Thursday, February 15, 2024




Hospitalized COVID-19 Patients at Higher Odds for Long COVID—Large 3+ Million Patient CDC-Backed Study

This is not exactly surprising. If they were hospitalized,they were sicker to start with

A group of medical researchers targeting real-world data via electronic health records (EHR) known as PCORnet Network Partners sought to better understand post-acute sequelae of SARS-CoV-2 (PASC), another term for long COVID by comparing the occurrence of specific COVID-associated symptoms against conditions as potential PASC 31-to 150-day following a SARS-CoV-2 test among both adults and children with positive and negative test results. The group conducted this retrospective cohort study by tapping into the EHR data from 43 PCORnet sites participating in a national COVID-19 surveillance program.

This study included 3,091,580 adults (316,249 SARS-CoV-2 positive; 2,775,331 negative) and 675,643 children (62,131 positive; 613,512 negative) who had a SARS-CoV-2 laboratory test during March 1, 2020–May 31, 2021, documented in their EHR. The investigators employed use of logistic regression to calculate the odds of having a symptom and Cox models to calculate the risk of having a newly diagnosed condition associated with a SARS-CoV-2 positive test. Represented by Harvard Medical School physician-epidemiologist Jason Block, MD, MPH, the authors report, “Patients with SARS-CoV-2 infection, especially those who were hospitalized, were at higher risk of being diagnosed with certain symptoms and conditions after acute infection.”

With the outcomes published in BMC Infectious Diseases, the entire study was part of PCORnet, the national research network of health systems set up to facilitate multi-site research using EHR data via a standardized common data model across all sites. The 43 PCORnet sites participating in the national COVID-19 surveillance program were funded by the Centers for Disease Control and Prevention (CDC).

Findings

Once adjusting baseline covariates, Dr. Block and colleagues report, “Hospitalized adults and children with a positive test had increased odds of being diagnosed with ≥ 1 symptom (adults: adjusted odds ratio[aOR], 1.17[95% CI, 1.11–1.23]; children: aOR, 1.18[95% CI, 1.08–1.28]) or shortness of breath (adults: aOR, 1.50[95% CI, 1.38–1.63]; children: aOR, 1.40[95% CI, 1.15–1.70]) 31–150 days following a SARS-CoV-2 test compared with hospitalized individuals with a negative test.”

Those patients who were both hospitalized and tested positive for COVID-19 faced greater odds of diagnoses with ≥ 3 symptoms or fatigue compared with those patients testing negative.

“The risks of being newly diagnosed with type 1 or type 2 diabetes (adjusted hazard ratio[aHR], 1.25[95% CI, 1.17–1.33]), hematologic disorders (aHR, 1.19[95% CI, 1.11–1.28]), or respiratory disease (aHR, 1.44[95% CI, 1.30–1.60]) were higher among hospitalized adults with a positive test compared with those with a negative test.”

According to the PCORnet Network Partners analyses, adult patients non-hospitalized but with a positive COVID-19 test face higher odds, or increased risk, of being diagnosed with certain symptoms or conditions.

Limitations

An observational study this study isn’t designed to conclusively prove causation. The authors identify several limitations included in the published output. For example, there are inherent limitations based on the specific set of medical records used for this study. All sorts of complex assumptions must be made to overcome various biases and the like. The findings must be interpreted cautiously.

********************************************

Ventricular Tachycardia Cardiac Arrest after mRNA COVID-19 Vaccination

Researchers Fail to Assess Myocardial mRNA/Spike Protein and Loading Death Reports with Incongruous "Mild" and "Benefits Outweigh Risk" Statements

By Peter A. McCullough, MD, MPH

As the modern world is recognizing record numbers of unexpected deaths with no antecedent disease as a result of cardiac arrest, the medical literature is begrudgingly allowing sporadic case reports to be published. It is reasonable to conclude there must be tremendous resistance against publishing large series of cardiac arrests. The bias probably starts with the doctors who are receiving these cases in the emergency room with CPR in progress.

Minato et al, reported a fatal vaccine-induced ventricular tachycardia arrest in a man around age 40 years the day after Pfizer-BioNTech COVID-19 mRNA vaccination. As a cardiologist, I see this case as a straightforward myocarditis cardiac arrest. However the manuscript is laced with statements that seem to placate fellow authors, reviewers and editors on continued mass vaccination. For example, without presenting any data, the authors state “in most cases the symptoms are mild and tend to resolve on their own.” Later in the abstract “the benefits of vaccination appear to outweigh the benefits.”

These statements are juxtaposed to their description of a completely unnecessary death of a Japanese man in his forties. The authors fail to stain for mRNA or Spike protein or in heart tissue. When evaluated, both have been found in fatal cases such as this making it abundantly clear it was a vaccine death (Krauson et al, Baumeier et al).

This paper serves the purpose of 1) reporting a exemplary case of fatal COVID-19 vaccine myocarditis, 2) to show the biased psychology of researchers, reviewers, and editors who are still in mass formation and pursuing continued vaccination no matter how many more cardiac arrests occur among the vaccinated.

*************************************************

Also see my other blogs. Main ones below:

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com (AUSTRALIAN POLITICS)

http://snorphty.blogspot.com (TONGUE-TIED)

https://immigwatch.blogspot.com (IMMIGRATION WATCH)

https://awesternheart.blogspot.com (THE PSYCHOLOGIST)

http://jonjayray.com/blogall.html More blogs

*********************************************************

No comments: