Two years later, coronavirus evolution still surprises experts. Here’s why

Scientists and physicians continue to be amazed by how quickly the virus evolves, what it does to the human body, and how it moves through species.

Raul Andino knows his pathogens. For more than 30 years the University of California, San Francisco researcher has studied RNA viruses, a group that includes the virus that causes COVID-19. And yet he never imagined he’d witness a pandemic of this scale in his lifetime.

“The magnitude of it and the implications of it are still hard to comprehend,” Andino says.

Although experts in his field suspected a pandemic would occur, “it’s hard to know when,” he says. “It’s similar to an earthquake—you know the earthquake will happen, but normally you don’t think about it.”

On March 11, 2020—exactly two years ago—the World Health Organization declared COVID-19 to be a pandemic. The disease has since infected nearly 500 million people in almost 200 countries and killed more than six million people worldwide, and it’s not over yet.

Along the way, this coronavirus has presented scientists with a bevy of surprises: Many experts are still amazed by how quickly the virus evolves, what it does to the human body, and how it moves in and out of other species.

The original SARS-CoV-2 virus rapidly evolved into a string of variants that have hindered a return to pre-pandemic normalcy. Even with the virus’s genetic blueprint in hand and the ability to decode the genomes of new variants within hours, virologists and healthcare professionals struggle to predict how its mutations will alter the virus’s transmissibility and severity.

Millions of people are grappling with symptoms that linger for weeks to several months after they’d been diagnosed with an infection. Scientists are racing to understand the biology of this new and perplexing syndrome called long COVID.

Two years in, there’s still a lot we don’t know about SARS-CoV-2, says David Wohl, an infectious disease specialist at the University of North Carolina. Here’s what scientists have uncovered so far—and the mysteries that continue to tantalize and frustrate coronavirus experts.

Worst-case scenario

Experts had been warning of some kind of looming pandemic for decades. As humans expand settlements into wild areas, they raise the odds of a new pathogen jumping from an animal to a person, giving rise to a deadly zoonotic disease. A study published in Nature showed that emerging infectious diseases originating in wildlife had increased significantly between 1940 and 2004.

But most experts were worried about influenza viruses and would not necessarily have expected a coronavirus to cause such havoc.

That changed with the 2002-04 Severe Acute Respiratory Syndrome (SARS) outbreak, which infected more than 8,000 people in 29 countries and left 774 dead. Then the 2012 Middle East Respiratory Syndrome (MERS) outbreak infected more than 2,000 people in 37 countries; that virus has so far killed nearly 900.

Still, people weren’t paying as much attention to coronaviruses compared to the “really bad guys” like influenza, HIV, dengue viruses, Andino says.

Then SARS-CoV-2 arrived with a bang. It was spreading faster than previous coronaviruses, and one reason, scientists suspect, is its ability to move efficiently from one cell to the next. SARS-CoV-2 is also harder to contain because it causes so many asymptomatic cases, people who can then unknowingly spread the virus. “In a way, SARS-CoV-2 has found a way in which it can [rapidly] spread and also cause disease,” Andino says. “It’s the worst-case scenario playing out.”

March of the variants

Adding to the oddities, the SARS-CoV-2 virus acquired genetic mutations much more rapidly than expected.

Coronaviruses usually mutate at lower rates than other RNA viruses, like influenza and HIV. Both SARS-CoV and SARS-CoV-2 accumulate approximately two mutations each month; half to one sixth the rate seen in influenza viruses. That’s because coronaviruses have proofreading proteins that correct errors introduced into the virus’ genetic material as it replicates.

“That’s why we thought [SARS-CoV-2] would not evolve very fast,” says Ravindra Gupta, a clinical microbiologist at the University of Cambridge.

But the virus quickly proved Gupta and his colleagues wrong. The emergence of Alpha—the first variant of concern identified in the United Kingdom in November 2020—stunned scientists. It had 23 mutations that set it apart from the original SARS-CoV-2 strain, eight of which were in the spike protein, which is essential for anchoring to human cells and infecting them.

“It became clear that the virus could make these [surprising] evolutionary leaps,” says Stephen Goldstein, an evolutionary virologist at the University of Utah. With this set of mutations, Alpha was 50 percent more transmissible than the original virus.

The next version, Beta, was first identified in South Africa and was reported as a variant of concern just a month later. It carried eight mutations on the viral spike, some of which helped the virus escape the body’s immune defenses. And when the Gamma variant emerged in January 2021, it had 21 mutations, 10 of which were in the spike protein. Some of these mutations made Gamma highly transmissible and enabled it to reinfect patients who previously had COVID-19.

“It’s surprising to see these variants make pretty significant leaps in transmissibility,” Goldstein says. “I just don’t think we’ve observed a virus do that before, but of course, we have not actually observed any pandemics previously with the amount of genetic sequencing capacity we have now.”

Then came Delta, one of the most dangerous and contagious variants. It was first identified in India and designated a variant of concern in May 2021. By late 2021 this variant dominated in almost every country. Its unique constellation of mutations—13 overall and seven in the spike—made Delta twice as infectious as the original SARS-CoV-2 strain, led to longer lasting infections, and produced 1,000 times more virus in the bodies of infected people.

"It [SARS-CoV-2]’s ability to come up with new solutions and ways to adapt and spread with such ease—it’s incredibly surprising,” Andino says.

However, Omicron, which is two to four times more contagious than Delta, rapidly replaced that variant in many parts of the world. First identified in November 2021, it carries an unusually high number of mutations—more than 50 overall and at least 30 in the spike—some of which help it evade antibodies better than all the earlier virus versions.

“These huge jumps [in mutations] make the pandemic far less predictable,” says Francois Balloux, a computational biologist at the University College London Genetics Institute in the United Kingdom.

Chronic infections

One of the most compelling explanations for the huge leaps in the number of mutations is that that the SARS-CoV-2 virus was able to evolve for long periods of time in the bodies of immunocompromised people.

During the past year, scientists have identified cancer patients and people with advanced HIV disease who were unable to get rid of their COVID-19 infection for months to nearly a year. Their suppressed immune systems enabled the virus to persist, replicate, and mutate for months.

Gupta identified one such mutation (also seen in the Alpha variant) in a sample from a cancer patient who remained infected for 101 days. In an advanced HIV patient in South Africa who was infected for six months, scientists recorded a multitude of mutations that helped the virus escape the body’s immune defenses.

“That the virus is changing its biology this quickly in its evolutionary history is a huge find,” Gupta says. Other viruses like influenza and norovirus also undergo mutation in immunocompromised individuals, but “it is very rare,” Gupta says, and they “infect a narrow range of cells.”

By contrast, SARS-CoV-2 has proven capable of infecting many different areas of the body—creating yet more baffling effects for scientists to untangle.

Not just a respiratory virus

Early in the pandemic medical professionals noticed that the virus wasn’t just causing pneumonia-like illness. Some hospitalized patients also presented heart damage, blood clots, neurologic complications, and kidney and liver defects. Mounting studies within the first few months suggested one reason why.

SARS-CoV-2 uses proteins called ACE2 receptors on the surface of human cells to infect them. But because ACE2 is present in many organs and tissues, the virus was infecting more parts of the body than just the respiratory tract. There were also a few reports of the virus, or parts of it, in blood vessel cells, kidney cells, and small quantities in brain cells.

“I’ve studied a lot of pandemics, and in almost all of them, you look at the brain, you’ll find the virus there,” says Avindra Nath, a neuroimmunologist at the National Institutes of Health. For instance, brain autopsy tissues from 41 hospitalized and dead COVID-19 patients revealed low levels of the virus. But there were also clear signs of damage, including dead neurons and mangled blood vessels.

“That’s the biggest surprise,” Nath says.

It’s likely that the virus triggers the body’s immune system to go into a hyperactive mode called a cytokine storm, which causes inflammation and injury to different organs and tissues. An abnormal immune response can persist even after infection, resulting in lingering symptoms including chronic fatigue, heart palpitations, and brain fog.

“But there are virus reservoirs that can cause chronic inflammation,” says Sonia Villapol, a neuroscientist at the Houston Methodist Research Institute. A recent study that’s not yet been peer-reviewed showed that SARS-CoV-2 genetic material could persist for up to 230 days in the body and brains of COVID-19 patients, even in those who harbored only mild or asymptomatic infections.

Susan Levine is an infectious-disease doctor in New York who specializes in the treatment and diagnosis of chronic fatigue syndrome, which has parallels with long COVID. She now sees 200 patients every week, compared to 60 in pre-pandemic times. Unlike CFS, long COVID “hits you like a ton of bricks,” Levine says. “It’s like a tornado inside your body where you’re going from working 60 hours a week down to being in the bed all day within a week of getting the infection. The action is so compressed.”

https://www.nationalgeographic.com/science/article/two-years-into-the-pandemic-covid-19-still-surprises-experts

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COVID-19 Vaccines May Be Enhancing Disease: Malone

COVID-19 vaccines may be causing enhanced disease because they target an old version of the coronavirus, Dr. Robert Malone says.

“The data are showing that vaccination can actually increase the risk of being infected with the Omicron version of this virus,” Malone told The Epoch Times in a recent interview.

Malone was referring to how in some areas, including Scotland and New Zealand, patients hospitalized with COVID-19 are more likely to have received a COVID-19 vaccine than not.

A recent study, meanwhile, found that one dose of a vaccine boosted protection for people who recovered from COVID-19 but two or three doses seemed to lower protection; the authors said they weren’t sure why this was the case. Another study found higher protection among naturally immune who weren’t vaccinated versus those who were.

Vaccine-associated enhanced diseases (VAED) were identified (pdf) as an “important potential risk” of the COVID-19 vaccines by U.S. drug regulators, as was a similar event known as enhanced respiratory disease following COVID-19 vaccination. Some adverse events recorded following COVID-19 vaccination “could indicate” VAED (pdf), according to a Centers for Disease Control and Prevention (CDC) team.

VAED refers to disease “resulting from infection in individuals primed with non-protective immune responses against the respective wild-type viruses,” researchers said last year as they set a case definition for the term. “Given that these enhanced responses are triggered by failed attempts to control the infecting virus, VAED typically presents with symptoms related to the target organ of the infection pathogen,” they added.

