Tuesday, March 30, 2021

Good news: Pfizer and Moderna's vaccines are 90% effective at preventing COVID-19 infection after two doses and 80% effective after one shot, real-world study of health care workers finds

Two doses of either Moderna's or Pfizer-BioNTech's coronavirus vaccine are highly effective at preventing infection, a new Centers for Disease Control and Prevention (CDC) real-world study published on Monday finds.

Researchers looked at vaccination rates among nearly 4,000 healthcare employees, first responders, and other essential and frontline workers from mid-December 2020 to mid-March 2021.

Results showed the risk of infection among fully vaccinated workers was reduced by 90 percent two or more weeks after the final dose - the amount of time it takes to produce antibodies.

What's more, the risk decreased by 80 percent among people who had only received their initial dose of the vaccine.

'This study shows that our national vaccination efforts are working. The authorized mRNA COVID-19 vaccines provided early, substantial real-world protection against infection for our nation's health care personnel, first responders, and other frontline essential workers,' said CDC Director Dr Rochelle Walensky in a statement.

'These findings should offer hope to the millions of Americans receiving COVID-19 vaccines each day and to those who will have the opportunity to roll up their sleeves and get vaccinated in the weeks ahead. The authorized vaccines are the key tool that will help bring an end to this devastating pandemic.'

It comes as Moderna announced on Monday that it has shipped its 100 millionth dose, out of a 300-million-dose order, to the U.S. government.

At the same time, 10 states plan to open eligibility of vaccines to all adults this week, in line with President Joe Biden's goal of making every adult eligible for a shot by May 1.

So far, just Arkansas and Wyoming -have not yet confirmed plans to expand eligibility ahead of or by the deadline, likely due to clinicians still prioritizing high-risk groups and differences that vary state-by-state in supply and demand of the shots.

For the CDC's study, researchers looked at the vaccination status of 3,950 frontline workers in six states from December 14, 2020 to March 13, 2021.

During that time period, 62.8 percent of workers, or 2,479, received both doses of either the Moderna or Pfizer vaccine, and 12.1 percent, 477 workers, received one dose.

The remaining 25.1 percent of frontline or essential employees were unvaccinated.

Participants were surveyed for symptoms of COVID-19 including cough, fever, chills, shortness of breath and loss of taste or smell through weekly text messages, email or in-person appointments.

The workers received nasal swabs each week, regardless of whether or not they had symptoms, and had an additional swab collected if they reported feeling ill.

Over the course of the study, 172 COVID-19 infections were identified. Of those, 161 were among workers who had not been vaccinated yet.

By comparison, just eight of the partially immunized participants were infected as were three of the fully immunized participants.

This means fully vaccinated workers were 53.6 times less likely to test positive for COVID-19 than those who were not vaccinated.

Even one dose offered substantial protection with partially immunized workers 26.8 times less likely to contract the disease that unvaccinated workers.

According to the CDC, this shows that under real-world conditions, Moderna's and Pfizer's vaccines are 80 percent effective after one dose and 90 percent effective after two doses.

'The findings complement and expand upon these preceding reports by demonstrating that the vaccines can also reduce the risk for infection regardless of COVID-19–associated illness symptom status,' the authors wrote.

'Reducing the risk for transmissible infection..is especially important among health care personnel, first responders, and other essential and frontline workers given their potential to transmit the virus through frequent close contact with patients and the public.'

On Monday, Moderna announced it had shipped 100 million doses of its COVID-19 vaccine to the U.S. government.

The company says it expects to meet its agreement with the administration and deliver its second batch of 100 million doses by the end of May and the third batch of 100 million by the end of July.

'I would like to thank the millions of people who have put their confidence in Moderna's science and our COVID-19 vaccine,' said Moderna CEO St├ęphane Bancel in a statement.

'We are encouraged by the fact that more than 67 million doses have been administered in the U.S. and we are humbled to know that we are helping address this worldwide pandemic with our vaccine.

Moderna said its vaccine shipments has risen five-fold - from more than 16 million doses in the fourth quarter of 2020 to 88 million doses in the first quarter of 2021 - since its inoculation received emergency authorization from the U.S. Food and Drug Administration in December.

This week, the U.S. government ramped up its shipments of COVID-19 vaccines, about 27 million per week, after about a month of sluggish weekly deliveries, so states can finish vaccinating high-risk groups and make the shots available to all.


The Lockdowns Were One Big Fat Mistake

Like nearly all U.S. states, Georgia imposed a stay-at-home order in March 2020 in response to demands from public health officials claiming a stay-at-home order would lessen total deaths from COVID-19.

But unlike most states, Georgia ended its stay-at-home order after only five weeks, and proceeded to lower other restrictions quickly.

The legacy media responded with furious opposition. For example, an article in The Atlantic declared the end of Georgia’s lockdown to be an “experiment in human sacrifice.” The Guardian approvingly quoted one Georgian who insisted the end of the stay-at-home order was “reckless, premature and dangerous.”

A few weeks later, other states began to end their stay-at-home orders and to end other restrictions as well. Florida was the largest among these states.

Shortly thereafter the Daily Beast declared that the scaling back of restrictions in Georgia and Florida was “terrifyingly premature,” and quoted one expert who insisted, “If you lift the restriction too soon, a second wave will come, and the damage will be substantial both medically and economically. We don’t want to throw away the sacrifices we have made for weeks now.”

