or women.

While historically medical trials would often exclusively use male participants, recent research has still been affected by an under-representation of women, said lead author Dr Amy Vassallo, from Sydney’s George Institute for Global Health.

Dr Vassallo said it was great to see researchers prioritise an equal gender split, but there was “a level of detail we’re missing out on”.

“We were all comforted when we knew getting AstraZeneca that we were expected to have a slightly worse reaction with the first dose, and Pfizer with the second dose, so after your vaccine if that happened it was normal and expected,” she said.

“But there were also possible sex and gender differences in responses to vaccines which we did not have knowledge about.”

While all available COVID-19 vaccines were found to be equally safe for men and women in trials, Dr Vassallo said better knowledge about side effects can be an effective tool in combating hesitancy.

Anecdotal reports of COVID-19 vaccine side effects in women, including menstrual changes, have since been investigated through survey data. A UK analysis published in September found the low prevalence of reports meant it was unlikely there was a link, although acknowledged the reporting method was not ideal

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Monday, November 01, 2021



Booster vaccination reduces risk of COVID hospital stint by 93 per cent

Getting a Pfizer booster jab five months after a second dose reduces a person’s risk of hospitalisation with COVID by 93 per cent, according to research published in The Lancet.

The study from the Clalit Research Institute in Tel Aviv and Harvard University in the US is the first nationwide analysis of booster jab effectiveness and involved 1.5 million Israelis.

Half of these people got a booster, while the other half had not yet received one. Israel was a pioneer in the distribution of vaccines at the start of 2021, getting a jab in the arm of half of its population by the end of February. But by the time a fourth wave hit the nation in summer, there was some waning of vaccine-induced immunity.

Data from the study show that a person’s risk from COVID in the week after getting a booster is much lower than someone who is only double-jabbed.

“Vaccine effectiveness... was estimated to be 93 per cent for admission to hospital, 92 per cent for severe disease, and 81 per cent for Covid-related death,” the researchers write in their paper.

The protection from the fresh inoculation was found to be unaltered by the recipient’s age, overall health or age. But while a booster did drastically reduce the threat of COVID relative to someone who does not get their booster, the absolute risk from COVID is still tiny for the double-jabbed.

For example, of the three-quarters of a million people who did get a booster, there were just 44 COVID deaths among the double-jabbed, compared to seven for the booster group. Only 29 people who got a booster went on to be admitted to hospital due to COVID.

Prof Ran Balicer, senior author of the study, from Clalit, said: “These results show convincingly that the third dose of the vaccine is highly effective against severe Covid-related outcomes one week after the third dose.”

Speaking about booster jabs, Boris Johnson called for all Britons to get their booster “as soon as you’re offered it”.

“It’s a very important message. I think people don’t quite realise that the first two jabs do start to wane.

“There is a waning effect on the first two, so people who are double vaccinated can experience a waning effect in their immunity. “How sad, how tragic it would be if people who had other complications other compromises in their health got seriously ill because they were overconfident about their level of immunity and didn’t get their booster when they needed it. “So please, please, please can everybody get their boosters.”

Israel will offer a third shot of the Pfizer vaccine to over 60s who received their second dose at least five months ago in order to fight the Delta variant.

A paper prepared by the Effectiveness Expert Panel shows that between three and six months, a double-vaccinated person who received the Oxford/AstraZeneca jab is still 85 per cent protected against hospitalisation compared to an unvaccinated individual. For death, the reduction in risk is 90 per cent.

Pfizer performed slightly better, with two doses giving 95 per cent protection against both death and hospitalisation.

“These results show convincingly that the third dose of the vaccine is highly effective against severe Covid-19-related outcomes in different age groups and population subgroups, one week after the third dose,” said Prof Ran Balicer, the senior author of the study.

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Here's what we know about COVID-19 vaccines for kids

American families who are eagerly awaiting the ability to vaccinate their young children against COVID-19 may finally get their wish in the coming weeks.

On Friday, October 29, the U.S. Food and Drug Administration authorized Pfizer-BioNTech shots for kids ages 5 to 11. The move comes just days after an advisory committee reviewed the safety and effectiveness of the low-dose vaccine and voted unanimously in favor of it. If the Centers for Disease Control and Prevention follows suit in the coming days, the 28 million children in this age group will be able to join their older siblings and parents in getting the jab.

Documents sent to the FDA and released by Pfizer on October 22 provide results from their clinical trial with children in this age bracket. The data show that the vaccine offers strong protection for this age group, with a 90.7 percent efficacy rate in preventing symptomatic disease even against the Delta variant now in circulation.

The devastation COVID-19 has wreaked on adults has largely obscured how much children have suffered, says Ofer Levy, director of the Precision Vaccines Program at Boston’s Children Hospital, who is a member of the FDA committee that voted on the Pfizer vaccine. According to the CDC, nearly 2 million kids 5 to 11 have contracted COVID-19 since the pandemic began, and more than 150 have died.

Had COVID-19 struck as many children as it has without touching a single adult, it would still be a serious public health emergency, Levy says. The question now is how quickly parents will move to vaccinate their young children after shots become available.

When parents were asked last month in a Kaiser Family Foundation survey whether they want their 5 to 11 year old immunized against the coronavirus, 34 percent said they would do it right away. Thirty-two percent want to wait and see, and 7 percent said they will if it’s required, such as by school mandates. Twenty-four percent say they are completely opposed.

“It’s understandable that at this stage parents have a lot of questions,” says Kelly Moore, president and CEO of the nonprofit Immunization Action Coalition, of the group of parents planning to hang back. “People will always be cautious when it comes to their children, and we have not had safety and side effect information for this group before this point,” she says.