“That’s what the data has been showing now for a few months,” Malone, who helped invent the messenger RNA technology that two of the three COVID-19 vaccines cleared for use in the United States is built on, told The Epoch Times.

In a Pfizer document (pdf) released this month, the vaccine manufacturer said there were a potential 138 cases with 317 relevant events of VAED reported from December 2020 to February 2021. Of the 138 cases, 71 were medically significant, 16 required hospitalization, 13 were life-threatening, and there were 38 deaths.

The most frequently reported event out of the 317 potentially relevant events was drug ineffectiveness (135). Other events included COVID-19 pneumonia, diarrhea, respiratory failure, and seizure.

“VAED may present as severe or unusual clinical manifestations of COVID-19,” Pfizer concluded, adding that, “based on the current evidence, VAED/VAERD remains a theoretical risk for the vaccine” and that they will continue to monitor the syndrome.

Pfizer, Moderna, and Johnson & Johnson didn’t respond to requests for comment.

A CDC spokesperson said that the agency, along with the Food and Drug Administration (FDA), are monitoring vaccine safety through surveillance systems such as the Vaccine Adverse Event Reporting System and v-safe.

Monitoring to date “has not established a causal relationship between COVID-19 vaccination and vaccine-associated enhanced disease,” the spokesperson told The Epoch Times in an email.

The CDC says the vaccines are largely safe and effective but also encourages people who experience side effects after getting one of them to report the issues to one of the systems.

The FDA, meanwhile, has not at this time identified an association between enhanced respiratory disease with the three vaccines the agency has cleared, a spokesperson told The Epoch Times via email.

https://www.theepochtimes.com/covid-19-vaccines-may-be-enhancing-disease-malone_4327001.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Victims vs. Vectors? The Ethics of Giving COVID-19 Vaccines to Children

Alma Golden

Fifty years ago, I began medical school. Through this half-century, I have provided, prescribed, promoted, and supported vaccine use. As a physician in retirement, I am fully vaccinated and boosted for COVID-19, as are my grown sons and three of my young adult grandchildren.

Vaccine development has a proud history that has prevented millions of children and adults from becoming the victims of infectious diseases. But are children’s COVID-19 vaccines now being used to prevent serious illness in children or as a vector control mechanism to protect adults?

I rejoiced as the Hemophilus influenza type b vaccine saved thousands of infants and children from death or serious disease caused by meningitis and sepsis. I followed the public health science that tracked data and research on the risks, costs, and benefits of vaccines to prevent chickenpox, rotavirus, and many other—now preventable—diseases.

The Hemophilus influenza type b, or Hib, vaccine was a classic study in recognizing and responding to a health threat in children. Data were collected on the frequency of hospitalizations, permanent disabilities, sepsis, meningitis, and death associated with Hib infection in infants and toddlers. Risk, benefit, and cost analyses were developed. Immunized children were monitored for efficacy and adverse effects, both short-term and long-term. The success of that vaccine is a win for nations as well as families.

The ethics of child vaccines should reflect the high standards like this, which have been used since the enactment of the National Childhood Vaccine Injury Act in 1986.

I know this well, as I practiced pediatrics through the turbulent era of rare but serious side effects associated with the pertussis vaccine, which a National Institutes of Health study concluded caused severe reactions in children such as seizures, hypotonic-hyporesponsive episodes, high fevers, and persistent crying.

This led to the passage of the National Childhood Vaccine Injury Act of 1986 Vaccine Injury Compensation Program, which helps promote development of safe vaccines, addressed compensation for injured vaccine recipients, and simultaneously mandated tracking of vaccine distribution and adverse effects, leading to better vaccine programs and fewer preventable infectious diseases.

Twenty-four months of the SARS-CoV-2 pandemic has demonstrated that few healthy children infected with the virus become victims of severe illness and that those most likely to need intensive care already have previously diagnosed significant health conditions. Most children and youth experience a relatively short duration of illness with low rates of hospitalizations and few deaths. Children are a magnificently resilient group. They appear to develop robust natural immunity.

Although children can be asymptomatic spreaders, some studies indicate that transmission rates between children and within families are lower than between adults. School environments, with some precautions and good ventilation, are surprisingly safe places.

Based on how rapidly the SARS-CoV-2 virus mutates, it may be difficult to develop effective vaccines to keep pace with new mutations, such as the omicron variant. It is possible that youth have been blessed with the capacity to respond successfully, and much more rapidly, to these variants than the scientists who are manufacturing the vaccines.

Considering the above, what is the ethical framework for promoting widespread or mandated pediatric COVID-19 vaccination?

Recognizing that children make up a minuscule percentage of severe COVID-19 cases, why are so many health, education, pharmaceutical, and political leaders vigorously promoting pediatric vaccination? Where are the data-based risk-cost-benefit analyses to support their recommendations?

Local and systemic vaccine reactions occur in 30% to 60% of children 5 to 11 years old, according to the Centers for Disease Control and Prevention. Myocarditis, or inflammation of the heart, is rare in that age group but increases in teen and early adult years, especially for males, as noted in multiple countries. Only short-term observations inform our understanding of the vaccine in children and youth. Long-term efficacy and side effects need to be monitored.

In the setting of a highly infectious, highly prevalent virus that appears to be approaching an endemic state, much like colds or the flu, are children to assume the ethical burden of vaccination to protect the larger society when the resulting benefit to them may be minimal and the potential long-term risks and benefits are not fully understood?

If we are concerned that children would serve as the distributors of disease, much as a mosquito is for malaria, does that reduce the obligation of researchers, clinicians, and public health experts to analyze—both medically and ethically—the full spectrum of risks, benefits, and potential impacts of this vaccine on children? Are we fulfilling the medical, regulatory, and ethical standards that have developed since the 1986 National Childhood Vaccine Injury Program?

Children with chronic or immunocompromised conditions and/or who are living with close family members with such conditions should be vaccinated, but one must ask whether the promotion of universal child vaccination for COVID-19 is driven by the evidence-based risk of severe disease, death, or disability in children, or by fear and expediency to benefit adults.

In another 50 years, I wonder if historians will observe that we treated children as disease vectors rather than potential victims of a viral illness.

https://www.dailysignal.com/2022/02/28/victims-vs-vectors-the-ethics-of-giving-covid-19-vaccines-to-children

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Even Mild Cases of COVID-19 Can Lead to Brain Changes

Mild COVID-19 cases were linked to changes in the brain, in a newly published study.

Approximately 785 people underwent a brain scan and about half later tested positive for COVID-19. All the participants got a second brain scan, including those who had survived the disease.

Researchers from the Wellcome Centre for Integrative Neuroimaging at the University of Oxford analyzed the scans and found the participants infected with COVID-19 had a reduction in the thickness of gray matter—which helps humans perform various functions such as making decisions—and other negative outcomes.

“Despite the infection being mild for 96% of our participants, we saw a greater loss of grey matter volume, and greater tissue damage in the infected participants, on average 4.5 months after infection,” professor Gwenaëlle Douaud, the study’s lead author, said in a statement.

“They also showed greater decline in their mental abilities to perform complex tasks, and this mental worsening was partly related to these brain abnormalities. All these negative effects were more marked at older ages.”

The paper was published in Nature following peer review.

The scans were taken from the UK Biobank, a large-scale medical database that contains information on approximately 500,000 UK residents.

Those whose scans were analyzed were aged 51 to 81. The reason the study did not include younger people is that all participants in the scanning were 40 or older, Douaud told The Epoch Times in an email.

The scans were taken on average 38 months apart.

Researchers said the two cohorts—people who ended up getting infected and people who did not—were similar in terms of age, sex, and many risk factors.

Participants also engaged in cognitive tests, and the infected group was more likely to experience cognitive decline by the time of the second test.

The brain changes ranged from 0.2 to 2 percent additional change in the infected group.

https://www.theepochtimes.com/even-mild-cases-of-covid-19-can-lead-to-brain-changes-study_4323882.html ?

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Researchers discover drug-resistant Covid in Australian patients

One of the main medicines used to combat severe cases of Covid-19 is causing the virus to mutate and there is a risk it could spread in the community.

If this happens, elderly and immunocompromised patients can’t be treated with the drug Sotrovimab.

Sydney University researcher Dr Rebecca Rockett studied 100 Covid patients in health care facilities in the Western Sydney Local Health District in New South Wales during the Delta outbreak between August and November 2021.

For four of the patients given the drug, the virus in their body mutated within six to 13 days and the treatment was no longer effective at containing the infection.

Samples of the mutated virus taken from these patients were able to be grown in a laboratory dish and this proved the new version of the virus was capable of spreading to others.

“The worrying thing is the fact that the virus was still viable and persisting in these patients after they develop the resistance,” Dr Rockett said.

“What we don’t want to see is that someone in the community develops resistance and they can pass that resistance to other people and that makes the drug ineffective, not just for that individual but for who they transmit the virus to,” she said.

Many of the patients in the study were severely immunocompromised and Dr Rockett said one theory about the emergence of the Delta and Omicron variants of the virus was that they developed in such people.

“There are definitely cases in the literature where these patients with really immunocompromised conditions are given a lot of different therapies and could develop a number of mutations that can make the virus less more likely to evade current vaccines and treatment strategies,” she said.

This is a key reason this population of patients should be kept under surveillance, she said.

To keep control of the virus, doctors must undertake active surveillance of severely ill patients and identify treatment-resistant mutations earlier so they can be contained, she said.

The research team has not conducted experiments to determine whether current Covid-19 vaccines could combat the mutated virus that developed in these patients.

Sotrovimab is one of three key Covid-19 treatments called monoclonal antibodies that doctors were using to stop patients from becoming seriously ill.

These types of treatments are laboratory-made proteins that mimic the immune system’s ability to fight off viruses.

In January, the US FDA revealed that two of these treatments no longer worked against Omicron leaving Sotrovimab as the only weapon in the arsenal.

In another worrying development last month a Colombia University study that is yet to be peer reviewed found the cousin of Omicron – BA. 2 – had developed resistance to Sotrovimab.