All this hyperbole about human sacrifice and recklessness leads us to conclude that states which ended lockdowns quickly must have experienced far worse numbers of deaths from covid than states which maintained lockdowns longer. Indeed, when it came to lockdowns, we were told, the longer the better. Ideally, lockdowns shouldn’t be loosened up at all until everyone can be vaccinated.

But things didn’t turn out that way. Experts have scrambled to come up with explanations for why this is the case, but the fact remains some of the most strict states (i.e., New York and Massachusetts) have covid deaths at far worse rates than the “reckless” states like Georgia and Florida.

Moreover, with little to show for their lockdowns in terms of “public health,” these states with extreme lockdowns also have some of the worst unemployment rates. This occurred in spite of the fact that experts insisted that a failure to impose lockdowns would doom a state’s economy to later economic disaster.

State-to-State Comparisons Aren’t Helping the Prolockdown Narrative

A year after stay-at-home orders began, even the usual media outlets are being forced to recognize the outcomes aren’t what was predicted. The Associated Press reported earlier this week:

California and Florida both have a COVID-19 case rate of around 8,900 per 100,000 residents since the pandemic began, according to the federal Centers for Disease Control and Prevention. And both rank in the middle among states for COVID-19 death rates—Florida was 27th as of Friday; California was 28th.

Connecticut and South Dakota are another example. Both rank among the 10 worst states for COVID-19 death rates. Yet Connecticut Gov. Ned Lamont, a Democrat, imposed numerous statewide restrictions over the past year after an early surge in deaths, while South Dakota Gov. Kristi Noem, a Republican, issued no mandates as virus deaths soared in the fall….

Like Florida, Missouri had no statewide mask mandate, ended business restrictions last June and has a cumulative COVID-19 death rate similar to California’s.

Even the LA Times was forced to admit this reality, although they insisted that when you consider the higher levels of poverty and “overcrowding” in California—translation: California is a filthy breeding ground for disease—California should have had far worse rates than Florida for covid deaths. Thus, the LA Times concludes, “California better controlled the virus.”

The LA Times goes on to point to the fact Florida’s covid death rate, while similar, is nonetheless 6 percent higher than California’s, and this translates to three thousand deaths that presumably wouldn’t have happened if Florida had adopted lockdown rules similar to California.

But the numbers don’t stack up so well in favor of lockdowns if we use the LA Times‘s method to make other comparisons. For example, New York’s total deaths-per-million rate is 67 percent higher than Florida’s. Translated into raw numbers, that means if Florida were like New York, Florida would have experienced 54,000 deaths instead of the 33,000 that the CDC now attributes to covid in Florida. (New Jersey’s outcomes are even worse than New York’s.)

Similarly, if Florida were like Massachusetts in its outcomes, Florida would have experienced 54 percent more deaths.

If the LA Times is going to claim overcrowding should translate into more death in California, it should also note that Florida fares worse than California in terms of median age and incidence of obesity. Since advanced age and obesity are major factors in covid hospitalizations and deaths, we might conclude it is Florida, and not California, that is primed for especially bad covid numbers.

(According to the CDC, Florida and New York are evenly matched in terms of obesity, Florida has more obesity than Massachusetts, and Florida has the highest median age of them all.)

And what about Georgia, that experiment in human sacrifice? Well, the CDC reports Georgia’s total deaths-per-million rate at 1,720. That’s worse than California’s rate of 1,400, but Georgia is still far and away better than New York, New Jersey, and Massachusetts, which have rates of 2,530, 2,690, and 2,400, respectively.

What about Economic Performance?

Meanwhile, it is likely that the economies of Florida and Georgia have suffered less. Although the Daily Beast assured us that the “damage will be substantial both medically and economically” if a state ends lockdowns “too soon,” we now find that the unemployment rates in Florida and Georgia are 4.8 and 5.1, respectively.

In California, the picture is quite different, where the unemployment rate now sits at 9 percent. New York doesn’t fare much better, with an unemployment rate of 8.8 percent. New Jersey clocks in at 7.9 percent.

In other words, the dire predictions surrounding states that first canceled stay-at-home orders have been spectacularly wrong. Many lockdown enthusiasts will now do what the LA Times did: quibble over small differences between Florida and California to show that California did a little bit better. New York, of course, will just be completely ignored.

As one doctor at UC San Francisco admitted: “One might’ve expected that the Floridas of the world would’ve done tremendously worse than the Californias of the world… ” Places like Florida and Georgia were supposed to be overwhelmed by an absolute tsunami of death if they were “reckless” in ending COVID restrictions. That didn’t happen.


Also see my other blogs. Main ones below:

http://snorphty.blogspot.com (TONGUE-TIED)

http://edwatch.blogspot.com (EDUCATION WATCH)

http://antigreen.blogspot.com (GREENIE WATCH)

http://pcwatch.blogspot.com (POLITICAL CORRECTNESS WATCH)

http://australian-politics.blogspot.com/ (AUSTRALIAN POLITICS -- Daily)

http://awesternheart.blogspot.com.au/ (THE PSYCHOLOGIST)

https://heofen.blogspot.com/ (MY OTHER BLOGS)


No comments: