Thursday, June 02, 2022

CDC Director Issues Alert on Pfizer’s COVID-19 Pill: ‘You Might Get Symptoms Again’

Centers for Disease Control and Prevention Director Rochelle Walensky warned that Pfizer’s COVID-19 pill Paxlovid can lead to a rebound in symptoms.

“If you take Paxlovid, you might get symptoms again,” Walensky told CBS News on Tuesday. “We haven’t yet seen anybody who has returned with symptoms needing to go to the hospital. So, generally, a milder course.”

Another researcher who is not affiliated with the CDC said that he has observed such a scenario.

“People who experience rebound are at risk of transmitting to other people, even though they’re outside what people accept as the usual window for being able to transmit,” Dr. Michael Charness of the Veterans Administration Medical Center in Boston told CNN on Tuesday.

After a patient recovers from COVID-19, the aforementioned rebound has occurred between two and eight days later, according to the CDC. The agency, however, told CBS that the benefits of taking Paxlovid outweigh the risks of COVID-19, namely among those who are at a high risk of developing severe symptoms from the virus.

About a week ago, the agency issued an alert to health care providers about the rebound, saying that patients who took Paxlovid either test positive for the virus after having tested negative or will experience COVID-19 symptoms.

“A brief return of symptoms may be part of the natural history of SARS-CoV-2 infection in some persons, independent of treatment with Paxlovid and regardless of vaccination status,” the federal health agency said at the time. SARS-CoV-2 is another name for the CCP (Chinese Communist Party) virus, which causes COVID-19.

“Limited information currently available from case reports suggests that persons treated with Paxlovid who experience COVID-19 rebound have had mild illness; there are no reports of severe disease. There is currently no evidence that additional treatment is needed with Paxlovid or other anti-SARS-CoV-2 therapies in cases where COVID-19 rebound is suspected,” the CDC added.

The Epoch Times has contacted Pfizer for comment. Pfizer told CBS that it is observing a rebound rate of approximately 2 percent and is continuing to monitor patients.

“We have not seen any [COVID-19] resistance emerge to date in patients treated with Paxlovid,” a spokesperson for the company told Reuters this week.

In recent weeks, doctors have increasingly prescribed Paxlovid, which has been authorized to treat at-risk people. But some health care workers told Reuters they are putting off prescribing the medication.

“I am shying away from giving it to people who are very low- risk, and are not terribly ill, particularly people who are vaccinated and boosted,” said Dr. Bruce Farber, chief of public health and epidemiology for Northwell Health, in an interview with the news agency. He will still prescribe the bill to people who have significant health conditions or are aged 75 and older.


WHO European director Dr Hans Kluge says monkeypox requires 'urgent' action

People should reduce their number of sexual partners to help fight the spread of monkeypox, the World Health Organization has urged.

Dr Hans Kluge, the head of WHO's European division, has warned the current outbreak of the tropical disease 'may not be containable'.

He warned Europe had become the new epicentre of the virus, with the outbreak linked to sexual transmission at raves and festivals on the continent.

Dr Kluge insisted the virus 'will not require the same extensive population measures' as Covid but said 'significant and urgent' action was needed to prevent more cases.

The WHO stopped short of calling for contacts of known cases to be quarantined but called for 'critical' twice-daily temperature checks and 'close monitoring'.

Dr Kluge said that while cases have been concentrated in men who have sex with men, there was nothing stopping it from spreading to other groups.

The WHO earlier this week upgraded the global threat level to 'moderate', warning that community spread could lead to vulnerable patients or children catching the virus, which also spreads from touch, or interaction with contaminated surfaces or clothes.

In total, there have been 606 confirmed cases of monkepox across the globe, with 130 more suspected since the first infection was found at the start of May.

Around 70 per cent of the confirmed or suspected cases have been in Europe, with the UK count now at 190. Only Spain has seen more cases.

The LGB Alliance — a trans-exclusionary gay rights group — attracted criticism on Monday after calling for all commercial sex venues to be closed ahead of Pride month, which begins today.

UK monkeypox cases rise to 190 as 11 more Brits test positive
Another 11 monkeypox cases were recorded in Britain yesterday, health officials announced.

The UK Health Security Agency (UKHSA) said the new patients were all in England, bringing the UK total to 190.

Officials said the 'risk to the general public from monkeypox is still low' but it is advising anyone with a new rash or scabs to self-isolate.

Until now, those with suspected or confirmed cases of the tropical disease were being urged to seek advice from NHS 111 or a sexual health service.

But officials said the move to introduce quarantine was to prevent further spread 'now that community transmission is occurring here in the UK and other countries'.

Experts have previously linked the outbreak to two festivals in Europe: The Gran Canarian pride festival, held between May 5 and 15, and a large-scale fetish festival in Antwerp, which ran from May 5 to May 8.

The UK Health Security Agency (UKSA) updated its own guidance on Monday night to tell people to wear condoms during sex for eight weeks after clearing the virus.

Anyone in Britain who develops a new rash or blister is being urged to quarantine and call 111 — and not to leave isolation 'until you've been told what to do'.

They are also been ordered to abstain from sex or close contact with others 'until their lesions have healed and the scabs have dried off'.

Dr Kluge said in a statement last night: '[Europe] remains at the epicentre of the largest and most geographically widespread monkeypox outbreak ever reported outside of endemic areas in western and central Africa.

'Based on the case reports to date, this outbreak is currently being transmitted through social networks connected largely through sexual activity, primarily involving men who have sex with men.

'Many — but not all cases — report fleeting and/or multiple sexual partners, sometimes associated with large events or parties.'

Dr Kluge said all young people, regardless of gender or sexuality, are at risk of the virus and should be aware of the symptoms.

He said gay and bisexual communities have shown 'rapid health-seeking behaviour', adding 'we should applaud them' for coming forward with symptoms early.

But he warned festivals and parties planned over the coming months could lead to further outbreaks of the virus.

He said: 'The potential for further transmission in Europe and elsewhere over the summer is high.

'Monkeypox has already spread against the backdrop of several mass gatherings in [Europe].

'Over the coming months, many of the dozens of festivals and large parties planned provide further contexts where amplification may occur.'

The WHO said event organisers should share 'accurate, practical and targeted information' with attendees over summer.

The LGB Alliance had a statement calling for gay saunas to be closed taken down by Twitter on Monday.

In the statement, the group said: 'Monkeypox is spreading and gay and bisexual men have been affected disproportionately.

'That’s why we are calling on all commercial sex venues, such as saunas, leather/fetish bars and clubs with dark rooms to be closed for a month.'

Critics accused the group of homophobia, arguing the move would lead to stigmatisation ahead of Pride month.

But LGBA insisted the move would have helped 'save Pride' by preventing huge outbreaks just before the main events scheduled over the next four weeks.

Malcolm Clark, head of research at LGBA, told the Daily Telegraph: 'We were really lucky this time that it wasn't another Aids, but what would have happened if it was?

'We would have been complaining about stigmatisation and still taking our time. It appears that 30 years after HIV, we haven't learnt anything.

'It's pure luck that this is a disease nobody dies from, but it could have easily been something else, it could have easily been worse. We should thank our lucky stars.'

Andy Seale, from the WHO's department for HIV, hepatitis and sexually transmitted infections, on Monday said Pride parades pose little risk of spreading monkeypox.

He said most transmission is linked to 'enclosed spaces' such as nightclubs and there is no 'enhanced risk' of transmission at the annual celebrations.




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