This leaves recently approved treatments paxlovid, molnupiravir which are in short supply as the mainstay of treatment.

https://www.couriermail.com.au/news/national/researchers-discover-drugresistant-covid-in-aussie-patients/news-story/2ab9993ba83490316810b59d307864b0

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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The Alarming Trends in COVID Vaccine Side Effects

In mid-February 2022, the U.K. started rolling out the COVID jab for children aged 5 to 11. In the U.S., the shot has been recommended for this age group since October 2021.

The question raised in a Nick De Bois interview with Jamie Jenkins, former head of health and labor market analysis at the British Office for National Statistics (above), is ‘Why bother injecting kids this young?’ The risk COVID-19 presents to children is minuscule.

What’s more, the British Joint Committee on Vaccination and Immunization (JCVI) estimates that by the end of January 2022, 85% of children aged 5 to 11 already had natural immunity. Add to that the fact that the prevailing variant, Omicron, is far milder than previous strains, causing only mild cold symptoms in most people, including children.

Together, these three facts ought to make it clear that children don’t need this jab. A cost-benefit analysis by Stephanie Seneff, Ph.D., and researcher Kathy Dopp, also shows the COVID jab actually increases children’s risk of dying from COVID infection. Children under 18 are also 51 times more likely to die from the jab than they are to die from COVID if not vaccinated.

Four Million Doses Required to Prevent a Single ICU Admission
An astounding statistic Jenkins does bring up is that 4 million doses must be administered to children, 5 to 11 years of age, to prevent a single ICU admission in this age group. Assuming two doses per child, that means 2 million children must take their chances with serious and potentially lifelong side effects to prevent a single child from requiring intensive care due to COVID-19. How is this justified? As explained in Jenkins’ website:

“JCVI has said that vaccination of children aged 5 to 11 years who are not in a clinical risk group would prevent a relatively small number of hospitalizations or intensive care admissions. For a variant like Omicron, it would take around four million vaccine doses to two million children to prevent one admission to ICU.

For less severe illnesses, 58,000 child vaccinations would prevent one-child hospitalization. Children admitted recently to hospital with COVID had an average length of stay of 1-2 days. The Omicron wave saw no more children in hospital than before Omicron hit the UK.”

Pfizer Backs Off Shots for Children Under 5

While vaccine makers and health agencies have been pushing forward with COVID jabs for babies as young as 6 months, parents with children under 5 can, for now, draw a sigh of relief, as plans to roll out shots for the under-5 age group have been suspended, at least temporarily.

February 11, 2022, Pfizer withdrew its U.S. Emergency Use Authorization (EUA) application for children under 5. According to the U.S. Food and Drug Administration and Pfizer, they want to collect more data on the effects of a third dose, as two doses did not produce expected immunity in 2- to 5-year-olds.

Three days later, former FDA Commissioner and current Pfizer board member Scott Gottlieb told CNBC the EUA application was pulled because COVID cases are so low among young children that the shot couldn’t be shown to provide much of a benefit.

Considering you have to give the jab to some 2 million children to prevent a single ICU stay, it’s no wonder they can’t show effectiveness in studies that have just a few thousand children. Pfizer’s youth trial on 5- to 11-year-olds had just 2,268 participants, and only two-thirds of those received the real COVID jab.

However, the OpenVAERS team suspects there may be something far more problematic behind Pfizer’s withdrawal. In a February 21, 2022, email notice to subscribers, OpenVAERS stated:

“None of these explanations suffice because all of that information was known prior to Pfizer submitting this EUA to the FDA on February 1 [2022]. It makes one wonder whether adverse events in the treatment group might be the factor that neither Pfizer nor the FDA want to talk about?

So, we decided to look at reports of injury associated with COVID-19 vaccines in children 17 and younger. Remember, these shots have only been on the market for a short while and only children 5 to 17 are eligible. We created a separate page called Child Reports that will update automatically as new reports come in.

We were shocked by what we found — 34,223 VAERS reports in the U.S. in this age range, including infants harmed through transmission from the mother via breast milk, lots of reports of kids receiving shots who were too young (either the parents lied about their age or the doctor/pharmacy made a mistake with screening or dosing), and heartbreaking reports of myocarditis and death.”

Shocking Data From Israel Show Extent of Side Effects

While health agencies and mainstream media still insist that side effects from the COVID jab are “rare,” real-world data show a different story. An English translation of the report can be downloaded from Galileo Is Back on Substack. As noted in the report:

“On December 20, 2020, a vaccination program was launched in Israel using Pfizer’s vaccine for COVID-19. By the end of March 2021, more than half of the population had been vaccinated with two vaccine doses.

The decrease in immunity over time and emergence of new variants led to a renewed increase in morbidity in Israel in the summer of 2021. By the end of July 2021, a third shot of the vaccine (booster shot) was authorized for everyone who had received two shots and at least five months had passed from the second shot.

From data collection by medical teams or self-reporting by the public of side-effects in temporal proximity (passive monitoring), it appears that there is underreporting; therefore, it is important to identify side-effects in temporal proximity to vaccination with the booster in an active manner via a dedicated survey.

General goals: To determine the frequency of side-effects which appeared within 21-30 days from vaccination with the third Pfizer shot (booster) against COVID-19 among citizens above 18 years of age.

Specific goals: Examine the prevalence of side-effects in temporal proximity to the third shot grouped according to age and gender. Examine the time of onset relative to administration of the vaccine and the duration thereof, and to compare it with the side-effects of previous vaccines.”

In all, 2,894 people were contacted and 2,068 agreed to be interviewed (response rate: 71.4%). Of those 2,068 boosted individuals:

0.3% required hospitalization for an adverse event

4.5% experienced one or more neurological problems (2.1% of men and 6.9% of women), such as tingling or itching sensation, Bell’s palsy, vision damage, memory deterioration, hearing damage, convulsions, loss of consciousness and more

9.6% of women under the age of 54 experienced menstrual irregularities. Of those, “39% suffered from similar side-effects after prior COVID-19 vaccinations; however most (67%) indicated that the side-effects waned prior to the third vaccination and returned after receiving it”

26.4% of those with preexisting anxiety disorder or depression experienced a worsening of their symptoms

24.2% of those with preexisting autoimmune disorders experienced exacerbation of disease

Between 6.3% and 9.3% of those with preexisting high blood pressure, lung disease, diabetes and heart disease also reported that their condition was exacerbated after the third booster. A small number of women, but no men, also reported herpes infections (0.4% for herpes simplex infections and 0.3% for herpes zoster). Other key take-home’s from this Israeli report are that:

Side-effects are more common among women and younger people
1 in 10 women suffer menstrual irregularities

Neurological side effects typically don’t appear until about a month after the jab

In the majority of cases, the occurrence of a given side effect was not more severe after the third shot compared to the two previous doses. Put another way, the severity of side effects tends to be the same, regardless of the number of doses, so these finding can perhaps be applied to doses 1 and 2 as well

German Health Insurance Data Show Alarming Side Effect Rates
German health insurance data are also triggering alarms. Andreas Schöfbeck, a board member of a large insurance company called BKK ProVita, shared the data with Die Welt.

They analyzed the medical data of 10.9 million insured individuals, looking for potential COVID jab side effects. To their horror, they found 400,000 doctors’ visits could be realistically attributed to the jab. According to Schöfbeck, extrapolated to the total population of Germany, the total number of doctors’ visits attributable to jab side effects would be 3 million.

“The number that resulted from our analysis are very far away from the publicly announced numbers [by the Ministry of Health]. It would be unethical not to talk about it,” Schöfbeck told Die Welt, adding that the data are “an alarming signal.” As reported by Die Welt (translated from German):

“From January to August 2021 … around 217,000 of just under 11 million BBK policyholders had to be treated for vaccination side effects — while the Paul Ehrlich Institute keeps only 244,576 side effect reports based on 61.4 million vaccinated …

Thus, the number of vaccine side effects would be more than 1,000 percent higher than the PEI reports … With his analysis, Schöfbeck turned to a wide range of institutions — from the German Medical Association and the StiKo to the Paul Ehrlich Institute itself.

He said the figures were a ‘strong alarm signal’ that ‘absolutely must be taken into account in the further use of vaccines.’ His figures could be validated by the same data analyses of other health insurance companies, he says …

Since ‘danger to human life cannot be ruled out,’ he set a deadline of 6 p.m. Tuesday [February 22, 2022] to respond to his letter. As this passed, they turned to the public.”

Getting back to the issue of children and the danger we’re putting them in by giving them this shot, two autopsies of teenage boys who died within days of their COVID jabs revealed the shot caused their deaths. As reported by The Defender:

“The three pathologists, two of whom are medical examiners, published their findings Feb. 14 in an early online release article, ‘Autopsy Histopathologic Cardiac Findings in Two Adolescents Following the Second COVID-19 Vaccine Dose,’ in the Archives of Pathology and Laboratory Medicine.

The authors’ findings were conclusive. Two teenage boys were pronounced dead in their homes three and four days after receiving the second Pfizer-BioNTech COVID-19 dose. There was no evidence of active or previous COVID-19 infection. The teens had negative toxicology screens (i.e., no drugs or poisons were present in their bodies). These boys died from the vaccine.”

Histopathological examination revealed that neither of the boys’ hearts had signs of typical myocarditis. Instead, what they found were changes consistent with catecholamine-mediated stress cardiomyopathy, also known as toxic cardiomyopathy.

This is a temporary kind of heart injury that can develop in response to extreme physical, chemical or emotional stressors. Another common term for this kind of injury is “broken heart syndrome.” Hyperinflammatory states such as severe COVID-19 infection can also cause this kind of injury to the heart.

More details about the medical history of each of the boys and their autopsy findings are reviewed by Pam Popper of Wellness Forum Health in the video above. Curiously, neither of the boys had any symptoms of myocarditis before they died. One had complained of a headache and upset stomach. The other had not mentioned any symptoms. As noted by The Defender:

“This is extremely concerning. These boys had smoldering, catastrophic heart injuries with no symptoms. How many others have insidious cardiac involvement from vaccination that won’t manifest until they get a serious case of COVID-19 or the flu? Or perhaps when they subject themselves to the physical stress of competitive sports?

These findings suggest a significant subset of COVID-19 deaths in the vaccinated could be due to the vaccines themselves. Furthermore, it raises this question: How often does this condition exist in a latent form in vaccinated individuals?”