Similar dynamics occurred with adults, she notes, but “once people saw how it was working, many were eager to get vaccinated.”

Why kids need vaccines

Given the mass mortality among older adults, it’s easy to lose sight of how children in this younger age group have been impacted by the disease.

In addition to mild or moderate illnesses, more than 5,000 children have developed the serious, full-body reaction to the coronavirus known as Multisystem Inflammatory Syndrome in Children (MIS-C), the vast majority under age 11. The syndrome can cause fever, vomiting, and diarrhea and may lead to heart dysfunction, kidney injury, and, in rare cases, death.

“When you compare COVID’s effects on children to influenza and other diseases that affect them, COVID is much more devastating,” Moore says.

Of course, children suffer even when others develop the disease. Some 140,000 children have lost a primary or secondary caregiver from COVID-19 to date. And the numerous school shut downs and curtailing of social activities have had such a profound psychological effect that the American Academy of Pediatrics and other medical groups have declared children’s mental health to be in a national state of emergency.

What’s more, protecting children with the shots adds to the defenses for all members of their family, especially those younger than 5 who would still not yet be eligible, or any adults at risk of severe disease.

Moore has a friend whose husband is on immunosuppressing drugs to protect his kidney transplant. “Their 8-year-old daughter can’t even go into an ice-cream store because her father is vulnerable if she were to catch and transmit COVID,” she says.

A recent Swedish study confirmed the value of this ring of protection: Families where one member is immunized have up to a 61 percent lower risk that others in the home will get COVID-19, while three or four immunized members gives more than a 90 percent reduction.

Inoculating children in an effort to protect others already happens in the U.S., Levy says. “Some say it’s not ethical to vaccinate kids for a disease that doesn’t affect them as much,” he says, but children are currently immunized against rubella when the main risk is to pregnant mothers, he points out.

A smaller dose

Tens of thousands of adults were tested in Pfizer-BioNTech’s original clinical trials, and with 105,000 Americans over age 12 having completed the two-dose series, the FDA already has extensive information on the effectiveness of the shots. To test the vaccine for children 5 to 11, a different type of trial was conducted, largely focused on safety and dosage.

In the first phase of the trial, Pfizer gave a small group of children either the same 30 microgram dose used for those 12 and older, or they administered 20 or 10 microgram doses. This is a process known as a dose de-escalation trial, says Onyema Ogbuagu, an infectious diseases specialist at Yale Medicine and a principal investigator of the Pfizer trials.

“You want to find the dose that gives a strong immune response while trying to limit adverse events,” he says. The two-dose regimen of 10 micrograms each eventually won out. Pfizer is presenting the test results from some 2,268 participants to the FDA.

The FDA’s Vaccines and Related Biological Products Advisory Committee will comb through every bit of Pfizer’s data before deciding whether to recommend its authorization for 5 to 11s. Pfizer is also currently studying even smaller doses for children between 2 and 5 years old and for those between 6 months and less than 2 years. And more good news for parents of young children: Moderna announced on October 25 that its clinical trial in 6 to 11 year olds also produced a robust immune response.

Side effects seen in the Pfizer trial were similar to those for older children, including short-term injection site pain, fatigue, headache, and chills. There were no serious adverse events linked to the vaccine. “You can never say never in medicine, but we feel pretty confident that nothing untoward is expected when even more children get the vaccines,” Ogbuagu says.

Rare events that happen in 1-in-10,000 or 1-in-100,000 people will not emerge until that many children have been vaccinated. The rare cases of the heart inflammation known as myocarditis, which has primarily impacted male adolescents and young men after their mRNA vaccine series, is estimated to occur in roughly 1 in 26,000 males, and nearly all have since recovered.

Addressing parents’ concerns

When weighing any potential risks, parents must compare a vaccine with the disease it aims to protect their child against, Moore says. Even mild cases of COVID-19 can make children feel awful and keep them from attending school. Plus, an unknown number of children continue to suffer for months after their acute illness, a condition that’s come to be known as long COVID.

Among parents who worry, some are concerned about stimulating their child’s immune system with a vaccine, Ogbuagu says, but he counters that “the stimulation it gets when a person gets COVID is much more intense.”

Other resisters focus on the vaccine’s delivery system—the mRNA that instructs the body to create spike proteins for the immune system’s response. But vaccines routinely given to children for other diseases use many different technologies and most parents haven’t much cared, says Robert Jacobson, medical director of the Primary Care Immunization Program at the Mayo Clinic in Rochester, Minnesota.

For example, he says, the measles, mumps, and rubella (MMR) jabs and the chicken pox shots use a weakened form of a live virus. The vaccine for diphtheria employs an altered form of the bacteria. And hepatitis B’s vaccine involves tricking yeast through recombinant technology to produce a protein they don’t naturally make.

What’s more, Ogbuagu says, RNA-based viruses like influenza or respiratory syncytial virus (RSV) routinely infect kids, so it’s not as if their bodies haven’t seen the structure before. “If people knew the host of RNA viruses that enter their child’s cells all the time, they would worry less about the vaccine,” he says.

Pfizer-BioNTech’s shots are already proving valuable for children ages 12 to 17. Some 11 million Americans in this age group, or 57 percent of the total, have gotten at least one shot, while 47 percent are fully vaccinated, according to the AAP. The vaccines have been 93 percent effective in protecting kids this age from going to the hospital, the CDC announced last week.

If the CDC ultimately authorizes the vaccine for kids 5 to 11, Levy wants the shots to be mandated for school, as others currently are. In a recent medical journal editorial, he writes that decreasing virus circulation in children may be our best hope for controlling the spread of COVID-19.

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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