Myocarditis Risk in Young Men Is Not Rare

U.S. Vaccine Adverse Events Reporting System (VAERS) data also raise questions about the risk of potentially lethal myocarditis, especially in boys. The following slide was presented during a June 23, 2021, meeting convened by the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP), to discuss the risk of myopericarditis.

As you can see, the observed rates of myocarditis and/or pericarditis for several age groups, and especially among males, are significantly higher than the expected background rate.

This is a loud and clear safety signal, yet the ACIP proceeded to recommend the shot to preteens and teens anyway, and in a public statement insisted that myopericarditis is “an extremely rare side effect” that “only an exceedingly small number of people will experience after vaccination.” How can they say that with data like this right in front of their noses?

Based on this VAERS data, the rate of myocarditis is about 6.5 per 100,000 doses in 12- to 17-year-olds. Going back to where we started, 4 million doses are required to prevent a single child, 5 to 11 years of age, from being admitted to the ICU for COVID.

Assuming the rate of myocarditis in 5- to 11-year-olds is identical to that of 12- to 17-year-olds, we could potentially be looking at 260 cases of myocarditis for every ICU admission for COVID that we prevent. On the whole, the COVID jab provides only risk for children under 18, so there’s absolutely no justification for it.

https://www.theepochtimes.com/the-alarming-trends-in-covid-jab-side-effects_4319841.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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How Vaccine Fanatics Fueled Vaccine Skepticism

The development of COVID-19 vaccines is one of the few successes during a pandemic that saw major failures in public health strategy and treatments. While the vaccines can’t prevent transmission, they have reduced mortality. Before the pandemic, there was almost universal trust in vaccines, and vaccine skeptics were a small but vocal minority.

With a life-saving vaccine during a major pandemic, one would expect more vaccine enthusiasm, but instead, it collapsed. What happened?

Ironically, the problem is vaccine fanaticism, which has caused vaccine skepticism, with problematic consequences extending beyond COVID-19 to trust in other vaccines. Vaccine fanaticism comes in many forms.

In their drive to increase uptake, the vaccine fanatics denied basic scientific facts, such as immunity provided by COVID recovery. This, despite numerous careful studies that showed that COVID-recovery provides better protection versus both infection and severe disease than the vaccine. Nevertheless, vaccine fanatics insisted that natural immunity shouldn’t “count” in the vaccine mandate schemes. By denying science, the vaccine fanatics created further public skepticism about the vaccines.

“If they’re lying about natural immunity, maybe they’re lying about vaccine efficacy,” many may have reasoned.

Despite lack of evidence that the COVID-19 vaccines could prevent transmission and mounting evidence in spring and summer 2021 that they couldn’t stop the spread of the disease, Dr. Anthony Fauci and others convinced themselves that COVID-19 could be conquered only if 70 percent, 80 percent, 90 percent, or more of the population was vaccinated. And when the vaccines didn’t live up to scientifically unproven promises, people’s trust in those who over-promised naturally collapsed.

In its pursuit of the impossible goal of COVID suppression by vaccines alone, public health vaccine fanatics induced many people to become skeptical of the COVID-19 vaccine’s benefits.

Public authorities espoused psychological manipulation to induce vaccine uptake. For example, in its April 2021 guidance on mask-wearing, the Centers for Disease Control and Prevention (CDC) gave permission only to the vaccinated to doff the mask. Their reasoning was based on a mistaken belief that vaccinated individuals can’t spread the disease, but also as an inducement to get people vaccinated since mask-wearing is unpleasant.

Encouraged by public health officials, Krispy Kreme offered free donuts to the vaccinated. Some people may have wondered: “If they understood public health, they wouldn’t try to fatten people with donuts. Maybe vaccines are also bad for my health?”

When these tactics failed, the public health establishment embraced vaccine coercion. They instituted vaccine passports to exclude the unvaccinated from participation in civil life, including access to libraries, museums, and restaurants. The federal government went further, using its vast regulatory powers to mandate vaccines as a condition of employment. These coercive actions effectively cast the unvaccinated into second-class citizenship. As they watched the vaccinated and unvaccinated alike contract COVID-19, they undoubtedly began to wonder whether public health truly had their best interests at heart.

Some vaccine fanatics have adopted the repellant tactic of falsely labeling people they disagree with as anti-vaccine. For instance, the British Medical Journal (BMJ) published a tabloid-style slander that epidemiologists and vaccine experts at Oxford, Harvard, and Stanford are opposed to “mass vaccination.” How might readers interpret that statement? “Well, if Harvard, Stanford, and Oxford professors are against the vaccines, maybe I should be too.”

Such false claims fuel vaccine hesitancy by putting the BMJ imprimatur on the lie that medicine and epidemiology professors are anti-vaxxers, when they aren’t. This damages vaccine confidence.

Vaccine fanatics have politicized the vaccine, using it to paint political opponents as science-denying troglodytes by falsely claiming that they’re against vaccines. If a person trusts a particular politician that’s falsely accused of being against vaccines, that person may only hear the false accusation and therefore reject the vaccine. In a public health crisis, such political gameplay has devastating consequences. What should have been a bipartisan achievement of a vaccine being developed and deployed in record time during a pandemic turned into just another tool for a political food fight, fueling vaccine skepticism.

Like all medical interventions, vaccines have some risks, which must be acknowledged in risk-benefit analyses for different population groups. For example, when there were reports of an increased risk of blood clots in young women receiving the J&J vaccine, it made sense to give them a different vaccine while the reports were investigated. Instead, the CDC “paused” J&J vaccinations in all age groups, including older people, for whom it was clear that there was no excess risk and for whom the benefit of the vaccine was the largest. (The CDC fired one of us for opposing that pause in older people.)

Though the CDC later cleared the vaccine, the J&J vaccine uptake never recovered in the United States, with detrimental effects on less affluent, more rural, and other hard-to-reach populations for whom this one-dose vaccine was ideal and life-saving.

In their bid to boost COVID-19 vaccine uptake, the vaccine fanatics have created a widespread movement of vaccine skepticism that didn’t previously exist. The consequences are dire not just for the COVID-19 vaccine but also for vital childhood vaccines. It may be too late for COVID-19, but regaining public trust is crucial to ensure the public’s confidence in other vaccines that are critical to the well-being of children everywhere.

In public health, it isn’t enough to be trusted by only half the population. Since widespread trust is essential, the only solution is for public health to eschew coercion and embrace its traditional principles. Public health should never again manipulate or deny authentic scientific results to manipulate the public’s behavior. It should dismiss practitioners who use public health as a weapon in a cultural or political war. It should reject slander, censoring, and ad hominem attacks.

Trust in vaccines can only be regained through honest, open dialogue, science-based policies, public education, long-term thinking, a strengthened vaccine safety monitoring system, and voluntary vaccinations. That is, it should return to the traditional principles of public health.

https://www.theepochtimes.com/how-vaccine-fanatics-fueled-vaccine-skepticism_4319309.html

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Alarming Warning About COVID Tests

The National Capital Poison Center reports on its website that many quick home COVID-19 antigen tests included a harmful chemical compound that may be dangerous to your children as well as you.

The chemical sodium azide is reportedly a preservative agent in fast antigen sets, consisting of BinaxNow, BD Veritor, Flowflex, as well as Celltrion DiaTrust.

Sodium azide, if ingested, can cause low blood pressure, dizziness, migraine, and heart palpitations.

Now, Ohio, as well as Texas, issued a warning after seeing a rise in records related to sodium azide poisoning, in the very same 500 million Covid test sets that Biden sent to the American public.

An “increase in accidental exposures to a substance in these kits,” was reported by Cincinnati Children’s Hospital Medical Center.

Cincinnati.com reported:

The substance is sodium azide, and Cincinnati Children’s Hospital Medical Center’s Drug and Poison Information Center has seen a surge in calls about exposures to the chemical since more people started self-testing for COVID-19 at home.

“We started getting our first exposures to these test kits around early November,” said Sheila Goertemoeller, pharmacist and clinical toxicologist for the center. “It was, really, all ages.” The calls to the local center mirror what’s been happening nationally.

Sodium azide, often used as a preservative, is a liquid reagent in several of the COVID-19 test kits, she said. Ingesting it can cause low blood pressure, which can result in dizziness, headaches or palpitations. Exposure to it can also cause skin, eye or nostril irritation.

The Cincinnati Children’s based Drug and Poison Information Center has logged 38 cases of sodium azide exposure, with cases peaking in January. Adults exposed generally have experienced mild skin irritation, which can get worse if the area isn’t washed thoroughly, she said.

Nationwide Children’s Central Ohio Poison Center in Columbus also reported seeing an “uptick” in cases, as well, a spokeswoman said. The center did not immediately have a number of cases.

Last week, a cautionary notice was released by the West Texas Poisonous substance Center advising the citizens to read the directions prior to using any kind of at-home COVID-19 testing kits.

Local 12 additionally reported:

Sarah Watkins, medical director, for West Texas Region Poison Center, an Emergency Medicine Physician and medical toxicologist reported an increase of reports related to sodium azide poisoning.

“It has a chemical in it called sodium azide, which in large amounts can be really dangerous and even life-threatening,” Watkins said.

She said the majority of the calls made are from people who are not reading the instructions.

“We have gotten some calls here in the state of Texas about this,” Watkins said.

She said some people are putting the test swab in the solution and sticking it up their nose.

She said people are also confusing the substance for eyedrops.

“In-home covid tests, there is a dropper that comes in the test, and it looks a lot like eyedrops so it’s really easy to confuse with things that you’re supposed to put into your body,” Watkins said.

Watkins said sodium azide reacts on the body the same way cyanide does.

https://patriotunitednews.com/alarming-warning-about-covid-tests-biden-sent-americans/

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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SARS-COV-2 Vaccines and Neurodegenerative Disease

Since December 2020, when several novel unprecedented vaccines against SARS-CoV-2 began to be approved for emergency use, there has been a worldwide effort to get these vaccines into the arms of as many people as possible as fast as possible. These vaccines have been developed “at warp speed,” given the urgency of the situation with the COVID-19 pandemic. Most governments have embraced the notion that these vaccines are the only path towards resolution of this pandemic, which is crippling the economies of many countries.

Thus far, there are four different vaccines that have been approved for emergency use for protection against COVID-19 in the US and/or Europe. Two (the Moderna vaccine and the Pfizer/BioNTech vaccine) are based on mRNA technology, whereas the other two (produced by Johnson & Johnson and AstraZeneca) are based on a double-stranded DNA recombinant viral vector. The mRNA vaccines contain only the code for the SARS-CoV-2 envelope spike protein, whereas the DNA-based vaccines both contain an adenovirus viral vector that has been augmented with DNA that codes for the SARS-CoV-2 spike protein. The DNA-based vaccines have a certain advantage over the RNA-based vaccines in that they do not have to be stored at deep-freeze temperatures, because double-stranded DNA is much more stable than single-stranded RNA. But a disadvantage is that those who have been exposed to natural forms of the adenovirus have antibodies to the virus that will likely block the synthesis of the spike protein, and therefore not afford protection against SARS-CoV-2.

In this regard, the AstraZeneca (AZ) vaccine has a slight advantage over the Johnson & Johnson (J&J) vaccine because the virus normally infects chimpanzees rather than humans, so fewer people are likely to have been exposed to it. On the other hand, several studies have shown that viruses that normally infect one species can cause tumors if they are injected into a different species. For example, a human adenovirus injected into baboons caused retinoblastoma (cancer of the eye) in the baboons . So, it can’t be ruled out that the AZ vaccine could lead to cancer.

People don’t realize that these vaccines are vastly different from the many childhood vaccines we are now used to getting early in life. I find it shocking that the vaccine developers and the government officials across the globe are wrecklessly pushing these vaccines on an unsuspecting population. Together with Dr. Greg Nigh, I recently published a peer-reviewed paper on the technology behind the mRNA vaccines and the many potentially unknown consequences to health . Such unprecedented vaccines normally take twelve years to develop, with only a 2% success rate, but these vaccines were developed and brought to market in less than a year. As a consequence, we have no direct knowledge of any effects that the vaccines might have on our health over the long term. However, knowledge about how these vaccines work, how the immune system works and how neurodegenerative diseases come about can be brought to bear on the problem in order to predict potential devastating future consequences of the vaccines.

The mRNA in these vaccines codes for the spike protein normally synthesized by the SARS-CoV-2 virus. However, both the mRNA and the protein it produces have been changed from the original version in the virus with the intent to increase rate of production of the protein in an infected cell and the durability of both the mRNA and the spike protein it codes for. Additional ingredients like cationic lipids and polyethylene glycol are also toxic with unknown consequences. The vaccines were approved for emergency use based on grossly inadequate studies to evaluate safety and effectiveness.

Our paper showed that there are several mechanisms by which these vaccines could lead to severe disease, including autoimmune disease, neurodegenerative diseases, vascular disorders (hemorrhaging and blood clots) and possibly reproductive issues. There is also the risk that the vaccines will accelerate the emergence of new strains of the virus that are no longer sensitive to the antibodies produced by the vaccines. When people are immune compromised (e.g., taking chemotherapy for cancer), the antibodies they produce may not be able to keep the virus in check because the immune system is too impaired. Just as in the case of antibiotic resistance, new strains evolve within an infected immune-compromised person’s body that produce a version of the spike protein that no longer binds with the acquired antibodies. These new strains quickly come to dominate over the original strain, especially when the general population is heavily vaccinated with a vaccine that is specific to the original strain. This problem is likely going to necessitate the repeated rollout of new versions of the vaccine at periodic intervals that people will have to receive to induce yet another round of antibody production in an endless game of cat and mouse.

Like the mRNA vaccines, the DNA vaccines are based on novel biotech gene editing techniques that are brand new, so they too are a massive experiment unleashed on a huge unsuspecting population, with unknown consequences. Both DNA vector vaccines have been associated with a very rare condition called thrombocytopenia, in which platelet counts drop precipitously, resulting in system-wide blood clots and a high risk of cerebral hemorrhaging [5]. This is likely due to an autoimmune reaction to the platelets, and it comes with a high risk of mortality. In the case of the AZ vaccine, this has caused over 20 European countries to temporarily pause their vaccination programs [6]. And the United States called a temporary halt on the J&J vaccine.......

Summary

There are many reasons to be wary of the COVID-19 vaccines, which have been rushed to market with grossly inadequate evaluation and aggressively promoted to an uninformed public, with the potential for huge, irreversible, negative consequences. One potential consequence is to exhaust the finite supply of progenitor B cells in the bone marrow early in life, causing an inability to mount new antibodies to infectious agents. An even more worrisome possibility is that these vaccines, both the mRNA vaccines and the DNA vector vaccines, may be a pathway to crippling disease sometime in the future. Through the prion-like action of the spike protein, we will likely see an alarming increase in several major neurodegenerative diseases, including Parkinson’s disease, CKD, ALS and Alzheimer’s, and these diseases will show up with increasing prevalence among younger and younger populations, in years to come. Unfortunately, we won’t know whether the vaccines caused this increase, because there will usually be a long time separation between the vaccination event and the disease diagnosis. Very convenient for the vaccine manufacturers, who stand to make huge profits off of our misfortunes — both from the sale of the vaccines themselves and from the large medical cost of treating all these debilitating diseases.

Much more here:

https://www.theepochtimes.com/sars-cov-2-vaccines-and-neurodegenerative-disease_4207235.html

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More inaction needed in dealing with Covid

Despite concerns about the damaging side-effects of restrictions, the public outcry for action in many countries exemplified the urge to act. We acted under the precautionary principle, that the disease was uncharacterised, and it was better to act rather than not, even though we were unsure of the efficacy of such policies. To a certain extent it’s something we are still doing now.

Our hospital and city are experiencing their first real wave of Covid cases, and therefore all staff are required to wear N95 masks, visors, and other PPE. This intervention has gone a long way to immiserating the workforce, many of whom are less than happy at the prospect. Yet despite this, many staff are sick with Covid. This is not a call to stop wearing PPE, but rather a reflection of the fact that there are limitations to our interventions, and regardless of our best intent and fastidious care, people still get sick. This is mirrored around the world where divisions of ‘Covid’ and ‘non-Covid’ areas of facilities have been shown to be arbitrary as infections spread, and, despite the best PPE, staff in these hospitals are still contracting the disease.

Similarly on the issue of vaccination, many of us had hoped this would be a sterilising vaccine, where receiving it reduces an individual’s ability to transmit the virus in a meaningful way. Sadly, this doesn’t appear to be the case. Although the vaccines go a long way to reducing morbidity and mortality in certain populations, they achieve less than we had hoped. With this in mind, the value of denying individuals entry to the public realm on the basis of vaccination status seems less pragmatic, and more moralistic. Similarly for healthcare professionals.

On issues such as border closures, Australia and New Zealand have demonstrated that it is possible to keep a pandemic from the shores for a period of time, but at escalating costs. We must ask ourselves if this is worth the price. Those who are foreign-born feel this most acutely – being unable to see friends and family, including unwell relatives and attending important life events. A great deal of suffering has been caused and now we open our borders millions will catch Covid anyway, and many will die. In defence of the government measures, hopefully many fewer than would have without the vaccines. Ultimately, border closures are not a sustainable policy, and do not allow us to avoid a pandemic.

Of all these interventions, some have more merit than others, indeed, some are more justifiable than others. However, we should be honest about their limitations.

One casualty of the pandemic has been our attitude towards science and the interrogation of ideas. Sadly, it may be that the medical profession has done this to itself. By our compulsion to act, and our hubristic attitude to what we can achieve, we have perhaps been blind to our limitations. Indeed, the fact we have acted to dismiss and belittle people with concerns (some valid, some less so) about our interventions, makes us even less able to impartially appraise our recommendations.

The lack of humility not only fails to reflect our limitations, but undermines the basis upon which we practice. I fear this has only been exacerbated by making certain interventions mandatory, as it will be much harder to admit to ourselves either their limitations or side-effects, if they emerge. This will have damaging consequences to the enquiring scepticism necessary for scientific improvement.

Ultimately, after two years of aggressive interventions, it does not appear that we have a clear panacea. There has been no way to avert mass infections, no way to categorically protect ourselves, and, except for vaccinations, very few interventions with clear-cut efficacy. As health professionals, none of us truly believe that wearing masks and visors will prevent us getting Covid, and experiences from the rest of the world corroborate this.

The Covid virus is here to stay. We do not know how it will affect us in the long-run, but we should perhaps have the humility to appreciate that some of our interventions do not work as well as we would like.

https://spectator.com.au/2022/03/the-danger-of-hubris

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Fauci’s New Actions Revealed After Seemingly Disappearing as COVID Narrative Disintegrates

The left’s favorite COVID scold, Dr. Anthony Fauci, has been conspicuously absent from the national media for the last few weeks, and the outlets he has been relegated to seem to underscore the Democrats’ new strategy on COVID.

Deservedly or not, Fauci has been the face of the Democrat response to the coronavirus, scolding Americans to give away their freedoms for “safety” from the “pandemic,” demanding that we all must be masked — with two masks, even — advocating for our jobs to be shut down and citizens to be locked in their homes and screeching for our schools to be closed. But since early in February, Fauci has gone from appearing on multiple news outlets per day to being nearly invisible to the news-viewing public.

His sudden disappearance, though, seems to coincide with the emerging realization among Democrats that their constant stream of fear porn over the coronavirus is hurting them politically, and their newly inculcated fear that their laser-like focus on draconian COVID mitigation is going to cost them during the 2022 midterm elections.

Radio host Chris Stigall, for instance, recently noted that election consultants are advising the Democrats to “declare victory over COVID and move on,” and quickly usher in a return to normalcy — and conveniently just before the 2022 elections, too.

Democrats are suddenly warning each other in private to drop further COVID restrictions, to open schools and to end mask mandates.

In light of that bubbling undercurrent in Democrat electoral plotting, Anthony Fauci has suddenly been removed from the powerhouse news outlets and has been relegated to lesser-known blogs, publications and the odd Youtube channel.

Indeed, as The Post Millennial noted, Fauci’s news section of the National Institute of Allergy and Infectious Diseases website shows only one appearance in March (by March 5), and a scant 14 appearances in all of February. That is a heavy contrast to previous months. In January, for instance, the NIAID news tracker shows that Fauci made 17 appearances and he clocked a whopping 41 in December!

It certainly appears that the Democrat powers that be have decided that the celebrated doc is now a has-been that they don’t want seen by the American people.

Meanwhile, mask mandates are being dropped even by deep blue states. At the end of February, California, Oregon and Washington state all announced pullbacks on masking to various degrees, according to the Wall Street Journal. And by the beginning of February, even Biden’s homes state of Delaware told citizens that masks were no longer necessary.

The Centers for Disease Control also made an about-face and said that most people can doff the masks and added that masks in schools are not necessary.

The CDC’s new guidelines even prompted a group of researchers to urge schools to dump mask mandates for kids altogether.

The end of masking is also amusing. After all, mask zealots claim without evidence that masks “prevent” people from getting COVID, but now these same people are saying that the numbers are down, so we can throw away our masks. But if masks work, shouldn’t they want to stick with them until the numbers approach zero? Why the sudden decision to dump the masks? “Election Day” seems to be the answer to that question.

With all this just coincidentally occurring in time for the 2022 elections, the timing is suspicious, indeed.

Meanwhile, the vaunted Dr. Fauci’s star is dimming, as he appears on obscure YouTube-style channels in a desperate bid to stay relevant. One would think that appearing with an unknown left-winger on the obscure vlog called “WokeAF” is not the optimal exposure he has become used to.

In case you don’t get that title, “Woke” is clear enough, certainly, but the “AF” stands for “as f*ck.” So, now Fauci has been relegated to appearing on video channels with curse words in their title!

That is quite a fall from grace.

https://flagandcross.com/faucis-new-actions-revealed-after-seemingly-disappearing-as-covid-narrative-disintegrates/

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Time to put the Covid pandemic behind us

Comment from Australia

While we can safely rule out Vladimir Putin as a contender for this year’s Nobel peace prize, he may not yet be out of the running for the Nobel prize in medicine. After all, the invasion of Ukraine has put a stop to Covid-19, or at least the interminable conversations about a waning pandemic.

Omicron may be ripping through Australia and New Zealand somewhat faster than a fleet of Russian tanks but it presents less danger to human life and limb. Putin has presented the world with something far more frightening than a coronavirus mutation: a hostile invasion of a sovereign neighbour that may yet trigger a wider conflict.

The rains saturating the east coast have provided further distraction from the Covid dark opera. And when even The New York Times runs the headline, “Get Out of Your Pyjamas, the Pandemic is Over”, it should be time to call it quits.

International data should give us the confidence to declare that Covid-19 is in its death throes, having accomplished its mission of infecting every community on Earth, even NZ, where daily case numbers per 100,000 people last week were higher than the peaks in either Britain or the US. Thankfully, however, just like everywhere else, almost nobody is dying. The number of active cases across the world has been steadily declining since its Omicron peak in late January. The stockmarket saw it coming. Shares in Moderna and BioNTech are a quarter of the price they were in August and Pfizer has lost around 20 per cent of its value since December.

Last week, the US Senate narrowly passed a resolution to end the state of emergency. Republican senator Ron Marshall from Kansas, who introduced the measure, described it as “a symbolic victory to our citizens that normalcy is around the corner”. Mopping up the executive overreach, however, may be easier said than done.

Few in positions of authority have mustered the courage to declare the pandemic over. The deadly Wuhan virus, which prompted the World Health Organisation to declare a pandemic, is extinct. Omicron is far less deadly. Yet there appears little appetite to review the pandemic status, suggesting there are those who prefer to keep it in place. The people resisting a return to normality are generally in positions of power and influence. They have profited from the pandemic either financially or through a rise in the sense of their importance.

They include many in the mainstream media who, with some honourable exceptions, have kept their fingers on the panic button, even as the risk to public health has declined.

Two weeks ago, former deputy chief health officer Nick Coatsworth told Chris Kenny on Sky News that the Omicron variant was “clearly not” as dangerous to healthy adults and children as influenza. “If you had to give me a choice between which one I would vaccinate (my children) against, every time I would be choosing influenza over a Covid-19 vaccine,” he said. “That’s how I feel about the difference in severity between the two.”

Coatsworth’s advice was based on clinical experience and data. Yet, as Kenny reflected in The Weekend Australian the following Saturday, most of the rest of the media ignored the story. Taking away our liberties came much easier to the elite than handing them back.

Countless rules, regulations and protocols that were put in place when the risk was perceived to be rising remain in place with no prospect of any immediate review. Worse still, many of the measures were put in place without an expiry date, even though the pandemic was bound to pass.

We should have known after 9/11 that rushed measures to deal with a perceived emergency are hard to remove.

The security guards who were put in place to patrol the walkway on the Sydney Harbour Bridge have been strolling pointlessly up and down 24 hours a day for more than 20 years. No one can remember why they were put there, let alone who has the authority to stand them down, but perhaps someone should find out.

Hopefully, the mask “protocol” (not a rule or regulation) in airports and on domestic flights will be scrapped some time before 2040, but you wouldn’t put your money on it. The measure was agreed by national cabinet in January 2021 and updated in October. Transmission of the virus aboard an aircraft is far rarer than most would imagine, thanks to high-back, forward-facing seats and constant fresh air pumped through highly efficient filters. There is no conclusive scientific evidence that a scrappy mask, carelessly worn, is any more capable of stopping the Omicron variant than a hapless security guard could stop a low-flying 737. Yet the rule remains in place, serving as yet another barrier to civilised human interaction and a burden on those required to enforce it.

The absence of open debate is perhaps the most troubling restriction of all. Coatsworth is not the only person to harbour doubts about booster shots for children or whether universal booster shots, not just for the elderly or others at high risk, is a sensible or proportionate policy.

Questioning whether we really need to ostracise the unvaccinated remains a taboo even as state authorities are considering when dismissed workers could be invited back into their jobs to fill the vacancies for skilled staff in health and education.

Last week, the NZ High Court recognised the new reality by upholding an appeal by unvaccinated police and members of the NZ defence force, declaring their dismissal to be unlawful.

The court found their dismissal was not “a reasonable limit on the applicants’ rights that can be demonstrably justified in a free and democratic society”. The expert advice before the court did not show that the dismissal of unvaccinated workers made “a material difference” to health outcomes in the era of Omicron.

In other words, the only justifiable redundancies are the dispensing of superfluous rules.

https://www.theaustralian.com.au/commentary/time-to-put-the-covid-pandemic-behind-us/news-story/cbc6ba92003db828f110358206f8fdc9

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Dodgy science behind British lockdown

Scientists did not have accurate Covid data when they predicted that 500,000 people could die if the UK took no action during the first wave of the pandemic.

Modelling from Professor Neil Ferguson and colleagues at Imperial College London published on March 16, 2020, predicted the NHS would be overwhelmed within weeks and a terrible death toll would arise if nothing was done to stop the spread of the disease.

Prior to the 'Report 9' paper, the Government's initial Covid strategy had been to 'mitigate' the spread and build up 'herd immunity' rather than suppress the first wave.

However, sticking to these plans – allowing the spread to continue but slowing it down with limited measures such as home isolation - would still have resulted in 250,000 deaths, according to Imperial’s mathematical model.

The stark modelling is understood to have single-handedly led to the decision to move away from herd immunity to a national lockdown on March 23.

But minutes from a SPI-M (Scientific Pandemic Influenza Group on Modelling) meeting released to The Telegraph following a Freedom of Information request have shown that, a week earlier, the modellers remained 'uncertain' of case numbers 'due to data limitations'.

Modellers were still waiting for more comprehensive data on mortality from Public Health England and then best estimates on infection fatality rate, hospitalisation rates and the number of patients requiring ICU care were still uncertain.

The team is also understood to have believed that the modelling only showed 'proof of concept' that lockdowns could help deal with Covid, before warning that 'further work would be required'.

Following the release of its model, Imperial College held a press conference, followed by Prime Minister Boris Johnson ordering the public to avoid pubs, restaurants and non-essential social gatherings later the same day.

At the briefing, Prof Ferguson said new conclusions had been drawn as 'the last few days' had provided 'refinements' in estimates of intensive care and hospital demand.

Minutes now show, though, that SPI-M did not believe the data was complete.

The scientific paper published by Professor Ferguson and his colleagues on the Imperial College COVID-19 Response Team was credited for persuading Boris Johnson's Government to ramp up their response to the coronavirus.

The paper, released on March 17, and titled Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand, predicted that the Government's original plan to 'mitigate' the outbreak instead of trying to stop it could have led to a quarter of a million people dying.

Using data from Italy and China, the scientists predicted how different Government measures would have different impacts on the outbreaks.

If no action at all had been taken against the coronavirus it would have claimed 510,000 lives, the team's report said. Had the Government stuck with their strategy of trying to 'mitigate' the spread – allowing it to continue but attempting to slow it down – with limited measures such as home isolation for those with symptoms this number would be roughly halved to 260,000.

If the strictest possible measures are introduced, the number of deaths over a two-year period will fall below 20,000, the scientists said.

Other points in the Imperial College report, titled Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand, included:

Lockdown measures could be brought back if the virus resurfaces after this epidemic is over

The coronavirus outbreak is worse than anything the world has seen since the 1918 Spanish Flu pandemic

Dramatic measures to suppress an outbreak carry 'enormous social and economic costs which may themselves have significant impact on health and well-being'

Virus transmission happens evenly – one third of cases are caught in the home, one third at work or school, and one third elsewhere in the community

People are thought to be infectious from 12 hours before symptoms start, or from four days after catching the infection if someone doesn't get symptoms

Patients who do get symptoms are thought to be 50 per cent more infectious than those who don't

People are thought to develop at least short-term immunity after catching the virus, meaning they can't catch it again

Approximately 4.4 per cent of patients need hospital care. 30 per cent of those need intensive care, and 50 per cent of intensive care patients can be expected to die, according to data from China

The average length of a hospital stay for a coronavirus patient is 10 days – eight days for those who recover quickly; 16 days for those who need intensive care

It comes after critics earlier described the coding used by Imperial as 'totally unreliable'.

John Carmack, an American developer who helped refine the code before the paper was published online two years ago, said some parts of the code looked like they were machine translated from Fortran', an old coding language.

After growing pressure, the Imperial team released their code, which simulates homes, offices, schools and people movement, and sceptics were quick to point out it was 13 years old.

Bob Seely, MP for the Isle of Wight, today described the the modelling as 'a national scandal'

On March 17, minutes show that the Department of Health wanted to ascertain whether Prof Ferguson had referenced other papers in the Imperial model.

The following day, both Imperial and the London School of Hygiene and Tropical Medicine (LSHTM) were asked to renew their models ahead of a Sage meeting scheduled later the same day in which the idea of London-only lockdown would be reviewed due to rising cases.

Data continued to be uncertain throughout the remainder of the year, the minutes show, and on September 23 members said 'operational issues' with NHS Test and Trace had caused further problems and made it 'difficult to interpret trends in the data, and added further uncertainty to the modelling'.

They also show that NHS England was 'unwilling' to share timelines for the vaccine rollout, resulting in difficulty modelling the impact of the jab, while the following week modellers raised concerns over how different data streams were 'presenting conflicting messages' on how Covid was changing.

And models used by the Government for Covid Freedom Day on June 21 last year did not include the most recent figures on vaccine efficacy or Public Health England's weekly vaccine surveillance report.

Prof Ferguson described in December how he had become 'something of a marmite figure' as he admitted he 'made mistakes' and 'oversimplified things' during the pandemic.

The epidemiologist said while it had been challenging for most Western governments to act in a timely manner the science throughout the crisis 'had basically been right'.

However, he admitted he had 'made mistakes for which he apologised for'.

Prof Ferguson resigned from the government's scientific advisory group (SAGE) last year after claims emerged that Antonia Staats visited him at home - in breach of lockdown rules.

Imperial College said its team was 'always open about the uncertainty' of its modelling - especially during the early stages of Covid.

The modellers had been quick to raise concern about outbreaks in care homes and hospitals, while members agreed that 'transmission in healthcare is a significant contributor to cases in hospitals' and required further attention.

And speaking on BBC Radio 4 Today programme, Prof Ferguson said: ''I think the science we have done throughout this pandemic has basically been right, not absolutely every aspect but basically most of it.

'I suppose I didn't anticipate becoming the public figure I suppose I now am, something of a marmite figure if you put it like that.

He added: 'Half a million was if we did nothing at all which was never going to happen but quarter of a million was if we did plan B, if we just tried to flatten the curve.

'There, the point is, to give the population an assessment of the potential level of threat and in some sense the reason for doing that is to explain the need for certain measures.'

https://www.dailymail.co.uk/news/article-10557635/Scientists-did-not-accurate-Covid-stats-prediction-500-000-killed.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Scientists seek to solve mystery of why some people do not catch Covid

Despite quite a bit of exposure, I have had no Covid symptoms, so I may be one of those mentioned below. I do generally have a very good immune system. With a bit of a nudge it even wiped out some stomach cancer. I have had two AstraZenica shots but we know that vaccines are all but useless against Omicron

Phoebe Garrett has attended university lectures without catching Covid; she even hosted a party where everyone subsequently tested positive except her. “I think I’ve knowingly been exposed about four times,” the 22-year-old from High Wycombe said.

In March 2021, she participated in the world’s first Covid-19 challenge trial, which involved dripping live virus into her nose and pegging her nostrils shut for several hours, in a deliberate effort to infect her. Still her body resisted.

“We had multiple rounds of tests, and different methods of testing: throat swabs, nose swabs, other types of swabs that I’d never done before like nasal wicks – where you hold a swab in your nose for a minute – as well as blood tests, but I never developed symptoms, never tested positive,” Garrett said. “My mum has always said that our family never gets flu, and I’ve wondered if there’s maybe something behind that.”

Most people know someone who has stubbornly resisted catching Covid, despite everyone around them falling sick. Precisely how they do this remains a mystery, but scientists are beginning to find some clues.

The hope is that identifying these mechanisms could lead to the development of drugs that not only protect people from catching Covid, but also prevent them from passing it on.

Garrett is not the only challenge trial participant to have avoided becoming infected. Of the 34 who were exposed to the virus, 16 failed to develop an infection (defined as two consecutive positive PCR tests) – although around half of them transiently tested positive for low levels of the virus, often several days after exposure.

Possibly, this was a reflection of the immune system rapidly shutting down an embryonic infection. “In our previous studies with other viruses, we have seen early immune responses in the nose that are associated with resisting infection,” said Prof Christopher Chiu at Imperial College London, who led the study. “Together, these findings imply that there is a struggle between the virus and host, which in our ‘uninfected’ participants results in prevention of infection taking off.”

Some of them also reported some mild symptoms, such as a stuffy nose, sore throat, tiredness, or headache – although, since these commonly occur in everyday life, they may have been unrelated to virus exposure.

“Either way, levels of the virus didn’t climb high enough to trigger detectable levels of antibodies, T cells or inflammatory factors in the blood that are usually associated with symptoms,” Chiu said.

Other studies also suggest it is possible to shake off Covid during the earliest stages of infection, before it establishes a proper foothold. For instance, during the first wave of the pandemic, Dr Leo Swadling at University College London and colleagues intensively monitored a group of healthcare workers who were regularly exposed to infected patients, but who never tested positive or developed antibodies themselves. Blood tests revealed that around 15% of them had T cells reactive against Sars-CoV-2, plus other markers of viral infection.

Possibly, memory T-cells from previous coronavirus infections – ie those responsible for common colds – cross-reacted with the new coronavirus and protected them from Covid.

Understanding how frequently people abort nascent Covid infections in the era of Omicron is complicated because it requires intensive testing – for the virus, antibodies, T cells and other markers of infection – and because so many people have been vaccinated.

“It is likely vaccinated individuals are exposed to the virus, and block viral replication and detectable infection more commonly,” Swadling said.

There is also no commercially available test that can distinguish between immunity triggered by vaccination and the different variants – so unless a person has recently tested positive, it is almost impossible to know if they have been exposed to Omicron or not.

Seasonal coronaviruses may not be the only source of cross-protective immune responses. Prof Cecilia Söderberg-Nauclér, an immunologist at the Karolinska Institute in Stockholm, began investigating this possibility, after Sweden avoided being overwhelmed by cases during the pandemic’s first wave, despite its light-touch approach to restrictions. Mathematical modelling by her colleague, Marcus Carlsson at Lund University, suggested this pattern of infections could only be explained if a large proportion of people had some kind of protective immunity.

Her team scoured databases of protein sequences from existing viruses, hunting for small segments (peptides) resembling those from the new coronavirus, to which antibodies were likely to bind. When they identified a six-amino acid peptide in a protein from H1N1 influenza that matched a crucial part of the coronavirus spike protein, “I almost fell out of my chair,” Söderberg-Nauclér said.

They have since discovered antibodies to this peptide in up to 68% of blood donors from Stockholm. The research, which has not yet been peer-reviewed, could suggest that immune responses triggered by H1N1 influenza – which was responsible for the 2009-10 swine flu pandemic – and possibly related subsequent strains, may equip people with partial, though not complete, protection against Covid-19. “It provides a cushion, but it won’t protect you if an infected person coughs in your face,” Söderberg-Nauclér said.

A small proportion of people may even be genetically resistant to Covid-19. In October, an international consortium of researchers launched a global hunt to find some of them, in the hope of identifying protective genes.

“We are not looking for common gene variants that provide modest protection against infection, what we are looking for is potentially very rare gene variants that completely protect someone against infection,” said Prof András Spaan at the Rockefeller University in New York, who is leading the research.

They are particularly interested in people who shared a home and bed with an infected person, and avoided infection themselves. “For instance, the other day I was talking to an elderly lady from the Netherlands, who took care of her husband during the first wave. The husband was eventually admitted to the ICU, but she spent the week before taking care of him, sharing the same room, and without access to face masks,” said Spaan. “We cannot explain why she did not get infected.”

Such resistance is known to exist for other diseases, including HIV, malaria, and norovirus. In these cases, a genetic defect means some people lack a receptor used by the pathogen to enter cells, so they cannot be infected. “It could well be that, in some individuals, there is such a defect in a receptor used by Sars-CoV-2,” Spaan said.

Identifying such genes could lead to the development of new treatments for Covid-19, in the same way that the identification of CCR5 receptor defects in HIV-resistant people has led to new ways of treating HIV.

Spaan thinks it is unlikely that the majority of those who have avoided Covid are genetically resistant, even if they have some partial immune protection. This means there is no guarantee they will not eventually become infected – as Garrett found out in late January. Having dodged the virus for almost two years, she was shocked when a routine lateral flow test produced an ominous second red line. Shortly afterwards, she developed mild Covid symptoms, but has since recovered.

The irony is that, having avoided catching Covid from close family, friends and in a specialist medical laboratory, it was probably a relative stranger who infected her. “I have no idea where I got it from; it could have been someone in my local choir, or maybe from the gym,” she said.

https://www.theguardian.com/world/2022/mar/02/scientists-seek-to-solve-mystery-of-why-some-people-do-not-catch-covid

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Time to Defund Vaccine and Mask Mandates

President Biden has declared victory over COVID. Congress should take him at his word and defund all of the vaccine and mask mandates now.

Just two weeks ago, Congress received 25 million emails urging them to defund the vaccine mandates in the Continuing Resolution to fund the government. Unfortunately, the Senate failed to do the job by voting 46-47 against a Senator Mike Lee vaccine mandate defund amendment and 44–49 against a separate amendment to defund mask requirements by Senator Ted Cruz.

The vaccine mandate defund amendment lost because four GOP Senators, Lindsey Graham, Mitt Romney, James Inhofe and Richard Burr chose to miss the vote.

Now, with every member of Congress able to be in the Capitol mask free as Democratic pollsters cry to their clients that they need to get beyond COVID for their political survival in November, defunding the enforcement of President Biden’s vaccine mandates in the upcoming Omnibus funding bill must be a Congressional priority.

Even the far left Fairfax County School District, where many federal bureaucrats send their children, have ended their mask requirements. The Washington, D.C. government, a vanguard of wokeness, has ended their draconian vaccine passport policy that prevented the unvaccinated from eating in restaurants or going into hotels, even as they were allowed to work in those same establishments.

But unless Congress defunds the enforcement of the regulations and Executive Orders mandating vaccinations, these onerous restrictions will linger in our health care systems, military, federal civil service and defense contractors like the sword of Damocles hanging over the heads of employees.

The enforcement of many of these edicts remains unresolved in the federal Courts but the threat to people’s livelihoods will remain so long as the regulations and Executive Orders remain on the books unless Congress defangs them through refusing to provide funding for their enforcement.

This should not be controversial. With Democrats desperate to move on from COVID, there should not be a single vote in the House or Senate against Congress asserting their rightful power of the purse by ending funding for the enforcement of these mandates. Not one.

As rare as it might be, this is one time when both those who supported and opposed the mandates should be able to agree that they should be ripped out by the roots rather than being left on the books like dangling live electrical wires waiting to shock unsuspecting passersby who inadvertently brush up against them.

At this time in history, we need every health care worker working. We need every member of our armed services ready to jump into action. We need our federal contractors planning to potentially ramp up production of military equipment and materiel. What we don’t need is for leaders in these areas to worry about the application of arbitrary and out-of-date health rules. We don’t need those who work in these fields looking over their shoulders out of concern for their livelihood due to their religious or health-related choice to not get vaccinated.

https://townhall.com/columnists/rickmanning/2022/03/02/time-to-defund-vaccine-and-mask-mandates-n2603979

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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Pfizer’s COVID-19 Vaccine Goes Into Liver Cells and Is Converted to DNA: Study

Confession: I scoffed when I heard early claims that Covid vaccine alters your DNA. It seems that reality beats the improbable as far as the Pfizer vaccine is concerned. I am glad I had the more conventional AstraZenica shot, not available in the USA due to pressure from America's Big Pharma.

The academic journal article is here. The study was of "in vitro" liver cells but cells elsewhere would presumably be similarly affected. The big question is how extensive such effects are

The messenger RNA (mRNA) from Pfizer’s COVID-19 vaccine is able to enter human liver cells and is converted into DNA, according to Swedish researchers at Lund University.

The researchers found that when the mRNA vaccine enters the human liver cells, it triggers the cell’s DNA, which is inside the nucleus, to increase the production of the LINE-1 gene expression to make mRNA.

The mRNA then leaves the nucleus and enters the cell’s cytoplasm, where it translates into LINE-1 protein. A segment of the protein called the open reading frame-1, or ORF-1, then goes back into the nucleus, where it attaches to the vaccine’s mRNA and reverse transcribes into spike DNA.

Reverse transcription is when DNA is made from RNA, whereas the normal transcription process involves a portion of the DNA serving as a template to make an mRNA molecule inside the nucleus.

“In this study we present evidence that COVID-19 mRNA vaccine BNT162b2 is able to enter the human liver cell line Huh7 in vitro,” the researchers wrote in the study, published in Current Issues of Molecular Biology. “BNT162b2 mRNA is reverse transcribed intracellularly into DNA as fast as 6 [hours] after BNT162b2 exposure.”

BNT162b2 is another name for the Pfizer-BioNTech COVID-19 vaccine that is marketed under the brand name Comirnaty.

The whole process occurred rapidly within six hours. The vaccine’s mRNA converting into DNA and being found inside the cell’s nucleus is something that the Centers for Disease Control and Prevention (CDC) said would not happen.

“The genetic material delivered by mRNA vaccines never enters the nucleus of your cells,” the CDC said on its web page titled “Myths and Facts about COVID-19 Vaccines.”

This is the first time that researchers have shown in vitro or inside a petri dish how an mRNA vaccine is converted into DNA on a human liver cell line, and is what health experts and fact-checkers said for over a year couldn’t occur.

The CDC says that the “COVID-19 vaccines do not change or interact with your DNA in any way,” claiming that all of the ingredients in both mRNA and viral vector COVID-19 vaccines (administered in the United States) are discarded from the body once antibodies are produced. These vaccines deliver genetic material that instructs cells to begin making spike proteins found on the surface of SARS-CoV-2 that causes COVID-19 to produce an immune response.

Pfizer didn’t comment on the findings of the Swedish study and said only that its mRNA vaccine does not alter the human genome.

“Our COVID-19 vaccine does not alter the DNA sequence of a human cell,” a Pfizer spokesperson told The Epoch Times in an email. “It only presents the body with the instructions to build immunity.”

More than 215 million or 64.9 percent of Americans are fully vaccinated as of Feb. 28, with 94 million having received a booster dose.

The Swedish study also found spike proteins expressed on the surface of the liver cells that researchers say may be targeted by the immune system and possibly cause autoimmune hepatitis, as “there [have] been case reports on individuals who developed autoimmune hepatitis after BNT162b2 vaccination.”

The authors of the first reported case of a healthy 35-year-old female who developed autoimmune hepatitis a week after her first dose of the Pfizer COVID-19 vaccine said that there is a possibility that “spike-directed antibodies induced by vaccination may also trigger autoimmune conditions in predisposed individuals” as it has been shown that “severe cases of SARS-CoV-2 infection are characterized by an autoinflammatory dysregulation that contributes to tissue damage,” which the virus’s spike protein appears to be responsible for.

Spike proteins may circulate in the body after an infection or injection with a COVID-19 vaccine. It was assumed that the vaccine’s spike protein would remain mostly at the injection site and last up to several weeks like other proteins produced in the body. But studies are showing that is not the case.

The Japanese regulatory agency’s biodistribution study (pdf) of the Pfizer vaccine showed that some of the mRNAs moved from the injection site and through the bloodstream, and were found in various organs such as the liver, spleen, adrenal glands, and ovaries of rats 48 hours following injection.

In a different study, the spike proteins made in the body after receiving a Pfizer COVID-19 shot have been found on tiny membrane vesicles called exosomes—that mediate cell-to-cell communication by transferring genetic materials to other cells—for at least four months after the second vaccine dose.

The persistence of the spike protein in the body “raises the prospect of sustained inflammation within and damage to organs which express the spike protein,” according to experts at Doctors for COVID Ethics, an organization consisting of physicians and scientists “seeking to uphold medical ethics, patient safety, and human rights in response to COVID-19.”

“As long as the spike protein can be detected on cell-derived membrane vesicles, the immune system will be attacking the cells that release these vesicles,” they said.

Dr. Peter McCullough, an internist, cardiologist, and epidemiologist, wrote on Twitter that the Swedish study’s findings have “enormous implications of permanent chromosomal change and long-term constitutive spike synthesis driving the pathogenesis of a whole new genre of chronic disease.”

Whether the findings of the study will occur in living organisms or if the DNA converted from the vaccine’s mRNA will integrate with the cell’s genome is unknown. The authors said more investigations are needed, including in whole living organisms such as animals, to better understand the potential effects of the mRNA vaccine.

“At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Further studies are needed to demonstrate the effect of BNT162b2 on genomic integrity, including whole genome sequencing of cells exposed to BNT162b2, as well as tissues from human subjects who received BNT162b2 vaccination,” the authors said.

https://www.theepochtimes.com/pfizers-covid-19-vaccine-goes-into-liver-cells-and-is-converted-to-dna-study_4307594.html?slsuccess=1

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Explaining vaccine rejection

The 2020–2022 pandemic split parties and ideologues, separated friend from friend and family members from family members. Neighbors were dangerous, and strangers even more so: the invisible enemy stalking our lands overturned every other concern in life: The conflicts it spurred replaced bonds of affection with fear and hatred.

More than ever, we need calm and level-headed thinkers, honest and willing to admit past errors, with eyes wide open for the corruption of industry or government itself. In other words, we need as little politics as humanly possible. As I wrote in a previous piece: we need “people without a clear ideological position, and who can thus appeal to audiences across the political spectrum.”

Two sane figures recently attempted the impossible: to speak calmly to the other side, trying earnestly to explain what happened—Konstantin Kisin, of the popular show Triggernometry, and Columbia sociology professor Musa al-Gharbi.

Kisin begins his monologue with “You’re struggling to understand why some people are vaccine hesitant. Let me help you.”

He uses no study result, no appeal to the biological effect of the drug that has become the main symbol of the Covid conflict; no death rates or R0; no projection of spread or what number of lives lockdowns may or may not have saved. Instead Kisin, for 13 spellbinding minutes, walks us through the many good reasons that people had—before and during Covid—to distrust the elites in politics, business, and media. If this is a question of (dis)trusting the establishment (including “the” Science), you must ask what the establishment did to no longer deserve that trust.

The tale begins years ago, with the Brexit vote and with the election of Donald Trump. Those events shocked the pompous leaders of the universities, the pollsters who confidently said it wouldn’t happen, the media pundits who so convincingly described to us the madness of such prospects.

For a brief moment after the unthinkable had happened, if you recall, there was an earnest desire for inclusivity—for inviting in the views that had gone overlooked in the other half of these countries. Outlets like the New York Times made an effort to portray conservative views and show the kinds of people who had long felt alienated and ostracized from civilized society. As despicable and difficult it was for their core audience to see, revealing perspectives and objections is better than silencing and hiding them.

The efforts didn’t last long and in 2019 and 2020, the monolithic thoughts that dominate these institutions willingly put their blinders on—tighter and more aggressively than before.

Kisin’s final minute is the most powerful thing in these disease-ridden past two years:

“The same people who told you Brexit would never happen; Trump would never win, and that when he did win, it was because of Russian collusion, then because of racism; that you must follow lockdown rules while they don’t; that masks don’t work and then that they do; that protests during lockdowns are a health intervention; that ransacking black communities in the name of fighting racism is mostly peaceful justice; that Jussie Smollett was the victim of a hate crime; that men are toxic; that there’s an infinite number of genders; that Covid didn’t come from a lab, and then that it probably did; that closing borders is racist, and then that it’s the most important thing to do; that the Hunter Biden story is Russian disinformation, and then that it’s not; that they would not take Trump’s vaccine, and then that you must take the vaccine; that Governor Cuomo is a great Covid leader, and then that he’s a granny killer and a sex pest; that the number of Covid deaths is one thing and then another; that hospitals are filled with Covid patients, and then that many of them caught Covid in hospital.

These are the same people now telling you that the vaccines are safe, you must take it, and if you don’t you will be a second-class citizen.

Understand vaccine hesitancy now?”

https://www.theepochtimes.com/skepticism-as-a-new-way-of-life_4302371.html

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Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com/ (TONGUE-TIED)

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